Second Backbend in the Mass A ~ 180 Region

Within the framework of selfconsistent cranked Hartree-Fock- Bogoliubov theory(one-dimensional) we predict second backbend in the yrast line of Os-182 at $I \approx 40$, which is even sharper than the first one observed experimentally at $I \approx 14$. Around such a high spin the structure becomes multi-quasiparticle type, but the main source of this strong discontinuity is a sudden large alignment of i_13/2 proton orbitals along the rotation axis followed soon by the alignment of j_15/2 neutron orbitals. This leads to drastic structural changes at such high spins. When experimentally confirmed, this will be observed for the first time in this mass region, and will be at the highest spin so far.Comment: 13 pages, 4 ps figure

Compared to What? Is BMI Associated with Histopathological Changes in Laparoscopic Sleeve Gastrectomy Specimens?

Background: Obesity is a risk for many different cancers. Laparoscopic sleeve gastrectomy (LSG) is common, and benign or pre-malignant histopathology types are reported in the removed gastric specimens. We assessed whether higher BMI was associated with certain benign or pre-malignant histopathological changes. Method: Retrospective chart review of all primary LSG patients (N = 1555). Demographic, clinical, and LSG histopathology data were retrieved. BMI of patients with specific benign or pre-malignant conditions in their gastric specimens was compared with the BMI of the rest of the patients with abnormal histopathology specimens and also compared with the BMI of patients with normal control specimens. Results: Females comprised 70% of the patients. Mean BMI were 46.3 (females) and 48 (males). Normal LSG specimens comprised 52%. Most common abnormal histopathologies were chronic inactive gastritis (33%), chronic active gastritis (6.8%), follicular gastritis (2.7%), lymphoid aggregates (2.2%), intestinal metaplasia (1.4%) and GIST (0.7%). After controlling for confounders (age, gender, H. pylori, diabetes mellitus type 2, hypertension), no significant association was observed between the BMI of patients with specific benign or pre-malignant histopathology compared with the BMI of the rest of the patients with abnormal histopathologies and compared to the BMI of patients with normal histopathologies. Conclusion: When confounders were taken into account, there appeared no significant associations between the BMI of patients with specific benign or pre-malignant histopathology compared with the BMI of the rest of the patients with abnormal histopathologies and compared to the BMI of patients with normal histopathologies of their gastric specimens. There was a very weak correlation between BMI and other covariates. - 2019, The Author(s).Acknowledgements Open Access funding provided by the Qatar National Library. The authors wish to thank Dr. Prem Chandra for assistance with the statistical analysis and the Medical Research Center at HMC for their support for the current study.Scopu

Large Magellanic Cloud Microlensing Optical Depth with Imperfect Event Selection

I present a new analysis of the MACHO Project 5.7 year Large Magellanic Cloud (LMC) microlensing data set that incorporates the effects of contamination of the microlensing event sample by variable stars. Photometric monitoring of MACHO LMC microlensing event candidates by the EROS and OGLE groups has revealed that one of these events is likely to be a variable star, while additional data has confirmed that many of the other events are very likely to be microlensing. This additional data on the nature of the MACHO microlensing candidates is incorporated into a simple likelihood analysis to derive a probability distribution for the number of MACHO microlens candidates that are true microlensing events. This analysis shows that 10-12 of the 13 events that passed the MACHO selection criteria are likely to be microlensing events, with the other 1-3 being variable stars. This likelihood analysis is also used to show that the main conclusions of the MACHO LMC analysis are unchanged by the variable star contamination. The microlensing optical depth toward the LMC is = 1.0 +/- 0.3 * 10^{-7}. If this is due to microlensing by known stellar populations, plus an additional population of lens objects in the Galactic halo, then the new halo population would account for 16% of the mass of a standard Galactic halo. The MACHO detection exceeds the expected background of 2 events expected from ordinary stars in standard models of the Milky Way and LMC at the 99.98% confidence level. The background prediction is increased to 3 events if maximal disk models are assumed for both the MilkyWay and LMC, but this model fails to account for the full signal seen by MACHO at the 99.8% confidence level.Comment: 20 pages, 2 postscript figues, accepted by Ap

Heterogeneity of autoreactive T cell clones specific for the E2 component of the pyruvate dehydrogenase complex in primary biliary cirrhosis.

The extraordinary specificity of bile duct destruction in primary biliary cirrhosis (PBC) and the presence of T cell infiltrates in the portal tracts have suggested that biliary epithelial cells are the targets of an autoimmune response. The immunodominant antimitochondrial response in patients with PBC is directed against the E2 component of pyruvate dehydrogenase (PDC-E2). Hitherto, there have only been limited reports on the characterization and V beta usage of PDC-E2-specific cloned T cell lines. In this study, we examined peripheral blood mononuclear cells (PBMC) for their reactivity to the entire PDC complex as well as to the E1- and E2-specific components. We also examined the phenotype, lymphokine profile, and V beta usage of PDC-specific T cell clones isolated from cellular infiltrates from the livers of PBC patients. We report that PBMC from 16/19 patients with PBC, but not 12 control patients, respond to the PDC-E2 subunit. Interestingly, this response was directed to the inner and/or the outer lipoyl domains, despite the serologic observation that the autoantibody response is directed predominantly to the inner lipoyl domain. Additionally, lymphokine analysis of interleukin (IL) 2/IL-4/interferon gamma production from individual liver-derived autoantigen-specific T cell clones suggests that both T helper cell Th1- and Th2-like clones are present in the liver. Moreover, there was considerable heterogeneity in the T cell receptor for antigen (TCR) V beta usage of these antigen-specific autoreactive T cell clones. This is in contrast to murine studies in which animals are induced to develop autoimmunity by specific immunization and have an extremely limited T cell V beta repertoire. Thus, our data suggest that in human organ-specific autoimmune diseases, such as PBC, the TCR V beta repertoire is heterogenous

A contact-based social network of lizards is defined by low genetic relatedness among strongly connected individuals

Author version made available in accordance with the Publisher's policy, after an embargo period of 24 months from the date of publication. © 2015. Licensed under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/Social organization is widespread; even largely solitary species must organize themselves to enable contacts with mates and reduce competition with conspecifics. Although the forms of social structure can be subtle in solitary species, understanding the factors that influence them may be important for understanding how different forms of social organization evolved. We investigated the influence of genetic relatedness and spatial structure on social associations in a solitary living Australian scincid lizard, Tiliqua rugosa. We derived the genetic relatedness of 46 lizards from analysis of genotypes at 15 microsatellite DNA loci, and described social networks from GPS locations of all the lizards every 10 min for 81 days during their main activity period of the year. We found that connected male dyads were significantly more related than expected by chance, whereas connected male–female and female–female dyads had lower relatedness than expected. Among neighbouring male–male and male–female dyads, the strongest social relationships were between lizards that were the least related. Explanations of this pattern may include the avoidance of inbreeding in male–female dyads, or the direction of aggressive behaviour towards less related individuals in male–male dyads. Observed social associations (inferred through synchronous spatial proximity) were generally lower than expected from null models derived from home range overlap, and many close neighbours did not make social contact. This supports our hypothesis for the presence of deliberate avoidance between some neighbouring individuals. We suggest that lizards can discriminate between different levels of relatedness in their neighbours, directing their social interactions towards those that are less related. This highlights differences in how social associations are formed between species that are solitary (where associations form between unrelated conspecifics) and species that maintain stable social groups structured by kinship.Our sleepy lizard research was funded by the Australian Research Council

Biodiesel production from Cannabis sativa oil from Pakistan

The present study was appraised using response surface methodology for process optimization owing to strong interaction of reaction variables: NaOCH3 catalyst concentration (0.25–1.50%), methanol/oil molar ratio (3:1–9:1), reaction time (30–90 min), and reaction temperature (45–65°C). The quadratic polynomial equation was determined using response surface methodology for predicting optimum methyl esters yield from Cannabis sativa oil. The analysis of variance results indicated that molar ratio and reaction temperature were the key factors that appreciably influence the yield of Cannabis sativa oil methyl esters. The significant (p < 0.0001) variable interaction between molar ratio × catalyst concentration and reaction time × molar ratio was observed, which mostly affect the Cannabis sativa oil methyl esters yield. The optimum Cannabis sativa oil methyl esters yield, i.e., 86.01% was gained at 53°C reaction temperature, 7.5:1 methanol/oil molar ratio, 65 min reaction time, and 0.80% catalyst concentration. The results depicted a linear relationship between observed and predicted values. The residual analysis predicted the appropriateness of the central composite design. The Cannabis sativa oil methyl esters, analyzed by gas chromatography, elucidated six fatty acid methyl esters (linoleic, α-linolenic, oleic, palmitic, stearic, and γ-linolenic acids). In addition, the fuel properties, such as kinematic viscosity at 40°C; cetane number; acid value; flash point; cloud, pour, and cold filter plugging points; ash content; density; and sulphur content, of Cannabis sativa oil methyl esters were evaluated and discussed with reference to ASTM D 6751 and EU 14214 biodiesel specifications

Microlensing toward crowded fields: Theory and applications to M31

We present a comprehensive treatment of the pixel-lensing theory and apply it to lensing experiments and their results toward M31. Using distribution functions for the distances, velocities, masses, and luminosities of stars, we derive lensing event rates as a function of the event observables. In contrast to the microlensing regime, in the pixel-lensing regime (crowded or unresolved sources) the observables are the maximum excess flux of the source above a background and the full width at half-maximum (FWHM) time of the event. To calculate lensing event distribution functions depending on these observables for the specific case of M31, we use data from the literature to construct a model of M31, reproducing consistently photometry, kinematics and stellar population. We predict the halo- and self-lensing event rates for bulge and disk stars in M31 and treat events with and without finite source signatures separately. We use the M31 photon noise profile and obtain the event rates as a function of position, field of view, and S/N threshold at maximum magnification. We calculate the expected rates for WeCAPP and for a potential Advanced Camera for Surveys (ACS) lensing campaign. The detection of two events with a peak signal-to-noise ratio larger than 10 and a timescale larger than 1 day in the WeCAPP 2000/2001 data is in good agreement with our theoretical calculations. We investigate the luminosity function of lensed stars for noise characteristics of WeCAPP and ACS. For the pixel-lensing regime, we derive the probability distribution for the lens masses in M31 as a function of the FWHM timescale, flux excess and color, including the errors of these observables.Comment: 45 pages, 27 figures LaTeX; corrected typos; published in the Astrophysical Journal Supplemen

Young Muslim women's experiences of Islam and physical education in Greece and Britain: a comparative study

Previous research suggests that Muslim women can experience particular problems when taking physical education (PE) lessons, for example with dress codes, mixed-teaching and exercise during Ramadan; and they can face restrictions in extra-curricular activities for cultural and religious reasons. The area is under-researched and there is little evidence of comparative studies that explore similarities and differences in cross-national experiences, which is the aim of this paper. Two studies conducted in Greece and Britain that explored the views of Muslim women on school experiences of physical education are compared. Both studies focused on diaspora communities, Greek Turkish girls and British Asian women, living in predominantly non-Muslim countries. Growing concerns about global divisions between 'Muslims and the West' make this a particularly pertinent study. Qualitative data were collected by interviews with 24 Greek Muslim women, and 20 British Muslim women. \ud <P> \ud Physical education has national curriculum status and a similar rationale in both countries but with different cultures of formality and tradition, which impacted on pupils' experiences. Data suggested that Greek and British groups held positive views towards physical education but were restricted on their participation in extra-curricular activities. For the British women religious identity and consciousness of Islamic requirements were more evident than for the Greek women. Differences in stages of acculturation, historical and socio-cultural contexts contributed to less problematic encounters with physical education for Greek Muslims who appeared more closely assimilated into the dominant culture