Does the Digital Environment Improve Modern Users\u27 Internet Awareness?

This paper traces users\u27 Internet literacy level by measuring their Library visit and attitude towards the library as a means of access to electronic resources. Modern users\u27 dependence on the Internet increases day by day. The value of any product that exists in the market can be measured in terms of use. The present study revolves around users\u27 frequency of library visits and their Internet awareness levels. The research questions are; do modern users\u27 library visits differ? ; do the users\u27 Internet awareness levels differ? ; do the users\u27 library visits influence them to upgrade their awareness of the Internet

Free Radical Scavenging, Cytotoxic and Hemolytic Activities from Leaves of Acacia nilotica (L.) Wild. ex. Delile subsp. indica (Benth.) Brenan

Dietary intake of phytochemicals having antioxidant activity is associated with a lower risk of mortality from many diseases. Therefore, the aim of this study was to determine the free radical scavenging, cytotoxic and hemolytic activities of leaves of Acacia nilotica by using various methods. The results of the present study revealed that ethanol extract was the most effective and IC50 value was found to be 53.6 μg mL−1 for Vero cell lines and 28.9 μg mL−1 for Hela cell lines in cytotoxicity assays. The zone of color retention was 14.2 mm in β-carotene bleaching assay, which was as significant as positive control, butylated hydroxy toluene. None of the tested extracts possessed any hemolytic activity against rat and human erythrocytes revealing their cytotoxic mechanism and non-toxicity. Thus, only the ethanol extract could be considered as a potential source of anticancer and antioxidant compounds. Further phytochemical studies will be performed for specification of the biologically active principles

PACCE -A Real Genuine Key Swap over Protocols

A Secure protocols for password-based user authentication unit well-studied among the crypto logical literature but have did not see wide-spread adoption on the internet; most proposals up to presently want full modifications to the Transport Layer Security (TLS) protocol, making preparation onerous. Recently many traditional styles square measure projected among that a cryptographically secure countersign-based mutual authentication protocol is run among a confidential (but not primarily authenticated) channel like TLS; the countersign protocol is sure to the established channel to forestall active attacks. Such protocols unit helpful in apply for a ramification of reasons: ability to validate server certificates and can all told likelihood be enforced with no modifications to the secure channel protocol library. It offers a scientific study of such authentication protocols. Building on recent advances in modelling TLS, we've associate inclination to provide a correct definition of the meant security goal, that we've associate inclination to decision password-authenticated and confidential channel institution (PACCE). we've associate inclination to imply generically that combining a secure channel protocol, like TLS, Our prototypes supported TLS unit accessible as a cross-platform client-side Firefox browser extension furthermore as associate golem application and a server-side internet application which will simply be place in on servers

Sexually transmitted infections among men who have sex with men: a retrospective study in a tertiary care hospital

Background: Men who have sex with Men (MSM) have a higher prevalence of HIV and other sexually transmitted infections (STI) than the heterosexual men. In India, NACP recommendations to reduce HIV prevalence among MSM include early detection of HIV and other STI by screening and treatment. We conducted a study of STIs among MSM attending our OPD. The aim of the study was to assess the prevalence of STIs in MSM attending our OPD.Methods: 1215 MSM among 9008 patients who attended our OPD between June 2015 and May 2016 were included in the study. Detailed history was taken and clinical examination carried out. Urethral discharge and urine samples were tested for Gonococcal infection. Smears from ulcers were tested for Syphilis, Chancroid, Herpes and Donovanosis. Serum samples were tested for HIV and other STIs like Syphilis and Herpes.Results: Among 1215 MSMs, 55 (4.5%) tested positive for VDRL and TPHA and 33 (2.7%) tested positive for HIV. 24 (2%) had urethritis (10 GU and 14 NGU), 15 (1.25%) had Balanophosthitis, 12 (1%) had genital herpes, 9 (0.75%) had genital scabies, 6 (0.5%) had Genital Wart and 2 (0.16%) had Molluscum contagiosum. Prevalence of these STIs were far higher in MSMs than in heterosexual men.Conclusions: This study highlights the higher prevalence of STIs among MSMs and the need for early intervention and treatment in this high-risk population

Studies on the Impact of Altitudinal Gradient on Ammonium Assimilatory Metabolism in Glycine max L. (Fabaceae)

Seedlings of Glycine max L. were grown, transplanted and acclimatized for 60 days at different altitudes (250, 400 and 1600 m). Response to shift in altitude was observed in the plants. Shoot length decreased with the increase in the altitude, while root length followed a reverse trend. Biomass accumulation in shoot and roots of G. max was the maximum at high altitude. Total soluble protein content was significantly high at low altitude in the shoot and the roots. Free tissue ammonia level in this species showed positive correlation with increasing altitude. Ammonium assimilatory enzymes viz., glutamine synthetase (GS), glutamate synthase (GOGAT) and glutamate dehydrogenase (GDH) were studied. GS/ GOGAT specific and total activity were altitude sensitive, whereas GDH activity exhibited inverse trend. Results indicate that there is a positive shift in ammonium assimilatory pathway in plants growing at high altitude

Impact of Altitudinal Gradient on Ammonium Assimilatory Enzymes in Rauvolfia teraphylla L. (Apocyanaceae) – A Perennial Medicinal Herb

Seedlings of Ravuolfia tetraphylla L. were grown, transplanted and acclimatized for 60 days at different altitudes gradient (250, 400 and 1600 m) in Yercaud, Salem, Tamil Nadu, India. Response to shift in altitude was observed in the test plants. Shoot length decreased with the increase in the altitude, while increase in the root length was directly proportional to the increase in the altitudinal gradient. Biomass accumulation in roots of R. tetraphylla recorded the maximum at high altitude at the same time shoot biomass was maximum at an intermediate height (400m), thereafter reduction in biomass was observed with the increase in the altitude. Total soluble protein content was significantly high at low altitude in the shoot while it followed a reverse trend in the roots. Likewise, free tissue ammonia level in this species showed positive correlation with increase in the altitude. Ammonium assimilatory enzymes viz., glutamine synthetase (GS), glutamate synthase (GOGAT) and glutamate dehydrogenase (GDH) were analyzed. GS/ GOGAT activity and specific activity were altitude sensitive, whereas GDH activity exhibited inverse trend. A positive shift in ammonium assimilatory pathway in test plants growing at high altitude was observed in R. tetraphylla

Investigations on Hepatoprotective Activity of Leaf Extracts of Aegle marmelos (L.) Corr. (Rutaceae)

The present study was carried out to screen and evaluate the hepatoprotective activity of leaf extracts of Aegle marmelos (L.) Corr. Hepatoprotective activities of ethanolic and aqueous extracts of A. marmelos were examined against carbon tetrachloride induced liver damage in mice using silymarin as control. Enzyme activities of Serum Glutamate Oxaloacetate Transaminase (SGOT), Serum Glutamate Pyruvate Transaminase (SGPT) and Alkaline Phosphatase (ALP) were analyzed. Results indicate that ethanolic and aqueous leaf extracts of A. marmelos had moderate activity over carbon tetrachloride treatment as compared to control. Results of the present investigation confirm the traditional uses of this plant as a potential hepatoprotective agent

Studies on Hepatoprotective Properties of Leaf Extracts of Azadirachta indica A. Juss (Meliaceae)

The present study was carried out to evaluate the hepatoprotective role of leaf extracts of Azadirachta indica A. Juss. Hepatoprotective activities of ethanolic and aqueous extracts of A. indica were examined against carbon tetrachloride induced liver damage in mice using silymarin as control. Enzyme activities of Serum Glutamate Oxaloacetate Transaminase (SGOT), Serum Glutamate Pyruvate Transaminase (SGPT) and Alkaline Phosphatase (ALP) were analyzed. Phytochemical leaf extracts of A. indica exhibited significant hepatoprotective activity. Ethanolic and aqueous leaf extracts of A. indica exhibited moderate activity over carbon tetrachloride treated animals. Results confirm the traditional - ethnomedicinal use of A. indica as a potential source of hepatoprotective agent

Low-temperature anomalies in muon spin relaxation of solid and hollow nanoparticles: a pathway to detect unusual local spin dynamics

By means of muon spin relaxation measurements we unraveled the temperature spin dynamics in monodisperse maghemite spherical nanoparticles with different surface to volume ratio, in two samples with a full core (diameter D∼4 and D∼5nm) and one with a hollow core (external diameter D∼7.4nm). The behavior of the muon longitudinal relaxation rates as a function of temperature allowed us to identify two distinct spin dynamics. The first is well witnessed by the presence of a characteristic peak for all the samples around the so-called muon blocking temperature T$_{B}^{μ+}$. A Bloembergen-Purcell-Pound (BPP)-like model reproduces the experimental data around the peak and at higher temperatures (20<T<100K) by assuming the Néel reversal time of the magnetization as the dominating correlation time. An additional dynamic emerges in the samples with higher surface to volume ratio, namely, full 4 nm and hollow samples. This is witnessed by a shoulder of the main peak for T<20K at low longitudinal field (μ$_{0}$H≈15mT), followed by an abrupt increase of the relaxation rate at T<10K, which is more evident for the hollow sample. These unusual anomalies of the longitudinal relaxation rate for T<T$_{B}^{μ+}$ are suggested to be due to the surface spins’ dynamical behavior. Furthermore, for weak applied longitudinal magnetic field (μ$_{0}$H≈15mT) and T<T$_{B}^{μ+}$ we observed damped coherent oscillations of the muon asymmetry, which are a signature of a quasistatic local field at the muon site as probed by muons implanted in the inner magnetic core of the nanoparticles. The muon spin relaxation technique turns out to be very successful to study the magnetic behavior of maghemite nanoparticles and to detect their unusual local spin dynamics in low magnetic field conditions

Underlying Factors Associated with Anemia in Amazonian Children: A Population-Based, Cross-Sectional Study

Background: Although iron deficiency is considered to be the main cause of anemia in children worldwide, other contributors to childhood anemia remain little studied in developing countries. We estimated the relative contributions of different factors to anemia in a population-based, cross-sectional survey. Methodology: We obtained venous blood samples from 1111 children aged 6 months to 10 years living in the frontier town of Acrelandia, northwest Brazil, to estimate the prevalence of anemia and iron deficiency by measuring hemoglobin, erythrocyte indices, ferritin, soluble transferrin receptor, and C-reactive protein concentrations. Children were simultaneously screened for vitamin A, vitamin B-12, and folate deficiencies; intestinal parasite infections; glucose-6-phosphate dehydrogenase deficiency; and sickle cell trait carriage. Multiple Poisson regression and adjusted prevalence ratios (aPR) were used to describe associations between anemia and the independent variables. Principal Findings: The prevalence of anemia, iron deficiency, and iron-deficiency anemia were 13.6%, 45.4%, and 10.3%, respectively. Children whose families were in the highest income quartile, compared with the lowest, had a lower risk of anemia (aPR, 0.60; 95% CI, 0.37-0.98). Child age (&lt;24 months, 2.90; 2.01-4.20) and maternal parity (&gt;2 pregnancies, 2.01; 1.40-2.87) were positively associated with anemia. Other associated correlates were iron deficiency (2.1; 1.4-3.0), vitamin B-12 (1.4; 1.0-2.2), and folate (2.0; 1.3-3.1) deficiencies, and C-reactive protein concentrations (&gt;5 mg/L, 1.5; 1.1-2.2). Conclusions: Addressing morbidities and multiple nutritional deficiencies in children and mothers and improving the purchasing power of poorer families are potentially important interventions to reduce the burden of anemia.Sao Paulo State Research Agency [FAPESP 07/53042-1]Sao Paulo State Research AgencyNational Research Agency of BrazilNational Research Agency of Brazil [CNPq 470573/2007-4