1,100 research outputs found

    Closing Remarks: Where Do We Go From Here

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    Hispanic Subgroups, Acculturation, and Substance Abuse Treatment Outcomes

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    This study explored Hispanic subgroup differences in substance use treatment outcomes, and the relationship of acculturation characteristics to these outcomes. Data were from a multisite randomized clinical trial of motivational enhancement therapy versus treatment as usual in a sample of Spanish-speaking substance abusers. Participants were Cuban American (n = 34), Mexican American (n = 209), Puerto Rican (n = 78), and other Hispanic American (n = 54). Results suggested that Cuban Americans and individuals with more connection to Hispanic culture had lower treatment retention. Hispanics born in the U.S and those who spoke English at home had a lower percentage of days abstinent during weeks 5–16, although Puerto Ricans born in the U.S. and Cuban Americans living more years in the U.S. had a higher percentage of days abstinent in weeks 1–4 and 5–16, respectively. Results may inform future hypothesis-driven studies in larger Hispanic treatment seeking samples of the relationship between acculturation and treatment outcome

    Emotional reactivity and perseveration: Independent dimensions of trait positive and negative affectivity and differential associations with psychological distress

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    Background: Theoretically, two types of emotional responding could underlie individual differences in trait affect: 1) a disposition reflecting increased probability of experiencing positive or negative emotions (emotional reactivity), and 2) a disposition to experience prolonged emotional reactions once elicited (emotional perseveration). We developed a measure of these dimensions and investigated whether emotional reactivity and perseveration 1) account for unique variance in trait affect, and 2) are differentially associated with symptoms of psychological distress. Method: In Study 1, participants (T1: n = 90; T2: n = 51) completed the Positive and Negative Affect Schedule (PANAS) and the Emotional Reactivity and Perseveration Scale (ERPS, adapted from the PANAS). In study 2, participants (n = 228) completed the PANAS, ERPS, and Depression Anxiety Stress Scales. Results: Study 1 established the basic psychometric properties of the ERPS and demonstrated that emotional reactivity and perseveration accounted for unique variance in trait positive and negative effect. Study 2 confirmed these findings and established that emotional reactivity and perseveration are differentially associated with depression, anxiety, and stress scores. Conclusion: Emotional reactivity and perseveration represent independent dimensions of trait affect. Considering these dimension in future research could further the understanding of both normal emotional responding and emotional vulnerability

    Contingent infrastructure and the dilution of ‘Chineseness’: Reframing roads and rail in Kampala and Addis Ababa

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    Amid growing interest in China’s role in financing and building infrastructure in Africa, there is still little research on how Chinese-financed infrastructures are negotiated and realised at the city and metropolitan scale. We compare the Light Rail Transit in Addis Ababa, Ethiopia with the expressway linking Kampala to Entebbe airport in Uganda, examining the processes of bargaining behind these transport infrastructures and their emergent effects on urban land use and city-dwellers’ mobility. We find that both projects were designed and implemented through opaque negotiations between African national elites and Chinese agencies, with little or no engagement from city authorities, leading to haphazard outcomes that are poorly integrated with broader planning. Yet we also suggest that despite being enabled and mediated by Chinese agencies, such projects do not embody a Chinese global vision. They instead reflect the entrepreneurial activities of Chinese contractors and the varying ways in which these connect with African national governments’ shifting priorities. Moreover, as they are subsumed into the urban context, these transposed infrastructures have been rapidly repurposed and their ‘Chineseness’ diluted, with one morphing into an infrastructure for the poor and the other into a site of private value extraction. We thus argue that, far from representing a domineering or neo-colonial influence, Chinese-financed infrastructures that land in institutionally complex African city-regions can be rapidly swallowed up into the political-economic landscape, producing contingent benefits and disbenefits that are far removed from the visions of any planners – Chinese or African, past or present

    Enzymatically Assisted CO<sub>2</sub> Removal from Flue-Gas

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    AbstractThe enzyme carbonic anhydrase is an enzyme known to enhance CO2 absorption rates. However, for economic viability in enzyme based absorption technology long term stability under process relevant conditions is needed. Thus, here enzyme stability for extended times are investigated with respect to pH, temperature and solvent. Temperatures and pH stability were tested for up to 100hours incubation and the enzyme was temperature stable up to 60°C and in the pH range from 7 to 11, with some residual activity between pH 5 and 12. Furthermore, enzyme stability was tested for 7 different capture solvents for 150 days, at 1M or 3M solvent concentrations, 40°C and pH between 8-9 and 10. Residual activity was found with all samples ranging from 12 to 91% of the initial activity. This study show that this enzyme can indeed be used for extended periods in process relevant conditions, and thus shows promise for industrial implementation as a catalyst in carbon capture

    The Thermal Structure of Gas in Pre-Stellar Cores: A Case Study of Barnard 68

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    We present a direct comparison of a chemical/physical model to multitransitional observations of C18O and 13CO towards the Barnard 68 pre-stellar core. These observations provide a sensitive test for models of low UV field photodissociation regions and offer the best constraint on the gas temperature of a pre-stellar core. We find that the gas temperature of this object is surprisingly low (~7-8 K), and significantly below the dust temperature, in the outer layers (Av < 5 mag) that are traced by C18O and 13CO emission. As shown previously, the inner layers (Av > 5 mag) exhibit significant freeze-out of CO onto grain surfaces. Because the dust and gas are not fully coupled, depletion of key coolants in the densest layers raises the core (gas) temperature, but only by ~1 K. The gas temperature in layers not traced by C18O and 13CO emission can be probed by NH3 emission, with a previously estimated temperature of ~10-11 K. To reach these temperatures in the inner core requires an order of magnitude reduction in the gas to dust coupling rate. This potentially argues for a lack of small grains in the densest gas, presumably due to grain coagulation.Comment: 33 pages, 11 figures, accepted by Astrophysical Journa

    The Effect of Attractiveness on Food Sharing Preferences in Human Mating Markets

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    The current study explored how physical attractiveness affects food sharing by studying payment preferences for hypothetical romantic dinner dates (a hypothetical mating market). We analyzed payment preferences, self-rated attractiveness, and rated attractiveness for hypothetical dates in 416 participants. We hypothesized that (1) men would be more likely to prefer to pay than would women, (2) attractive individuals of both sexes would be less willing to pay, and (3) preferences to enter an exchange would be influenced by the attractiveness of prospective partners such that (3a) men would prefer to pay for attractive women, and (3b) women would prefer to be paid for by attractive men. All hypotheses were supported by our results. Individuals with higher self-rated attractiveness were more likely to prefer that their date would pay for the meal, and we found clear sex differences in how the attractiveness of potential dates affected payment preferences. Male participants preferred to pay for dates that had higher facial attractiveness, while female participants preferred that attractive men would pay. Individuals show condition dependent financial preferences consistent with the provisioning hypothesis in this mating market that are adaptive to evaluations of their own quality and that of prospective partners

    The rebound effect on water extraction from subsidising irrigation infrastructure in Australia

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    Over the past decade, Australia has been buying water entitlements and subsidising irrigation infrastructure to reallocate water from consumptive to environmental purposes in the Murray-Darling Basin (MDB). There is considerable evidence that irrigation infrastructure subsidies are not cost-effective, as well as questions as to whether water extractions are increasing (rebounding) as a result. We used 2481 on-farm MDB irrigation surveys and identified a ‘rebound effect’ on water extractions, with irrigators who received an irrigation infrastructure subsidy significantly increasing (21-28%) their water extraction, relative to those who did not receive any grants. Although the precise hydrological impact of this rebound effect on catchment and Basin-wide extractions remains unknown, publicly available water data suggest that reductions in extractions from the MDB – supposedly commensurate with increases in environmental flows – may have been overestimated, particularly in the Northern MDB. This overestimation may in turn be linked to issues with water measurement and extractions at the catchment and Basin-scale, which occur due to: (1) water theft and poor enforcement; (2) inaccurate or absent water metering; (3) growth in unlicensed surface and groundwater extractions and on-farm storage capacity; (4) legal and practical uncertainties in compliance tools, processes and water accounting; and (5) complexity of floodplain, evaporation and groundwater interactions. To respond to these water governance challenges, MDB water and rural policy actions must: (1) improve measurement of diversions and develop transparent and robust water accounting, independently audited and accounting for uncertainty; (2) improve compliance, fines and regulation; (3) use multiple lines of evidence for water accounting and compliance; and (4) prioritise the cost and environmental effectiveness of water recovery

    Extreme magnesium isotope fractionation at outcrop scale records the mechanism and rate at which reaction fronts advance

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    Isotopic fractionation of cationic species during diffusive transport provides novel means of constraining the style and timing of metamorphic transformations. Here we document a major (~1‰) decrease in the Mg isotopic composition of the reaction front of an exhumed contact between rocks of subducted crust and serpentinite, in the Syros mélange zone. This isotopic perturbation extends over a notable length-scale (~1 m), implicating diffusion of Mg through an intergranular fluid network over a period of ~100 kyr. These novel observations confirm models of diffusion-controlled growth of reaction zones formed between rocks of contrasting compositions, such as found at the slab-mantle interface in subduction zones. The results also demonstrate that diffusive processes can result in exotic stable isotope compositions of major elements with implications for mantle xenoliths and complex intrusions

    The IĸB protein BCL3 controls osteogenesis and bone health.

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    OBJECTIVE: IĸB protein B-cell lymphoma 3-encoded protein (BCL3) is a regulator of the NF-κB family of transcription factors. NF-κB signalling fundamentally influences the fate of bone-forming osteoblasts and bone-resorbing osteoclasts, but the role of BCL3 in bone biology has not been investigated. The objective of this study was to evaluate BCL3 in skeletal development, maintenance and osteoarthritic pathology. METHODS: To assess the contribution of BCL3 to skeletal homeostasis, neonatal mice (n = 6-14) lacking BCL3 (Bcl3-/- ) and WT controls were characterised for bone phenotype and density. To reveal the contribution to bone phenotype by the osteoblast compartment in Bcl3-/- mice, transcriptomic analysis of early osteogenic differentiation and cellular function (n = 3-7) were assessed. Osteoclast differentiation and function in Bcl3-/- mice (n = 3-5) was assessed. Adult 20-week Bcl3-/- and WT mice bone phenotype, strength and turnover were assessed. A destabilisation of the medial meniscus (DMM) model of osteoarthritic ostephytogenesis was utilised to understand adult bone formation in Bcl3-/- mice (n = 11-13). RESULTS: Evaluation of Bcl3-/- mice revealed congenitally increased bone density, long bone dwarfism, increased bone biomechanical strength and altered bone turnover. Molecular and cellular characterisation of mesenchymal precursors showed that Bcl3-/- cells display an accelerated osteogenic transcriptional profile that leads to enhanced differentiation into osteoblasts with increased functional activity; which could be reversed with a mimetic peptide. In a model of osteoarthritis-induced osteophytogenesis, Bcl3-/- mice exhibit decreased pathological osteophyte formation (P < 0.05). CONCLUSION: Cumulatively, these findings demonstrate that BCL3 controls developmental mineralisation to enable appropriate bone formation, whilst in a pathological setting it contributes to skeletal pathology
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