Survey on retinopathy of prematurity (ROP) in Italy

This study aims to investigate the incidence and the relative risk factors of retinopathy of prematurity (ROP) and posterior-ROP (P-ROP): ROP in Zone I and posterior Zone II, as well as to analyze the occurrence of surgical treatment of ROP and to evaluate the short term outcome of the disease in Italy

Eddy transport as a key component of the Antarctic overturning circulation

The exchange of water masses across the Antarctic continental shelf break regulates the export of dense shelf waters to depth as well as the transport of warm, mid-depth waters towards ice shelves and glacial grounding lines. The penetration of the warmer mid-depth waters past the shelf break has been implicated in the pronounced loss of ice shelf mass over much of west Antarctica. In high-resolution, regional circulation models, the Antarctic shelf break hosts an energetic mesoscale eddy field, but observations that capture this mesoscale variability have been limited. Here we show, using hydrographic data collected from ocean gliders, that eddy-induced transport is a primary contributor to mass and property fluxes across the slope. Measurements along ten cross-shelf hydrographic sections show a complex velocity structure and a stratification consistent with an onshore eddy mass flux. We show that the eddy transport and the surface wind-driven transport make comparable contributions to the total overturning circulation. Eddy-induced transport is concentrated in the warm, intermediate layers away from frictional boundaries. We conclude that understanding mesoscale dynamics will be critical for constraining circumpolar heat fluxes and future rates of retreat of Antarctic ice shelves

Gratitude as a Variable of Mediation between Parental Support and Self-Esteem in Adolescence

Despite there has been a growing interest in the study of gratitude, few studies have investigated which factors support and promote it; notably, no study has yet addressed ways in which parents could promote gratitude in their children. The present study aims to investigate the relation between parental emotional support and self-esteem through the mediation of gratitude. The analyses have been conducted considering both the maternal and the paternal roles. To that end, an explorative model has been proposed of these relations. A self-report questionnaire was administered to 279 15–19 year-old adolescents (M = 16.83, SD = .85) living in Northern Italy. Findings show that (a) the mother’s emotional support, but not the father’s, sustains gratitude, and (b) gratitude completely mediates the relation between maternal emotional support and self-esteem. Limitations and research implications are discussed

Is prolonged low-dose glucocorticoid treatment beneficial in community-acquired pneumonia?

Community-acquired pneumonia (CAP) has a significant impact on public health in terms of short-term and long-term morbidity and mortality. Irrespective of microbiological etiology, the host's inability to fully downregulate systemic inflammation is the dominant pathogenetic process contributing to acute and long-term morbidity and mortality in CAP. Glucocorticoids are the natural regulators of inflammation, and their production increases during infection. There is consistent evidence that downregulation of systemic inflammation with prolonged low-dose glucocorticoid treatment in patients with severe sepsis and acute respiratory distress syndrome improves cardiovascular and pulmonary organ physiology. A recent meta-analysis of pooled controlled small trials (n = 970) of patients admitted with CAP found improved short-term mortality in the subgroup with severe CAP and/or receiving >5 days of glucocorticoid treatment. We have expanded on this meta-analysis by including patients with CAP recruited in trials investigating prolonged low-dose glucocorticoid treatment in septic shock and/or early acute respiratory distress syndrome (n = 1,206). Our findings confirm a survival advantage for severe CAP (RR 0.66, 95% confidence interval 0.51-0.84; p = .001). A large randomized trial is in progress to confirm the aggregate findings of these small trials and to evaluate the long-term effect of this low-cost treatment