Improving Content Area Reading in a Middle School Core Classroom

Many middle school students cannot adequately use content area textbooks. This project begins with a review of the research literature related to this concern. The literature review is followed by a content area reading program designed for an eighth grade core classroom. The program is composed of sequential directions and worksheets to teach diverse content area reading techniques. The relative values of different techniques are discussed, and suggestions for future studies are offered

La migration au risque de l'illégalité entre France et Algérie (1998-2004)

Mis en ligne le 01 décembre 2011, consulté le 10 septembre 2012. URL : http://remi.revues.org/483

A PCA3 gene-based transcriptional amplification system targeting primary prostate cancer.

Targeting specifically primary prostate cancer (PCa) cells for immune therapy, gene therapy or molecular imaging is of high importance. The PCA3 long non-coding RNA is a unique PCa biomarker and oncogene that has been widely studied. This gene has been mainly exploited as an accurate diagnostic urine biomarker for PCa detection. In this study, the PCA3 promoter was introduced into a new transcriptional amplification system named the 3-Step Transcriptional Amplification System (PCA3-3STA) and cloned into type 5 adenovirus. PCA3-3STA activity was highly specific for PCa cells, ranging between 98.7- and 108.0-fold higher than that for benign primary prostate epithelial or non-PCa cells, respectively. In human PCa xenografts, PCA3-3STA displayed robust bioluminescent signals at levels that are sufficient to translate to positron emission tomography (PET)-based reporter imaging. Remarkably, when freshly isolated benign or cancerous prostate biopsies were infected with PCA3-3STA, the optical signal produced from primary PCa biopsies was significantly higher than from benign prostate biopsies (4.4-fold, p < 0.0001). PCA3-3STA therefore represents a PCa-specific expression system with the potential to target, with high accuracy, primary or metastatic PCa epithelial cells for imaging, vaccines, or gene therapy

A Standalone FPGA-based Miner for Lyra2REv2 Cryptocurrencies

Lyra2REv2 is a hashing algorithm that consists of a chain of individual hashing algorithms, and it is used as a proof-of-work function in several cryptocurrencies. The most crucial and exotic hashing algorithm in the Lyra2REv2 chain is a specific instance of the general Lyra2 algorithm. This work presents the first hardware implementation of the specific instance of Lyra2 that is used in Lyra2REv2. Several properties of the aforementioned algorithm are exploited in order to optimize the design. In addition, an FPGA-based hardware implementation of a standalone miner for Lyra2REv2 on a Xilinx Multi-Processor System on Chip is presented. The proposed Lyra2REv2 miner is shown to be significantly more energy efficient than both a GPU and a commercially available FPGA-based miner. Finally, we also explain how the simplified Lyra2 and Lyra2REv2 architectures can be modified with minimal effort to also support the recent Lyra2REv3 chained hashing algorithm.Comment: 13 pages, accepted for publication in IEEE Trans. Circuits Syst. I. arXiv admin note: substantial text overlap with arXiv:1807.0576

Russian air patrols in the Arctic : are long-range bomber patrols a challenge to canadian security and sovereignty?

Western, and especially Canadian media reported, especially during the period 2007-2011, a significant number of Russian air patrols in the Arctic. These patrols were often described as potential threats for the Canadian security and sovereignty. However, a comparative analysis of the frequency of Russian air patrols in the Arctic and in other areas of operation attest to the rather low level of activity of the Russian air force. This suggests the narrative about the would-be Russian air threat reflects either misinformation or an oriented political discourse