Ethnomedicine Against Jaundice Used by Gond Tribes of Adilabad District, Andhra Pradesh, India

The present investigation was performed in order to enumerate the medicinal plants that gond tribes uses for the treatment of jaundice in Adilabad district, Andhra Pradesh, India. The study revealed that totally 12 plants belonging to 9 families were used to cure jaundice . The plants were used either separately or in combination with some other plant parts.

Lichens: a novel and potential source as antimicrobials for human use

The use of lichens in medicine is based on the fact that they contain unique and varied biologically active substances, as antimicrobials.  Since they are natural antibiotics, their metabolites exert a wide variety of biological actions including antimycotic, antiviral, anti-inflammatory, analgesic, antipyretic, antiproliferative, and cytotoxic effects, they are considered as potential drugs. They contain a variety of secondary metabolites with strong antioxidant activity. These are substances which have high ability to scavenge toxic free radicals due their phenolic groups. These manifold activities of lichen metabolites have now been recognized, and therefore their therapeutic potential have great impact in pharma industries. The present article discusses the importance of lichens in inhibiting various types of human pathogens in addition to their chemical composition and pharmacological activities

Email Classification Using Adaptive Ontologies Learning

Email is a way of communication for the today’s internet world, private and government sector or public sector all are used email for communication with their clients. They can freely send number of mail to their client without disturbing them. Now a day email communication is also a way of advertising, some mail is also spam, lots of social mails are there. Categorization and handling lots of email is an important task for the researches, as they all are working in this field by using the Natural language processing and ontology extraction process. User get frustrated for handling lots of mails and reading those for finding there is any important mail, sometime user delete lots of mail without reading and in that case may be some important mail which contain the important information may be about meeting, seminar etc. is also deleted. For avoiding these scenarios here auto updation of schedule calendar procedure is proposed by the author. Concept extraction and clustering of concept is done based on fuzzy logic, similar mail pattern is grouped in a same cluster if similarity is less than threshold value a new cluster is defined for that. From the extracted concept author establish the relationship between them and generate the result. Computation overhead is also calculated for different set of mails and finds that it takes very less time in computing large email data set

HIV-I Protease Based Inhibitor Discovery

We can devise a drug (inhibitor) to restrain the activity of gene. As a gene engenders protein/enzyme, so to circumvent the development of any disease causing proteins, we have to stop the activity of that gene. With the aid of different bioinformatics tools and software’s we can do this. A protease is an enzyme that smites proteins to their constituent peptides. The HIV-I Protease (PR) hydrolyses viral polyproteins into functional protein products that are vital for viral assembly and subsequent activity. HIV-I protease activity is decisive for the terminal maturation of infectious virions. Once HIV enters the cell, viral RNA experiences reverse transcription to generate double-stranded DNA (a step inhibited by nucleoside analogues such as zidovudine, didanosine, zalcitabine, stavudine, and lamivudine). In the presence of HIV-I protease inhibitors, the virion is incapable to mature and is quickly cleared by inadequately comprehended mechanisms. Figure 1, left, is a photomicrograph of normal budding virions from an infected cell, while Figure 1, right, determines the effect of bathing these cells with the protease inhibitor, saquinavir. The consequent lack of a dense core for these "ghosted" particles is the feature of noninfectious HIV virions. By applying ncbi we can acquire the nucleotide and protein sequence of HIV-I Protease. By tool and softwares like pfam, clustalw, gold, blast, we designed the inhibitor “SKF 108737”for HIV-I protease. Keywords: Inhibitor (Drug), HIV-I proteas

Design and Implementation of High Speed Bi-directional Transceiver for Low Power Applications

In this paper, a new bi-directional transceiver has been proposed for high speed signaling. The new proposed transceiver architecture has two modes of operation namely, the transmitter and the receiver. Transceiver on either side supports two way communications via same link. Since high transimpedance gain over a large bandwidth in the receiving mode, the signaling current can be reduced to a very low value. The proposed circuit is designed in 90nm technology with the supply voltage of 1.8V

A Dynamic Parallel and Pipelined Architecture for Intra Prediction in H.265 Standard

In the present world where technology is growing faster, the video based applications are rapidly increasing and needs a technology which supports high resolution videos. High Efficiency Video Coding (HEVC) method is one which works on 4K and 8K video applications. In this work we have implemented the new parallel and a hardware accelerator which is highly efficient for the intra prediction blocks. Due to parallel and pipelined architecture, Intra Prediction speeds up the process of prediction and also minimizes the time required for accessing the data from the memory. The given architecture design reduces Area, Power and Delay elements. The results when compared with different FPGA versions shows that our architecture consumes 69 LUTs in ZYNQ FPGA for 4X4 pixels

A second look at the toric h-polynomial of a cubical complex

We provide an explicit formula for the toric $h$-contribution of each cubical shelling component, and a new combinatorial model to prove Clara Chan's result on the non-negativity of these contributions. Our model allows for a variant of the Gessel-Shapiro result on the $g$-polynomial of the cubical lattice, this variant may be shown by simple inclusion-exclusion. We establish an isomorphism between our model and Chan's model and provide a reinterpretation in terms of noncrossing partitions. By discovering another variant of the Gessel-Shapiro result in the work of Denise and Simion, we find evidence that the toric $h$-polynomials of cubes are related to the Morgan-Voyce polynomials via Viennot's combinatorial theory of orthogonal polynomials.Comment: Minor correction

Random routing scheme with misleading dead ends

A new method of sink location security in a Wireless Sensor Network is proposed. In the proposed scheme, all the node addresses are encrypted and an attacker cannot determine the real sink address by capturing the packets and analyzing its contents for the final destination. The main contribution of our proposed method is to use random routing scheme with misleading dead ends. This provides security against traffic analysis attack

ANTIOXIDANT ACTIVITY AND HEPATOPROTECTIVE POTENTIAL OF BALANITES ROXBURGHII FRUITS

ABSTRACTObjectives: The objective of the present study was to evaluate antioxidant activity and hepatoprotective potential of a hydroalcoholic extract ofBalanites roxburghii (BR) fruits.Methods: Extraction was performed by triple maceration using ethanol:water as a solvent. The extracts were vaporated using rotavapor. Thenantioxidant capacities were tested using superoxide, hydroxyl, and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals. Determination of hepatoprotectivemodel was performed by thiocetamide induced liver models.Results: The hydroalcoholic extract of BR fruits produced a dose-dependent percentage inhibition on tested free radicals, i.e., superoxide anion(50% inhibition concentrations [IC50] value 190.50 μg/ml), hydroxyl radical (IC50 value 266.30 μg/ml), and DPPH radical (IC50 value 175 μg/ml). Aftertreatment with silymarin and hydroalcoholic extract of BR in respective groups, they had showed good protection against thioacetamide induced livertoxicity.Conclusion: The results of the present investigation clearly indicate the free radical scavenging activity and hepatoprotective potential of ahydroalcoholic extract of BR fruits and this activity is comparable with that of the standard drugs ascorbic acid and silymarin.Keywords: Balanites roxburghii, Antioxidant activity, Hepatoprotective activity, Ascorbic acid