32 research outputs found

    Studies on termite hill and lime as partial replacement for cement in plastering

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    This study investigated the compressive strength and water absorption capacity of 50�50�50mm mortar cubes made from mixes containing lime, termite hill and cement and sand.Two mix ratios (1:4 and 1:6) and varying binder replacements of cement with lime or termite hill amounting to 0%, 10%, 20%, 30%, 40% and 50% were used.Test results showed that the compressive strength of the mortar cubes increases with age and decreases with increasing percentage replacement of cement with lime and termite hill.However, for mix ratio 1:6, up to 20% replacement of cement with either lime or termite hill, all the mortar cubes had the same strength; subsequently, the termite hill exhibited a higher compressive strength.For mix ratio 1:4, mortar cubes made from lime/cement and termite hill/cement mixtures had the same strength at 50% replacement.Generally, water absorption is higher in mixtures containing lime (18.10% and 14.20% for mix ratios 1:6 and 1:4, respectively, both at 50% replacement level) than those containing termite hill (16.10% and 13.02% for mix ratios 1:6 and 1:4, respectively, both at 50% replacement level). Termite hills seem to be promising as a suitable, locally available housing material for plastering. r 2005 Elsevier Ltd.All rights reserved

    Population, seasonal abundance, Dockovdia oruensis infection and other parasites of Potadoma moerchi in southwestern Nigeria

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    Dockovdia oruensis and some other infections were studied in relation to the population and seasonal abundance of Potadoma moerchi from three streams in a town endemic for schistosomiasis in IjebuNorth, southwestern Nigeria from November 2002 to October 2003. 72.9% of the total 958 specimens of P. moerchi collected were from Eri-Oru Stream. 55.6% and 100% of the snails from Eri-Oru and Ojupon, respectively, were recorded during dry season. 21.3% of the P. moerchi had D. oruensis infection. Eri-Oru had the highest monthly frequency of D. oruensis infection. P. moerchi specimens in 35 -45 mm size class had the highest prevalence of D. oruensis infection. Intensity of infection ranged from one to 12 mites/snail. One (0.8%) of the P. moerchi specimens in 25 - 35 mm size class collected in January 2003 from Eri-Oru had Chaetogaster limnaei infection. 5.9% (15) and 0.1% (1) of the P. moerchi collected from Ojupon and Eri-Oru respectively had trematode infection. 93.8% of the trematode-infected P. moerchi specimens were in 25-35 mm size class

    Role of Low Environmental Temperature in Peptic Ulcer Development

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    Peptic ulcers are described as acid-induced lesions found in the stomach and duodenum caused by the imbalance between the defending factors of the mucosa and the attacking factors such as hydrochloric acid in gastric juice, with Helicobacter Pylori (H. Pylori) and Non-Steroidal Anti-Inflammatory Drugs NSAIDs. They exhibit seasonal patterns in their occurrence, with higher occurrence in winter and spring and a low occurrence in summer. Temperature plays a major role in their occurrence, some of which have resulted in increased morbidity in some number of diseases, such as gastrointestinal bleeding, caused by an increase in air pressure, dry air (relative humidity) occurring from cold air, and also its actions on the protective effect helicobacter pylori in the human body. Their actions excite the adrenal gland marrow and the sympathetic nerve, causing rapid secretion of adrenaline and non-adrenaline, angiotensin II and endothelin, resulting in damage to the mucosa epithelial, caused by the contraction effect of the adrenal agents on the duodenal mucosa and blood vessel. It causes low expression of Epidermal Growth Factor Receptor (EGFR), Epidermal Growth Factor (EGF), Heat Shock Protein (HSP) 70, Occludin, Nitric Oxide Synthase (NOS), in the gastric mucosa, in extremely cold temperature than those in extremely hot temperature, increasing the gastric acid secretion in extremely cold temperature than in extremely hot temperature. Therefore, this review aims to give general insight into the role of low temperature in peptic ulcer development and further consideration in the treatment of peptic ulcer diseases

    Integrated geophysical assessment of a municipal waste disposal site for its geological suitability in terms of the underlain material

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    Dumpsites are major sources of groundwater pollution as a result of leachates that drain out of the decomposed waste. If there are no underlain materials that could serve as a seal to stop the percolation of leachate, it finds its way to the groundwater. A properly designed landfill is expected to have a high leachate curtailment capacity to limit groundwater pollution. A suitable landfill is expected to have a specific thickness of clay which acts as a natural filter. This study aims to determine the subsurface material and the leachate curtailment of Oke–Diya dumpsites. Very low frequency-electromagnetic method was adopted as a reconnaissance survey, after which electrical resistivity and multichannel analysis of surface waves (MASW) methods were carried out. The resistivity values obtained were used to determine the lithological units of the study area while the MASW was employed to determine the seismic wave arrival times which was processed to obtain the shear wave velocities of the subsurface. The rigidity moduli were also obtained from the shear wave velocities, from which the lithological units of the subsurface were inferred. The integrated method appeared to be the ideal tool to characterize the dumpsite and adjudge the leachate curtailment capacity. The methods corroborated each other. Oke-Diya dumpsite, from the results, revealed the study area had low leachate curtailment capacity and should be evacuated

    Validation of the BETA-2 Score: An Improved Tool to Estimate Beta Cell Function After Clinical Islet Transplantation Using a Single Fasting Blood Sample

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    The beta score, a composite measure of beta cell function after islet transplantation, has limited sensitivity because of its categorical nature and requires a mixed‐meal tolerance test (MMTT). We developed a novel score based on a single fasting blood sample. The BETA‐2 score used stepwise forward linear regression incorporating glucose (in millimoles per liter), C‐peptide (in nanomoles per liter), hemoglobin A1c (as a percentage) and insulin dose (U/kg per day) as continuous variables from the original beta score data set (n = 183 MMTTs). Primary and secondary analyses assessed the score's ability to detect glucose intolerance (90‐min MMTT glucose ≥8 mmol/L) and insulin independence, respectively. A validation cohort of islet transplant recipients (n = 114 MMTTs) examined 12 mo after transplantation was used to compare the score's ability to detect these outcomes. The BETA‐2 score was expressed as follows (range 0–42): [Formula: see text] A score <20 and ≥15 detected glucose intolerance and insulin independence, respectively, with >82% sensitivity and specificity. The BETA‐2 score demonstrated greater discrimination than the beta score for these outcomes (p < 0.05). Using a fasting blood sample, the BETA‐2 score estimates graft function as a continuous variable and shows greater discrimination of glucose intolerance and insulin independence after transplantation versus the beta score, allowing frequent assessments of graft function. Studies examining its utility to track long‐term graft function are required

    Congenital hypothyroidism

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    Congenital hypothyroidism (CH) occurs in approximately 1:2,000 to 1:4,000 newborns. The clinical manifestations are often subtle or not present at birth. This likely is due to trans-placental passage of some maternal thyroid hormone, while many infants have some thyroid production of their own. Common symptoms include decreased activity and increased sleep, feeding difficulty, constipation, and prolonged jaundice. On examination, common signs include myxedematous facies, large fontanels, macroglossia, a distended abdomen with umbilical hernia, and hypotonia. CH is classified into permanent and transient forms, which in turn can be divided into primary, secondary, or peripheral etiologies. Thyroid dysgenesis accounts for 85% of permanent, primary CH, while inborn errors of thyroid hormone biosynthesis (dyshormonogeneses) account for 10-15% of cases. Secondary or central CH may occur with isolated TSH deficiency, but more commonly it is associated with congenital hypopitiutarism. Transient CH most commonly occurs in preterm infants born in areas of endemic iodine deficiency. In countries with newborn screening programs in place, infants with CH are diagnosed after detection by screening tests. The diagnosis should be confirmed by finding an elevated serum TSH and low T4 or free T4 level. Other diagnostic tests, such as thyroid radionuclide uptake and scan, thyroid sonography, or serum thyroglobulin determination may help pinpoint the underlying etiology, although treatment may be started without these tests. Levothyroxine is the treatment of choice; the recommended starting dose is 10 to 15 mcg/kg/day. The immediate goals of treatment are to rapidly raise the serum T4 above 130 nmol/L (10 ug/dL) and normalize serum TSH levels. Frequent laboratory monitoring in infancy is essential to ensure optimal neurocognitive outcome. Serum TSH and free T4 should be measured every 1-2 months in the first 6 months of life and every 3-4 months thereafter. In general, the prognosis of infants detected by screening and started on treatment early is excellent, with IQs similar to sibling or classmate controls. Studies show that a lower neurocognitive outcome may occur in those infants started at a later age (> 30 days of age), on lower l-thyroxine doses than currently recommended, and in those infants with more severe hypothyroidism

    Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries.

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    BACKGROUND: As global initiatives increase patient access to surgical treatments, there remains a need to understand the adverse effects of surgery and define appropriate levels of perioperative care. METHODS: We designed a prospective international 7-day cohort study of outcomes following elective adult inpatient surgery in 27 countries. The primary outcome was in-hospital complications. Secondary outcomes were death following a complication (failure to rescue) and death in hospital. Process measures were admission to critical care immediately after surgery or to treat a complication and duration of hospital stay. A single definition of critical care was used for all countries. RESULTS: A total of 474 hospitals in 19 high-, 7 middle- and 1 low-income country were included in the primary analysis. Data included 44 814 patients with a median hospital stay of 4 (range 2-7) days. A total of 7508 patients (16.8%) developed one or more postoperative complication and 207 died (0.5%). The overall mortality among patients who developed complications was 2.8%. Mortality following complications ranged from 2.4% for pulmonary embolism to 43.9% for cardiac arrest. A total of 4360 (9.7%) patients were admitted to a critical care unit as routine immediately after surgery, of whom 2198 (50.4%) developed a complication, with 105 (2.4%) deaths. A total of 1233 patients (16.4%) were admitted to a critical care unit to treat complications, with 119 (9.7%) deaths. Despite lower baseline risk, outcomes were similar in low- and middle-income compared with high-income countries. CONCLUSIONS: Poor patient outcomes are common after inpatient surgery. Global initiatives to increase access to surgical treatments should also address the need for safe perioperative care. STUDY REGISTRATION: ISRCTN5181700

    An integrated national scale SARS-CoV-2 genomic surveillance network

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    A COMPARATIVE STUDY OF SIMULATION AND TIME SERIES MODEL IN QUANTIFYING BULLWHIP EFFECT IN SUPPLY CHAIN

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    Bullwhip (or whiplash) effect is an observed phenomenon in forecast driven distribution channeland careful management of these effects is of great importance to managers of supply chain.Bullwhip effect refers to situations where orders to the suppliers tend to have larger variance thansales to the buyer (demand distortion) and the distortion increases as we move up the supply chain.Due to the fact that demand of customer for product is unstable, business managers must forecast inorder to properly position inventory and other resources. Forecasts are statistically based and in mostcases, are not very accurate. The existence of forecast errors made it necessary for organizations tooften carry an inventory buffer called “safety stock”. Moving up the supply chain from the end userscustomers to raw materials supplier there is a lot of variation in demand that can be observed, whichcall for greater need for safety stock.This study compares the efficacy of simulation and Time Series model in quantifying the bullwhipeffects in supply chain management

    Investigation on the Corrosion Performance of Nickel Electrodeposited Tempered Steel Substrate

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    ABSTRACT The investigation into the corrosion performance of nickel electroplating of low carbon steel substrate in Na 2 CO 3 environment was studied. The substrate was heat treated at various tempering temperatures, plated with nickel for 30 minutes and subjected to corrosion in Na 2 CO 3 solution. The microstructure and weight loss technique were adopted to evaluate the corrosion susceptibility of the substrate Na 2 CO 3 medium. From the results, it was observed that the rate of corrosion of nickel plated tempered low carbon steel substrates is significantly low compared to the control (i.e unplated) sample, couple with the good mechanical properties of the steel confirmed it a good option for engineering applications
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