22 research outputs found
Data Management Experiences and Best Practices from the Perspective of a Plant Research Institute
An application of spatial deconvolution to a capillary-based high-pressure chamber for fluorescence microscopy imaging
The influence of thickness in fatigue crack propagation rates in a low alloy steel weld metal above and below general yield
Application of GFP. Time-Lapse Multi-Wavelength Fluorescence Imaging of Living Malnnralian Cells.
Functional characterization of individual genomic condensin-binding sites in Saccharomyces cerevisiae using minichromosome mitotic segregation stability assay
Community Standards for Open Cell Migration Data
Cell migration research has become a high-content field. However, the quantitative information encapsulated in these complex and high-dimensional datasets is not fully exploited due to the diversity of experimental protocols and non-standardised output formats. In addition, typically the datasets are not open for reuse. Making the data open and Findable, Accessible, Interoperable, and Reusable (FAIR) will enable meta-analysis, data integration, and data mining. Standardised data formats and controlled vocabularies are essential for building a suitable infrastructure for that purpose but are not available in the cell migration domain. We here present standardisation efforts by the Cell Migration Standardisation Organization, CMSO, an open community-driven organisation to facilitate the development of standards for cell migration data. This work will foster the development of improved algorithms and tools, and enable secondary analysis of public datasets, ultimately unlocking new knowledge of the complex biological process of cell migration.Toxicolog