14 research outputs found
Phase II protocol for the evaluation of new treatments in patients with advanced gastric carcinoma: results of ECOG 5282
Non-response in a survey of cardiovascular risk factors in the Dutch population: Determinants and resulting biases
Minimally invasive treatment for anterior pelvic ring injuries with modified pedicle screw-rod fixation: a retrospective study
Systemic Mastocytosis: Retrospective Review of a Decade's Clinical Experience at the Brigham and Women's Hospital
Personalizing and targeting therapy for COPD - The role of molecular and clinical biomarkers
Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease characterized by persistent airflow limitation. It is the third leading cause of death worldwide, and there are currently no curative strategies for this disease. Many factors contribute to COPD susceptibility, progression and exacerbations. These include cigarette smoking, environmental and occupational pollutants, respiratory infections and comorbidities. As the clinical phenotypes of COPD are so variable, it has been difficult to devise an individualized treatment plan for patients with this complex chronic disease. This review will highlight how potential clinical, inflammatory, genomic and epigenomic biomarkers for COPD could be used to personalize treatment, leading to improved disease management and prevention for our patients
Green engineering: Integration of green chemistry, pollution prevention, and risk-based considerations
Literature sources on green chemistry and green engineering are numerous. The objective of this chapter is to familiarize readers with some of the green engineering and chemistry concepts, approaches, and tools. In order to do this, the chapter is organized into five sections as follows