8,422 research outputs found
Immune reconstitution inflammatory syndrome in children
Paradoxical deterioration due to immune reconstitution inflammatory syndrome (IRIS) occurs in up to 21% of children initiating antiretroviral therapy. Mycobacterial diseases are the most common, with BCG-vaccine adenitis predominating in infants and Mycobacterium tuberculosis (TB) in older children. The difficulty of diagnosing TB in HIV-infected children and the increasing risk of drug-resistant TB complicate the diagnosis and management of both paradoxical IRIS and post-antiretroviral therapy TB. History and clinical assessment remain key strategies in the management of these infants and children. There are no prospective studies investigating diagnostic criteria and therapeutic strategies in children
Anisotropic softening of magnetic excitations in lightly electron doped SrIrO
The magnetic excitations in electron doped (SrLa)IrO with
were measured using resonant inelastic X-ray scattering at the Ir
-edge. Although much broadened, well defined dispersive magnetic
excitations were observed. Comparing with the magnetic dispersion from the
parent compound, the evolution of the magnetic excitations upon doping is
highly anisotropic. Along the anti-nodal direction, the dispersion is almost
intact. On the other hand, the magnetic excitations along the nodal direction
show significant softening. These results establish the presence of strong
magnetic correlations in electron doped SrLa)IrO with close
analogies to the hole doped cuprates, further motivating the search for high
temperature superconductivity in this system
Plastic Deformation in Laser-Induced Shock Compression of Monocrystalline Copper
Copper monocrystals were subjected to shock compression at pressures of 10–60 GPa by a short (3 ns initial) duration laser pulse. Transmission electron microscopy revealed features consistent with previous observations of shock-compressed copper, albeit at pulse durations in the µs regime. The results suggest that the defect structure is generated at the shock front. A mechanism for dislocation generation is presented, providing a realistic prediction of dislocation density as a function of pressure. The threshold stress for deformation twinning in shock compression is calculated from the constitutive equations for slip, twinning, and the Swegle-Grady relationship
Parental bonding, adult attachment, and theory of mind: A developmental model of alexithymia and alcohol-related risk
Nanostructures in Ti processed by severe plastic deformation
Metals and alloys processed by severe plastic deformation (SPD) can demonstrate superior mechanical properties, which are rendered by their unique defect structures. In this investigation, transmission electron microscopy and x-ray analysis were used to systematically study the defect structures, including grain and subgrain structures, dislocation cells, dislocation distributions, grain boundaries, and the hierarchy of these structural features, in nanostructured Ti produced by a two-step SPD procedure-warm equal channel angular pressing followed by cold rolling. The effects of these defect structures on the mechanical behaviors of nanostructured Ti are discussed
Doping Dependence of Collective Spin and Orbital Excitations in Spin 1 Quantum Antiferromagnet LaSrNiO Observed by X-rays
We report the first empirical demonstration that resonant inelastic x-ray
scattering (RIXS) is sensitive to \emph{collective} magnetic excitations in
systems by probing the Ni -edge of LaSrNiO (). The magnetic excitation peak is asymmetric, indicating the
presence of single and multi spin-flip excitations. As the hole doping level is
increased, the zone boundary magnon energy is suppressed at a much larger rate
than that in hole doped cuprates. Based on the analysis of the orbital and
charge excitations observed by RIXS, we argue that this difference is related
to the orbital character of the doped holes in these two families. This work
establishes RIXS as a probe of fundamental magnetic interactions in nickelates
opening the way towards studies of heterostructures and ultra-fast pump-probe
experiments.Comment: 8 pages, 4 figures, see ancillary files for the supplemental materia
Systems Theory as the Foundation for Understanding Systems
As currently used, systems theory is lacking a universally agreed upon definition. The purpose of this paper is to offer a resolution by articulating a formal definition of systems theory. This definition is presented as a unified group of specific propositions which are brought together by way of an axiom set to form a system construct: systems theory. This construct affords systems practitioners and theoreticians with a prescriptive set of axioms by which a system must operate; conversely, any set of entities identified as a system may be characterized by this set of axioms. Given its multidisciplinary theoretical foundation and discipline-agnostic framework, systems theory, as it is presented here, is posited as a general approach to understanding system behavior. © 2013 Wiley Periodicals, Inc
LOFAR early-time search for coherent radio emission from GRB 180706A
© 2019 The Author(s) Published by Oxford University Press on behalf of the Royal Astronomical Society.The nature of the central engines of gamma-ray bursts (GRBs) and the composition of their relativistic jets are still under debate. If the jets are Poynting flux dominated rather than baryon dominated, a coherent radio flare from magnetic re-connection events might be expected with the prompt gamma-ray emission. There are two competing models for the central engines of GRBs; a black hole or a newly formed milli-second magnetar. If the central engine is a magnetar it is predicted to produce coherent radio emission as persistent or flaring activity. In this paper, we present the deepest limits to date for this emission following LOFAR rapid response observations of GRB 180706A. No emission is detected to a 3 limit of 1.7 mJy beam at 144 MHz in a two-hour LOFAR observation starting 4.5 minutes after the gamma-ray trigger. A forced source extraction at the position of GRB 180706A provides a marginally positive (1 sigma) peak flux density of mJy. The data were time-sliced into different sets of snapshot durations to search for FRB like emission. No short duration emission was detected at the location of the GRB. We compare these results to theoretical models and discuss the implications of a non-detection.Peer reviewedFinal Accepted Versio
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