Brief Notice on T. H. Lewin’s Visit to the Arakan Hills in 1865-1866, edited by Michael W. Charney

This notice was originally published as “Diary of a Hill-Trip on the Borders of Arracan. By Lieutenant T. H. Lewis” in 1867. Edited by Michael W. Charney for the SOAS Bulletin of burma Research

Synthesis and Reactivity of Iridium(III) Dihydrido Aminocarbenes

Iridium complexes supported by the PNP amidophosphine scaffold (PNP = [N(2-PiPr2-4-Me-C6H3)2]−) perform the selective double C−H activation of methyl amines to produce iridium(III) dihydrido aminocarbenes. The reactivity of these complexes is presented and contrasted with that observed for the previously reported iridium(I) alkoxycarbenes

Genome editing in non-model organisms opens new horizons for comparative physiology

For almost 100 years, biologists have made fundamental discoveries using a handful of model organisms that are not representative of the rich diversity found in nature. The advent of CRISPR genome editing now opens up a wide range of new organisms to mechanistic investigation. This increases not only the taxonomic breadth of current research but also the scope of biological problems that are now amenable to study, such as population control of invasive species, management of disease vectors such as mosquitoes, the creation of chimeric animal hosts to grow human organs and even the possibility of resurrecting extinct species such as passenger pigeons and mammoths. Beyond these practical applications, work on non-model organisms enriches our basic understanding of the natural world. This special issue addresses a broad spectrum of biological problems in non-model organisms and highlights the utility of genome editing across levels of complexity from development and physiology to behaviour and evolution

Organizational Pay Mix: The Implications of Various Theoretical Perspectives for the Conceptualization and Measurement of Individual Pay Components

While pay mix is one of the most frequently used variables in recent compensation research, its theoretical relevance and measurement remains underdeveloped. There is little agreement among studies on the definitions of the various forms of pay that go into pay mix. Even studies that examine the same theories tend to overlook the implications of differences in the measures and meanings of pay mix used in other studies. Our study explores the meaning of pay mix using several theories commonly used in recent compensation research (agency, efficiency wage, expectancy, equity, and person-organization fit). Recent studies generally use a single measure of mix (e.g., bonus/base, or stock options/total, or benefits/base). We argue that to fully understand the effects of employee compensation, the multiple forms of compensation must be taken into account. Therefore, we derived pay mix measures from the theories commonly used in compensation research. We classified the pay mix policies of 478 firms using cluster-analytic techniques. We found that the classification of organizations based on their pay mix depends on the measures used. We suggest that as more realistic measures of pay mix leads to reinterpretation of compensation research and offers directions for theory development

Single Superconducting Split-Ring Resonator Electrodynamics

We investigate the microwave electrodynamic properties of a single superconducting thin film split-ring resonator (SRR). The experiments were performed in an all-Nb waveguide, with Nb wires and Nb SRRs. Transmission data showed a high-Q stopband for a single Nb SRR ($Q \sim 4.5\times10^4$ at 4.2 K) below $T_c$, and no such feature for a Cu SRR, or closed Nb loops, of similar dimensions. Adding SRRs increased the bandwidth, but decreased the insertion loss of the features. Placing the Nb SRR into an array of wires produced a single, elementary negative-index passband ($Q \sim 2.26\times10^4$ at 4.2 K). Changes in the features due to the superconducting kinetic inductance were observed. Models for the SRR permeability, and the wire dielectric response, were used to fit the data.Comment: 4 pages, 3 figures, RevTex, submitted to Applied Physics Letters. Updated version includes mention of bianisotropy, better looking figures, and different temperature dat

Individual differences in pain sensitivity are associated with cognitive network functional connectivity following one night of experimental sleep disruption.

Previous work suggests that sleep disruption can contribute to poor pain modulation. Here, we used experimental sleep disruption to examine the relationship between sleep disruption-induced pain sensitivity and functional connectivity (FC) of cognitive networks contributing to pain modulation. Nineteen healthy individuals underwent two counterbalanced experimental sleep conditions for one night each: uninterrupted sleep versus sleep disruption. Following each condition, participants completed functional MRI including a simple motor task and a noxious thermal stimulation task. Pain ratings and stimulus temperatures from the latter task were combined to calculate a pain sensitivity change score following sleep disruption. This change score was used as a predictor of simple motor task FC changes using bilateral executive control networks (RECN, LECN) and the default mode network (DMN) masks as seed regions of interest (ROIs). Increased pain sensitivity after sleep disruption was positively associated with increased RECN FC to ROIs within the DMN and LECN (F(4,14) = 25.28, pFDR = 0.05). However, this pain sensitivity change score did not predict FC changes using LECN and DMN masks as seeds (pFDR > 0.05). Given that only RECN FC was associated with sleep loss-induced hyperalgesia, findings suggest that cognitive networks only partially contribute to the sleep-pain dyad

Machine aided indexing from natural language text

The NASA Lexical Dictionary (NLD) Machine Aided Indexing (MAI) system was designed to (1) reuse the indexing of the Defense Technical Information Center (DTIC); (2) reuse the indexing of the Department of Energy (DOE); and (3) reduce the time required for original indexing. This was done by automatically generating appropriate NASA thesaurus terms from either the other agency's index terms, or, for original indexing, from document titles and abstracts. The NASA STI Program staff devised two different ways to generate thesaurus terms from text. The first group of programs identified noun phrases by a parsing method that allowed for conjunctions and certain prepositions, on the assumption that indexable concepts are found in such phrases. Results were not always satisfactory, and it was noted that indexable concepts often occurred outside of noun phrases. The first method also proved to be too slow for the ultimate goal of interactive (online) MAI. The second group of programs used the knowledge base (KB), word proximity, and frequency of word and phrase occurrence to identify indexable concepts. Both methods are described and illustrated. Online MAI has been achieved, as well as several spinoff benefits, which are also described