97 research outputs found

    Toward a mode reduction strategy in shallow moist convection

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    The insufficient parameterization of low clouds which are caused by shallow convection remains one of the biggest sources of uncertainty in large-scale models of global atmospheric motion. One way to overcome this lack of understanding is to develop Boussinesq models of moist convection with simplified thermodynamics which allow for systematic studies of the cloud formation in different dynamical regimes and depend on a small set of system parameters only. This route makes the problem accessible to direct numerical simulations of turbulence without subgrid-scale modeling and provides an ideal testing bed for systematic and stepwise reductions of degrees of freedom. Such systematic reductions are studied here for a recently developed moist Rayleigh-Bénard convection model in the conditionally unstable regime. Our analysis is based on the proper orthogonal decomposition (POD) and determines the corresponding modes by a direct solution of the eigenvalue problem in form of an integral equation. The resulting reduced-order dynamical systems are obtained by a projection of the original equations of motion onto a finite set of POD modes. These modes are selected with respect to their energy as well as their ability to transport energy from large to small scales and to dissipate the energy at smaller scales efficiently such that an additional modal viscosity can be omitted for most cases. The reduced models reproduce important statistical quantities such as cloud cover, liquid water flux and global buoyancy transport to a very good degree. Furthermore we investigate different pathways to reduce the number of degrees of freedom in the low-dimensional models. The number of degrees of freedom can be compressed by more than two orders of magnitude until the models break down and cause significant deviations of essential mean transport quantities from the original fully resolved simulation data. © IOP Publishing and Deutsche Physikalische Gesellschaft

    Effect of Different Collegiate Sports on Cortical Bone in the Tibia

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    Objectives: The purpose of this study was to determine the effect of sports participation on cortical bone in the tibia. Methods: 53 female collegiate athletes (25 cross-country, 16 soccer, and 12 volleyball) and 20 inactive controls had the left distal 20% tibia scanned by pQCT. Cortical volumetric BMD (vBMD) was measured within the cortical shell at the anterior, posterior, medial, and lateral regions and standard deviations were calculated. Results: Total vBMD was greater in the control group (1161±5 mg/mm3) than each of the sports (p\u3c0.05). Soccer players (1147±5 mg/mm3) had greater vBMD than volleyball players (1136±7 mg/mm3) (p\u3c0.05), but similar to cross-country runners (1145±5 mg/mm3). Cortical thickness was greatest in soccer players (4.1±0.1 mm), while cross-country and control subjects (3.8±0.1 mm) had greater thickness than volleyball players (3.4±0.1 mm)(p\u3c0.05). Periosteal circumference was greater in volleyball players (71±1.4 mm) than soccer, cross-country, and control subjects (68±0.9, 69±0.8, and 66±1 mm, respectively; all, p\u3c0.05). vBMD variation within the cortical shell was greater among control subjects (70±6 mg/cm3) than each of the athlete groups, with soccer players having lower variation than cross country runners (within-in person SD 36±6 mg/cm3 and 54±5 mg/cm3 respectively; p\u3c0.05). Conclusion: These results indicate bone geometry and distribution within the cortical shell of the tibia varies depending upon sporting activities of young women

    Sclerostin: Current Knowledge and Future Perspectives

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    In recent years study of rare human bone disorders has led to the identification of important signaling pathways that regulate bone formation. Such diseases include the bone sclerosing dysplasias sclerosteosis and van Buchem disease, which are due to deficiency of sclerostin, a protein secreted by osteocytes that inhibits bone formation by osteoblasts. The restricted expression pattern of sclerostin in the skeleton and the exclusive bone phenotype of good quality of patients with sclerosteosis and van Buchem disease provide the basis for the design of therapeutics that stimulate bone formation. We review here current knowledge of the regulation of the expression and formation of sclerostin, its mechanism of action, and its potential as a bone-building treatment for patients with osteoporosis

    Alloplastische Implantate in der Kopf- und Halschirurgie.

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    New perspectives in turbulent Rayleigh-Bénard convection

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