29,189 research outputs found

    World Health Organization (WHO)/International Society of Urological Pathology (ISUP) grading in fine‐needle aspiration biopsies of renal masses

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    Background Utilization of fine‐needle aspiration (FNA) biopsy for the evaluation of renal masses has been increasing at our institution. At times diagnostic material on direct smears is superior to that in the cell block/core biopsy, therefore assigning an accurate nuclear grade in the cytopathology report would provide useful prognostic information. Methods Search of the pathology database identified renal FNAs performed during an 11‐year period (2006–2017). Corresponding core biopsies and resections were identified. Cases with a diagnosis of primary renal neoplasia on FNA, core biopsy, and/or resection were included. Two pathologists reviewed all cases and assigned a World Health Organization (WHO)/International Society of Urological Pathology (ISUP) grade to each FNA, core biopsy, and resection case. Results A total of 162 kidney FNAs were identified. Primary renal neoplasia was diagnosed in 137 cases on core biopsy/resection. Among diagnostic FNAs of clear cell RCC and papillary RCC with core biopsy/resection specimens for re‐review (n = 52), reviewers assigned a concordant WHO/ISUP grade to 83% (43/52) of cases. Among 9 cases with discrepant scores, all had a discrepancy of 1 grade and were undergraded on FNA. Using a two tier grading system (low vs. high grade), reviewers assigned a concordant grade to 88% (46/52) of cases. Among 6 cases with discrepant scores, all were classified as low grade (WHO/ISUP grade 2) on FNA versus high grade (WHO/ISUP grade 3) on resection. Conclusion The WHO/ISUP grade assigned on FNA shows good concordance with subsequent resection/core specimens (83%), with all discrepant cases being undergraded by one grade

    Globalisation and the Inward Flow of Immigrants: Issues Associated with the Inpatriation of Global Managers

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    Cataloged from PDF version of article.Assembling a diverse global workforce is becoming a critical dimension in gaining successful global performance. In the past, staffing has focused on control of the multinational organization as the primary goal when staffing overseas positions. As organizations globalize their operations, the goal of staffing is shifting from control to diversity, which in turn will provide the global organization with a means to gain/maintain competitive advantage. This diversity will be accomplished by integrating foreigners into the home country organization (i.e., inpatriation) through a permanent assignment. This article examines the inward flow of inpatriate managers by using social learning theory as a lens to better understand the means to integrate foreign managers into the domestic organization culture. The stages that inpatriate managers will go through (i.e., survival, integration, acculturation, and pluralistic integration) are explored to ascertain how to effectively utilize these global managers. © 2011 Wiley Periodicals, Inc.

    The Self-Dual String and Anomalies in the M5-brane

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    We study the anomalies of a charge Q2Q_2 self-dual string solution in the Coulomb branch of Q5Q_5 M5-branes. Cancellation of these anomalies allows us to determine the anomaly of the zero-modes on the self-dual string and their scaling with Q2Q_2 and Q5Q_5. The dimensional reduction of the five-brane anomalous couplings then lead to certain anomalous couplings for D-branes.Comment: 13 pages, Harvmac, refs adde

    Far-infrared observations of young clusters embedded in the R Coronae Austrinae and RHO Ophiuchi dark clouds

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    Multicolor far infrared maps in two nearby dark clouds, R Coronae Austrinae and rho Ophiuchi, were made in order to investigate the individual contribution of low mass stars to the energetics and dynamics of the surrounding gas and dust. Emission from cool dust associated with five low mass stars in Cr A and four in rho Oph was detected; their far infrared luminosities range from 2 far infrared luminosities L. up to 40 far infrared luminosities. When an estimate of the bolometric luminosity was possible, it was found that typically more than 50% of the star's energy was radiated longward of 20 micrometers. meaningful limits to the far infrared luminosities of an additional eleven association members in Cr A and two in rho Oph were also obtained. The dust optical depth surrounding the star R Cr A appears to be asymmetric and may control the dynamics of the surrounding molecular gas. The implications of the results for the cloud energetics and star formation efficiency in these two clouds are discussed

    On a three-body confinement force in hadron spectroscopy

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    Recently it has been argued that a three-body colour confinement interaction can affect the stability condition of a three-quark system and the spectrum of a tetraquark described by any constituent quark model. Here we discuss the role of a three-body colour confinement interaction in a simple quark model and present some of its implications for the spectra of baryons, tetraquarks and six-quark systems.Comment: 19 pages (RevTeX), addition of new material regarding the NN interaction, more accurate discussion of the baryonic case, accepted for publication in Phys. Rev.

    The Evolving Role of Supply Chain Managers in global Channels of Distribution and Logistics Systems

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    Cataloged from PDF version of article.Purpose – Supply chains have become a strategic strength to many firms due to the nature of the globalization of business. The past roles of supply chain managers have changed dramatically and now also include various new duties that will enhance firm competitiveness due to their boundary spanning nature and the new focus of learning organizations. The paper aims to discuss these issues. Design/methodology/approach – This was a theoretically developed paper exploring trust, learning organizations, and supply chains. Findings – Researchers are now focussing on the relationship among the supply chain network through the paradigm of relational marketing as the governance structures of contractual arrangements globally cannot be anticipated. Originality/value – The research through the lens of relational marketing explores how supply chain managers’ core duties are now compounded by global/cultural nuances in respect to implicit knowledge acquisition and relationship development through strong-form trust

    A Spitzer Search For Planetary-Mass Brown Dwarfs With Circumstellar Disks: Candidate Selection

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    We report on initial results from a Spitzer program to search for very low-mass brown dwarfs in Ophiuchus. This program is an extension of an earlier study by Allers et al. which had resulted in an extraordinary success rate, 18 confirmed out of 19 candidates. Their program combined near-infrared and Spitzer photom- etry to identify objects with very cool photospheres together with circumstellar disk emission to indicate youth. Our new program has obtained deep IRAC pho- tometry of a 0.5 deg2 field that was part of the original Allers et al. study. We report 18 new candidates whose luminosities extend down to 10-4 L\cdot which sug- gests masses down to ~ 2 MJ if confirmed. We describe our selection techniques, likely contamination issues, and follow-on photometry and spectroscopy that are in progress

    Corporate social responsibility: Why bother?

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    Cataloged from PDF version of article.Corporate Social Responsibility (CSR) is not a new concept, but unfortunately has been defined in so many ways, it is often misinterpreted. In fact it has had 40 years to evolve from a somewhat infant concept to a successful managerial tool to build a company's reputation in the global market arena. Corporate social responsibility has become corporate strategic responsibility - an imperative element of corporate global business strategies. Many leaders, entrepreneurs, investors, executives and politicians now recognize CSR's potential for differentiation and positioning in the global marketplace. In the 21st century, we find CSR to have a remarkable acceptance among practicing managers; publicly traded corporations especially label CSR an essential tool for their long-term legitimacy and profitability. CSR has matured from its infancy, becoming a corporate reputational adding value strategy for firms

    MAGMO: Coherent magnetic fields in the star forming regions of the Carina-Sagittarius spiral arm tangent

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    We present the pilot results of the `MAGMO' project, targeted observations of ground-state hydroxyl masers towards sites of 6.7-GHz methanol maser emission in the Carina-Sagittarius spiral arm tangent, Galactic longitudes 280 degrees to 295 degrees. The `MAGMO' project aims to determine if Galactic magnetic fields can be traced with Zeeman splitting of masers associated with star formation. Pilot observations of 23 sites of methanol maser emission were made, with the detection of ground-state hydroxyl masers towards 11 of these and six additional offset sites. Of these 17 sites, nine are new detections of sites of 1665-MHz maser emission, three of them accompanied by 1667-MHz emission. More than 70% of the maser features have significant circular polarization, whilst only ~10% have significant linear polarization (although some features with up to 100% linear polarization are found). We find 11 Zeeman pairs across six sites of high-mass star formation with implied magnetic field strengths between -1.5 mG and +3.8 mG and a median field strength of +1.6 mG. Our measurements of Zeeman splitting imply that a coherent field orientation is experienced by the maser sites across a distance of 5.3+/-2.0 kpc within the Carina-Sagittarius spiral arm tangent.Comment: 19 pages, 13 figures, accepted for publication in MNRA

    Mathieu twining characters for K3

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    The analogue of the McKay-Thompson series for the proposed Mathieu group action on the elliptic genus of K3 is analysed. The corresponding NS-sector twining characters have good modular properties and satisfy remarkable replication identities. These observations provide strong support for the conjecture that the elliptic genus of K3 carries indeed an action of the Mathieu group M24.Comment: 19 page
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