Clinical surveillance of thrombotic microangiopathies in Scotland, 2003-2005

The prevalence, incidence and outcomes of haemolytic uraemic syndrome (HUS) and thrombotic thrombocytopaenic purpura (TTP) are not well established in adults or children from prospective studies. We sought to identify both outcomes and current management strategies using prospective, national surveillance of HUS and TTP, from 2003 to 2005 inclusive. We also investigated the links between these disorders and factors implicated in the aetiology of HUS and TTP including infections, chemotherapy, and immunosuppression. Most cases of HUS were caused by verocytotoxin-producing Escherichia coli (VTEC), of which serotype O157 predominated, although other serotypes were identified. The list of predisposing factors for TTP was more varied although use of immunosuppressive agents and severe sepsis, were the most frequent precipitants. The study demonstrates that while differentiating between HUS and TTP is sometimes difficult, in most cases the two syndromes have quite different predisposing factors and clinical parameters, enabling clinical and epidemiological profiling for these disorders

Overcoming errors: A closer look at the attributional mechanism

We extend the knowledge about the causal attribution mechanism by investigating the roles of causal ascription (stability and locus of causality) and causal interpretation (personal control and responsibility) after error occurrence. One hundred twenty-five participants were randomly assigned to one of four experimental conditions (internal vs. external by unstable vs. stable attribution instructions). Internal unstable ascriptions lead to higher perceived control after error occurrence. Both control and responsibility, in turn, predict task behavior. While causal interpretation predicts outcome measures, causal ascriptions are related to the same measures only indirectly. Implications for research and practice are discussed. © Springer Science+Business, LCC 2007

Support of generalized parton distributions in Bethe-Salpeter models of hadrons

The proper support of generalized parton distributions from relativistic constituent quark models with pointlike constituents is studied. The correct support is guaranteed when the vertex function does not depend on the relative minus-momentum. We show that including quark interactions in models with pointlike constituent quarks might lead to a support problem. A computation of the magnitude of the support problem in the Bonn relativistic constituent quark model is presented.Comment: 8 pages, 4 figures. v2: specific calculation included, references and figure added. Submitted to Phys. Lett.

A Comment on the Topological Phase for Anti-Particles in a Lorentz-violating environment

Recently, a scheme to analyse topological phases in Quantum Mechanics by means of the non-relativistic limit of fermions non-minimally coupled to a Lorentz-breaking background has been proposed. In this letter, we show that the fixed background, responsible for the Lorentz-symmetry violation, may induce opposite Aharonov-Casher phases for a particle and its corresponding antiparticle. We then argue that such a difference may be used to investigate the asymmetry for particle/anti-particle as well as to propose bounds on the associated Lorentz-symmetry violating parameters.Comment: 4 pages - A published versio

Everyone Makes Mistakes - Including Feynman

This talk is dedicated to Alberto Sirlin in celebration of his seventieth birthday. I wish to convey my deep appreciation of his many important contributions to particle physics over 40 years and look forward to many more years of productive research.Comment: 16 pages postscript, also available through http://w4.lns.cornell.edu/public/CLN

N=1 Supersymetric Quantum Mechanics in a Scenario with Lorentz-Symmetry Violation

We show in this paper that the dynamics of a non-relativistic particle with spin, coupled to an external electromagnetic field and to a background that breaks Lorentz symmetry, is naturally endowed with an N=1-supersymmetry. This result is achieved in a superspace approach where the particle coordinates and the spin degrees of freedom are components of the same supermultiplet.Comment: 6 pages, no figure

CPT and Lorentz Tests in Penning Traps

A theoretical analysis is performed of Penning-trap experiments testing CPT and Lorentz symmetry through measurements of anomalous magnetic moments and charge-to-mass ratios. Possible CPT and Lorentz violations arising from spontaneous symmetry breaking at a fundamental level are treated in the context of a general extension of the SU(3) x SU(2) x U(1) standard model and its restriction to quantum electrodynamics. We describe signals that might appear in principle, introduce suitable figures of merit, and estimate CPT and Lorentz bounds attainable in present and future Penning-trap experiments. Experiments measuring anomaly frequencies are found to provide the sharpest tests of CPT symmetry. Bounds are attainable of approximately $10^{-20}$ in the electron-positron case and of $10^{-23}$ for a suggested experiment with protons and antiprotons. Searches for diurnal frequency variations in these experiments could also limit certain types of Lorentz violation to the level of $10^{-18}$ in the electron-positron system and others at the level of $10^{-21}$ in the proton-antiproton system. In contrast, measurements comparing cyclotron frequencies are sensitive within the present theoretical framework to different kinds of Lorentz violation that preserve CPT. Constraints could be obtained on one figure of merit in the electron-positron system at the level of $10^{-16}$, on another in the proton-antiproton system at $10^{-24}$, and on a third at $10^{-25}$ using comparisons of $H^-$ ions with antiprotons.Comment: 31 pages, published in Physical Review

A new photon recoil experiment: towards a determination of the fine structure constant

We report on progress towards a measurement of the fine structure constant to an accuracy of $5\times 10^{-10}$ or better by measuring the ratio of the Planck constant to the mass of the cesium atom. Compared to similar experiments, ours is improved in three significant ways: (i) simultaneous conjugate interferometers, (ii) multi-photon Bragg diffraction between same internal states, and (iii) an about 1000 fold reduction of laser phase noise to -138 dBc/Hz. Combining that with a new method to simultaneously stabilize the phases of four frequencies, we achieve 0.2 mrad effective phase noise at the location of the atoms. In addition, we use active stabilization to suppress systematic effects due to beam misalignment.Comment: 12 pages, 9 figure