Foraminifera of shallow and very shallow facies from the upper Eocene-lower Oligocene Kazandere Member, Soğucak Formation, Thrace Basin, northwest Turkey

The middle-late Eocene to early Oligocene sediments, mainly limestone of the Soğucak Formation with its shallow water marine foraminiferal species occur most widespread in the territory of the Thrace basin. So far, the very shallow water Priabonian sediments with here described foraminiferal species have not been reported from Tharece basin. The here established Kazandere memeber of the Soğurcak Formation located between Kıyıköy andKömürköy,(NW of Kırklarel) was studied with respect to the sedimentologic as (microscopic and macroscopic), environmental and descriptive paleontology of the bentic foraminifers. Furthermore, the Eocene-Oligocene boundary in the new member defined first by the here described very shallow-water Priabonian and known shallow-water early Oligocene foraminiferal species

Foraminifera of shallow and very shallow facies from the upper Eocene–lower Oligocene Kazandere Member, Soğucak Formation, Thrace Basin, northwest Turkey

The middle−upper Eocene to lower Oligocene Kazandere Limestone Member of the Soğucak Formation is widely represented in the Thrace Basin and rich in shallow-water marine foraminifera. Very shallow-water Priabonian facies described here include Borelis vonderschimitti, Borelis laxispira sp. nov., Chapmanina gassinensis, Chapmanina elongate sp. nov., Pfendericonusglobulus sp. nov., Orbitolites minimus,Coscinospira sp. Last occurrences of the aforementioned Priabonian species and first appearances of the shallow-water marine Rupelian species Nummulites fichteli, Nummulites vascus and Operculina complanata define the Eocene−Oligocene boundary in the new Kazandere Member at the northeast Thrace Basin

Congenital Diarrhea and Cholestatic Liver Disease: Phenotypic Spectrum Associated with MYO5B Mutations.

Myosin Vb (MYO5B) is a motor protein that facilitates protein trafficking and recycling in polarized cells by RAB11- and RAB8-dependent mechanisms. Biallelic MYO5B mutations are identified in the majority of patients with microvillus inclusion disease (MVID). MVID is an intractable diarrhea of infantile onset with characteristic histopathologic findings that requires life-long parenteral nutrition or intestinal transplantation. A large number of such patients eventually develop cholestatic liver disease. Bi-allelic MYO5B mutations are also identified in a subset of patients with predominant early-onset cholestatic liver disease. We present here the compilation of 114 patients with disease-causing MYO5B genotypes, including 44 novel patients as well as 35 novel MYO5B mutations, and an analysis of MYO5B mutations with regard to functional consequences. Our data support the concept that (1) a complete lack of MYO5B protein or early MYO5B truncation causes predominant intestinal disease (MYO5B-MVID), (2) the expression of full-length mutant MYO5B proteins with residual function causes predominant cholestatic liver disease (MYO5B-PFIC), and (3) the expression of mutant MYO5B proteins without residual function causes both intestinal and hepatic disease (MYO5B-MIXED). Genotype-phenotype data are deposited in the existing open MYO5B database in order to improve disease diagnosis, prognosis, and genetic counseling

Penil septal hematom: Nadir bir olgu sunumu

Hematoma associated with penile trauma, usually associated with a penile fracture involving a disruption in the integrity of tunica albuginea, is among the frequent causes of a penile mass. In this report, the authors present a 70-year-old patient with intercorporeal penile septal hematoma without a rupture of tunica albuginea following a traumatic event. Relevant imaging features are conclusive for an accurate diagnosis, particularly in cases with atypical clinical presentation, as was in the presented case.Penil travmaya bağlı olarak gelişen ve çoğu kez tunika albuginea’nın bütünlüğünde bir bozulmanın ve hematom oluşumunun eşlik ettiği klinik tablo en sık görülen penil kitle nedenidir. Bu yazıda, travma sonucu gelişen ve tunika albuginea’da bir rüptürün sözkonusu olmadığı 70 yaşındaki bir interkorporeal penil septal hematom olgusu sunulmaktadır. Sunulan olguda olduğu gibi, özellikle atipik bir kliniğin sözkonusu olduğu olgularda doğru tanı konulabilmesi için görüntüleme bulguları önem taşımaktadır

Penil septal hematom: Nadir bir olgu sunumu

Hematoma associated with penile trauma, usually associated with a penile fracture involving a disruption in the integrity of tunica albuginea, is among the frequent causes of a penile mass. In this report, the authors present a 70-year-old patient with intercorporeal penile septal hematoma without a rupture of tunica albuginea following a traumatic event. Relevant imaging features are conclusive for an accurate diagnosis, particularly in cases with atypical clinical presentation, as was in the presented case.Penil travmaya bağlı olarak gelişen ve çoğu kez tunika albuginea’nın bütünlüğünde bir bozulmanın ve hematom oluşumunun eşlik ettiği klinik tablo en sık görülen penil kitle nedenidir. Bu yazıda, travma sonucu gelişen ve tunika albuginea’da bir rüptürün sözkonusu olmadığı 70 yaşındaki bir interkorporeal penil septal hematom olgusu sunulmaktadır. Sunulan olguda olduğu gibi, özellikle atipik bir kliniğin sözkonusu olduğu olgularda doğru tanı konulabilmesi için görüntüleme bulguları önem taşımaktadır

SPATIAL DISTRUBITON OF CHILDREN TREATED BY CANCER IN ZONGULDAK, TURKEY

This research is focused on the examination of child cancer cases in Zonguldak (Turkey) descriptively in epidemiological aspect thanks to GIS. Universe of the study is composed of 60 children between 0-19 years old, treated in Children Oncology Clinic of Health Application and Research Center in BEU. Whole universe was reached without selecting a sample in the study. Data were collected by using a form prepared by obtaining expert advice and they were applied to children and their parents at study dates. Results were expressed as percentages. Chi-Square test was used in intergroup comparisons, results were assessed within 95% confidence interval and p<0.05 was considered as statistically significant. Variables that were used in the study were assessed, recorded in prepared data collection form and distribution maps were produced. When disease diagnosis of the children participated in the study were evaluated, it was observed that 33.3% (n=20) were being treated for ALL, 13.3% (n=8) for Medullablastoma and 11.7% (n=7) for Hodgkin-nonHodgkin Lymphoma. It was detected that 31.7% (n=19) were in Ereğli, 31.7% (n=19) were in Central district and 18.3% (n=11) were in Çaycuma, when the places where children were living were evaluated. Statistically significant difference was found (p=0.016) comparing disease diagnosis with living place, and overall distribution map of the number of cancer cases was produced in this context. This is the first research subjecting the distribution of cancer cases for Zonguldak province

Application of multivariate chemometric techniques for simultaneous determination of five parameters of cottonseed oil by single bounce attenuated total reflectance Fourier transform infrared spectroscopy

WOS:000341463400065PubMed:25127621Single bounce attenuated total reflectance (SB-ATR) Fourier transform infrared (FTIR) spectroscopy in conjunction with chemometrics was used for accurate determination of free fatty acid (FFA), peroxide value (PV), iodine value (IV), conjugated diene (CD) and conjugated triene (CT) of cottonseed oil (CSO) during potato chips frying. Partial least square (PLS), stepwise multiple linear regression (SMLR), principal component regression (PCR) and simple Beer's law (SBL) were applied to develop the calibrations for simultaneous evaluation of five stated parameters of cottonseed oil (CSO) during frying of French frozen potato chips at 170 degrees C. Good regression coefficients (R-2) were achieved for FFA, PV, IV, CD and CT with value of > 0.992 by PLS, SMLR, PCR, and SBL. Root mean square error of prediction (RMSEP) was found to be less than 1.95% for all determinations. Result of the study indicated that SB-ATR FTIR in combination with multivariate chemometrics could be used for accurate and simultaneous determination of different parameters during the frying process without using any toxic organic solvent. (C) 2014 Elsevier B.V. All rights reserved.Scientific and Technological Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK)The authors would like to thank the Scientific and Technological Research Council of Turkey (TUBITAK) under the 2216 Research Fellowship Program for Foreign Citizens for providing the financial support to carry out this research work and also thanks of Analytical Chemistry Department at Selcuk University, Konya Turkey for providing a good environment for research work