Phytochemistry and Pharmacological review: Nigella sativa

Habba-tul-barka or Black cumin seeds (Nigella sativa) belongs to the family Ranunculaceae. It is an important seeds due to its nutritional and medicinal properties. N. sativa is widely distributed worldwide and, therefore, has a broad genetic diversity, resulting in differences in their phytochemical composition. The scientific community has focused on the positive health effects of N. sativa as a whole, but the different varieties have rarely been compared according to their bioactive compounds and bioactivity. This review aims to provide a holistic overview of the current knowledge on the bioactivity of N. sativa. This review intends to provide a general and organized overview of the accumulated knowledge on N. sativa, identify the most bioactive varieties, their potential consumption pathways, and provide knowledge on the present gaps to guide future research

Role of labour admission test in predicting pregnancy outcome in low-risk cases

Background: The present study was carried out to determine the role of labour admission test (LAT) in detecting fetal hypoxia in labour and to correlate the findings of the test with perinatal outcome in low-risk cases.Methods: In this study 150 low risk pregnant term women were subjected to LAT and classified according to NICE 2017 guidelines. Pregnancy outcome in terms of need for operative delivery and neonatal status at birth were noted. Data was analysed statistically by Chi-square test.Results: The LAT was normal in 78.67%, suspicious in 17.33% and pathological in 4%. Operative delivery for fetal distress was observed in 18.75% of normal group, in 50% of suspicious group and in 100% of pathological group. The incidence of meconium-stained liquor was significantly high in pathological (50%) and suspicious group (19.23%). The incidence of low 5-minute Apgar score was significantly high in pathological LAT group (33.33%) as compared to suspicious (7.69%) and normal LAT groups (2.54%). Admission to neonatal intensive care unit (NICU) was significantly high in pathological test group (50%). LAT in this study showed 48.15% sensitivity, 96.75% specificity and 76.47% positive predictive value as a screening tool for predicting fetal distress in low-risk patients suggesting that a normal LAT in early labour is an indicator of good pregnancy outcome.Conclusions: LAT is an effective, non-invasive screening method with good specificity to detect fetal distress in low-risk woman and helps to plan management accordingly to improve pregnancy outcome

Nurse teachers’ conceptions and practices of written feedback in Karachi.

Background: Written Feedback (WFB) plays a significant role in student’s learning in terms of improvement of their academic writing skills. However, the quality of WFB may be affected by various personal and contextual factors. This study aimed to identify nurse teachers’ conceptions and practices of WFB on written assignments in nursing degree offering institutions in Karachi, Pakistan. Methods: A cross-sectional descriptive study design was used to answer the study questions. The study was conducted at 11 nursing schools in Karachi by recruiting those teachers who were teaching in nursing degree programs. The sample size of the study consists of 80 teachers. Universal sampling technique was used to select the subjects of the study. Results: The study result consists of demographic information of the participants, teachers’ conceptions and their practices of WFB. Although majority (92%) of the teachers believed that WFB is important for students’ learning, they acknowledged that they were not able to provide WFB at optimum level to their students. This gap in practice is attributed to various personal, contextual, and organizational factors; among them, the highest reported factors were teachers’ lack of training for provision of WFB (84%), distraction in the environment (78%), and constraints of time due to teacher’s workload (74%). Conclusions: The importance of WFB for students’ learning is well established in the literature. However, the preparation of teachers and an enabling environment to facilitate teachers for optimum practices of WFB needs considerable attention by educational institutions

Gender Roles in Pakistani-urdu Wedding Songs

This qualitative study of Pakistani-Urduwedding songs allows a closer look at the gender situation,and towards the understanding of the process ofconstruction and perpetuation of gender-basedstereotypes. However, the major concern of this study is tounderstand the portrayal of each gender along with thequestion that does such portrayal underlines thetraditional gender roles and gender inequality. Taking adiscourse analysis perspective, this study analyzes textualdata from the lyrics of the seventeen wedding songs. Thesong selection was based on purposive samplingtechnique. The data were collected through transcriptionand recording of the audios of the songs. As a result ofthematic analysis thirteen themes emerged, ten portrayingthe female gender and four portraying the male gender.These themes reveal important findings that support andreinforce the gender-based stereotypes and also reflectgender hierarchy, normative heterosexual relationships,kinship norms and gender subversions

Socio-demographic profile of poisoning in children admitted to a tertiary hospital

Background: Childhood poisoning is a significant public health problem and is very important cause of mortality and morbidityin children. The offending substances used vary from place to place. The pattern of poisoning has been changing with new hazardsconstantly appearing due to the introduction of new drugs and chemicals. Childhood poisoning is usually accidental makingpoisoning a preventable problem. Objectives: To determine the socio-demographic and clinical profile and outcome of childhoodpoisoning in a tertiary care hospital. Materials and Methods: This prospective study was done over a period of 2-year in a tertiarycare hospital. We studied children <15 years of age who were admitted to our hospital with a history of poisoning. Children withhistory of food poisoning, snake bite, scorpion sting, and insect bites were excluded from the study. The demographic profile ofpatients, various substances of poisoning, mode of poisoning, and outcome of admitted children with poisoning were studied.Results: Among 200 children admitted with the history of poisoning, 126 (63%) were boys and 74 (37%) were girls. The majorityof the poisoning were accidental in nature and found to be common in the age group of 1-5 years, children from rural areas, and areof lower socio-economic status. Kerosene poisoning was the most common (35%) agent followed by organophosphorus poisoning(11%). 4 children died due to various complications of poisoning. Conclusion: Common household products were found to be themain source of poisoning in younger age groups from rural background, and the majority was accidental in nature. Educationalprograms toward creating awareness among public are necessary to reduce the incidence of poisoning in children

Social Problems are Social: Empirical Evidence and Reflections on Integrating Community Psychology into Traditional Curriculum

The paper will describe the development and impact of a course that exemplifies the principles and values of community psychology, but does so outside the bounds of a community psychology program or concentration in a large, diverse, public university. The class, Community Engagement for Social Change, has two aims: to teach undergraduates that social problems have social causes, and to engage students in a range of social problem-solving approaches that incorporate that understanding. It accomplishes these aims by introducing a “multi-level analysis” of social problems, using a case study of the social problem of poverty, and requiring that all students complete 20 hours of service in community organizations. The development of the class required strategic thinking and significant retooling in order to attract and promote learning across a broad range of students. It has now been offered each semester for seven years, and has evolved into an opportunity for the first author and her graduate students to integrate social justice-oriented teaching and research. For the past three years, the authors have been engaged in a longitudinal project evaluating the impact of the class on student outcomes. This paper provides an overview of this course, and describes lessons learned from two sources: (1) the experience of teaching and refining the class, and (2) the longitudinal dataset collected from students who did and did not take the course. Data show that the class is effective in shifting attitudes both specific to poverty and more generally to social problems. Results also show that implicit bias did not shift over the course of the semester, and that individual and systemic attributions for social problems are only moderately related. We hope that sharing our experience is useful to those interested in similar coursework in other institutions that lack an explicit focus on community psychology

Social Problems are Social: Empirical Evidence and Reflections on Integrating Community Psychology into Traditional Curriculum

The paper will describe the development and impact of a course that exemplifies the principles and values of community psychology, but does so outside the bounds of a community psychology program or concentration in a large, diverse, public university. The class, Community Engagement for Social Change, has two aims: to teach undergraduates that social problems have social causes, and to engage students in a range of social problem-solving approaches that incorporate that understanding. It accomplishes these aims by introducing a “multi-level analysis” of social problems, using a case study of the social problem of poverty, and requiring that all students complete 20 hours of service in community organizations. The development of the class required strategic thinking and significant retooling in order to attract and promote learning across a broad range of students. It has now been offered each semester for seven years, and has evolved into an opportunity for the first author and her graduate students to integrate social justice-oriented teaching and research. For the past three years, the authors have been engaged in a longitudinal project evaluating the impact of the class on student outcomes. This paper provides an overview of this course, and describes lessons learned from two sources: (1) the experience of teaching and refining the class, and (2) the longitudinal dataset collected from students who did and did not take the course. Data show that the class is effective in shifting attitudes both specific to poverty and more generally to social problems. Results also show that implicit bias did not shift over the course of the semester, and that individual and systemic attributions for social problems are only moderately related. We hope that sharing our experience is useful to those interested in similar coursework in other institutions that lack an explicit focus on community psychology

Natural materials

The use of naturally occurring materials as scaffolds to support cell growth and proliferation significantly impacted the origin and progress of tissue engineering and regenerative medicine. However, the majority of these materials failed to provide adequate cues to guide cell differentiation toward the formation of new tissues. Over the past decade, a new generation of multifunctional and smart natural-based materials has been developed to provide biophysical and biochemical cues intended to specifically guide cell behavior. In this chapter, the use of extracellular matrix proteins and blood-derivatives intrinsic capacity to mimic the biophysical and biological characteristics of native tissues is reviewed. Furthermore, the design of a variety of nanostructures using the well-explored characteristics of nucleic acids is summarized. In the second section, the exploitation of supramolecular chemistry to create new dynamic functional hydrogels that mimic the extracellular matrix structure and/or composition is surveyed. Then, the incorporation of nanoelements in polymeric networks for the design of smart nanocomposite materials with tailored functionalities to guide cell behavior is introduced. Finally, the future perspectives in the development of new biomaterials for tissue engineering and regenerative medicine are presented.Te authors acknowledge the fnancial support of the European Union Framework Programme for Research and Innovation Horizon 2020, under the TEAMING grant agreement No 739572 – Te Discoveries CTR, Marie Skłodowska-Curie grant agreement No 706996 and European Research Council grant agreement No 726178; FCT (Fundação para a Ciência e a Tecnologia) and the Fundo Social Europeu através do Programa Operacional do Capital Humano (FSE/POCH) in the framework of Ph.D. grants PD/BD/113807/2015 (BBM) and PD/BD/129403/2017 (SMB), Post-Doc grant SFRH/ BPD/112459/2015 (RMD) and project SmarTendon (PTDC/NAN-MAT/30595/2017); Project NORTE01-0145-FEDER-000021 supported by Norte Portugal Regional Operational Programme (NORTE 2020), under the PORTUGAL 2020 Partnership Agreement, through the European Regional Development Fund (ERDF

Effect of Surface Roughness on the Squeeze Film Characteristics of Circular Plates in the Presence of Conducting Couplestress Fluid and Transverse Magnetic Field

The combined effect of surface roughness and magnetic field on the performance characteristic of the circular plates lubricated with conducting couplestress fluid (CCSF) has been studied. On the basis of the Christensen Stochastic model, the generalized stochastic Reynold’s equation is derived. Modified equations for the nondimensional pressure, load load-carrying capacity, and squeeze film time are derived. The results are presented both numerically and graphically and compared with conducting smooth surface case. It is observed that the surface roughness effects are more pronounced for couplestresses as compared to nonconducting Newtonian fluid (NCNF) in the presence of magnetic field

Teacher and student views on the feasibility of peer to peer education as a model to educate 16–18 year olds on prudent antibiotic use—a qualitative study

Peer education (PE) has been used successfully to improve young peoples’ health-related behaviour. This paper describes a qualitative evaluation of the feasibility of university healthcare students delivering PE, covering self-care and antibiotic use for infections, to biology students in three UK schools (16–18 years), who then educated their peers. Twenty peer educators (PEds) participated in focus groups and two teachers took part in interviews to discuss PE feasibility. Data were analysed inductively. All participants reported that teaching students about antibiotic resistance was important. PE was used by PEds to gain communication skills and experience for their CV. PEds confidence increased with practice and group delivery. Interactive activities and real-life illness scenarios facilitated enjoyment. Barriers to PE were competing school priorities, no antibiotic content in the non-biology curriculum, controlling disruptive behaviour, and evaluation consent and questionnaire completion. Participation increased PEds’ awareness of appropriate antibiotic use. This qualitative study supports the feasibility of delivering PE in schools. Maximising interactive and illness scenario content, greater training and support for PEds, and inclusion of infection self-care and antibiotics in the national curriculum for all 16–18-year olds could help facilitate greater antibiotic education in schools. Simplifying consent and data collection procedures would facilitate future evaluations