A multi-pressure analysis of ecosystem services for conservation planning in the Alps

Increasing anthropogenic pressures such as pollution, climate change or invasive species can have multiple impacts on ecosystems and the services (ES) they provide. To address the potential effects on ES provision, we propose a geospatial framework to identify and analyze the cumulative effects on terrestrial and freshwater ES. The framework includs an impact chain analysis based on ten pressures grouped into six categories (pollution, climate change, land-use change, overexploitation, land fragmentation, invasive species) and their single or multiple effects on five key ES of the Alpine environment (recreation, forest protection, CO2 sequestration, habitat maintenance, grassland biomass). Results show that the areas most affected by cumulative effects were located in major urban centers, in the Po Valley, Germany, Slovenia, and in coastal areas of the Adriatic Sea. The spatial coincidence analysis of pressure P-ES on IUCN protected sites showed that protection categories IV and V mostly had high P/high ES scores. Our approach will help in management and planning for mountain conservation aimed at reducing multi-pressure occurrences in transboundary environments. The framework can be used to identify areas with the highest ES provision, characterize areas with high stress from anthropogenic pressures, and examine the effects of pressures on protected areas

Mucinous Carcinoma and IPMN

This book describes the pathways of dissemination of primary liver, biliary, and pancreatic neoplasms and proposes a practical and clinically driven approach to their imaging. The typical dissemination pathways for hepatocellular carcinoma, cholangiocarcinoma, exocrine pancreatic carcinoma, and neuroendocrine pancreatic tumors are systematically reviewed, and more unusual pathways are also documented. The content is presented in an extremely schematic way, with numerous high-quality graphical illustrations and multimodality images (US, CT, MRI, and PET) that are accompanied by clear explanatory text. The clinical significance of findings and potential therapeutic options are explained whenever appropriate. In addition, relevant background information is provided on the role of morphopathological drivers of cancer spread and anatomy