Polyetheretherketone (PEEK) for making bone implants in maxillofacial reconstruction surgery

Polyetheretherketone (P.EEK) has been used as a bone implant because it has the nature of a biocompatible, strong, non-corrosive, stable and not affected by high temperatures. PEEK is potential for use as an implant material. Applications in maxillofacial reconstruction surgery is very beneficial in terms of time and cost. Modelmaking mandible obtained from data on patients affected by tumor ameloblstoma. The data have been taken by a CT-scan in the form of DICOM (Digital Imaging and Communication in Medicine) is amended by Catya into STL files (stereolithography). STL file is then printed with 3D-printers and Computer Numerical Control (CNC) machines.Printouts based models have been created for the reconstruction implants in maxillofacial surgery

Neurofisiologi:Ereksi

v, 108 hlm.; 15x23 c

Awas jangan coba coba menjadi pengguna narkoba berbahaya

iv, 52 hlm.:Ilus.:16 c

Neurofisiologi: Ereksi

v, 108 hlm.; 23 c

Peranan Editor dalam Penerbitan Buku & Majalah Ilmiah

Untuk dapat membuat suatu paragraf yang baik, maka kita harus membuat suatu rencana yang sistematik mengenai isi buku, bab demi bab dan akhirnya baru kita tentukan paragraf demi paragrafnya. Cara berpikir sistematik mencerminkan kepribadian seorang sarjana. Dengan cara yang sistematik, maka tidak saja memudahkan bagi diri kita sendiri, tetapi akan memudahkan para pembacanya dalam memahami apa yang kita tulis itu

The impact of β-hCG on placental angiogenesis in pre-eclampsia

Numerous factors, such as VEGF and intra-placental oxygenation, can influence placental angiogenic activity. Early in the normal gestation period, β-hCG enhance VEGF activity to induce angiogenesis. The aims of this study were to identify the correlation between β-hCG concentration in placental culture and placental angiogenic activity in pre-eclampsia. Ten placenta samples from women with pre-eclampsia and l0 from controls (normal pregnancy) were collected. All subjects agreed to participate in this study and signed an informed consent form. β-hCG concentration in supernatant of placental culture was measured by Microparticle Enzyme Immunoassay (MEIA) and placental angiogenic activity was measured by endothelial cell migration toward placental explant (score 0-4). The results showed that the median score of placental angiogenic activity in pre-eclampsia was significantly higher than in normal pregnancy (p<0.05). Concentration of β-ahCG in pre-eclampsia was significantly higher than in normal pregnancy (p<0.001). hCG concentration in placental culture was positively correlated to placental angiogenic activity both in pre-eclampsia (r=+0.50) and in normal pregnancy (r=+0.57). Althouglt the correlations were weak, β-hCG is considered one of the factors that influence placental angiogenic activity. (Med J Indones 2005; 14: 67-70) Keyvords: angiogenesis, β-hCG, plocenta, pre-eclampsi

Interstitial cells of Cajal mediate mechanosensitive responses in the stomach

Changes in motor activity are a basic response to filling of smooth muscle organs. Responses to gastric filling, for example, are thought to be regulated by neural reflexes. Here, we demonstrate a previously uncharacterized aspect of stretch-dependent responses in visceral smooth muscles that is mediated by mechanosensitive interstitial cells of Cajal. Length ramps were applied to the murine antral muscles while recording intracellular electrical activity and isometric force. Stretching muscles by an average of 27 ± 1% of resting length resulted in 5 mN of force. Increasing length caused membrane depolarization and increased slow-wave frequency. The responses were dependent on the rate of stretch. Stretch-dependent responses were not inhibited by neuronal antagonists or nifedipine. Increases in slow-wave frequency, but not membrane depolarization, were inhibited by reducing external Ca(2+) (100 μM) and by Ni(2+) (250 μM). Responses to stretch were inhibited by indomethacin (1 μM) and were absent in cyclooxygenase II-deficient mice, suggesting that cyclooxygenase II-derived eicosanoids may mediate these responses. Dual microelectrode impalements of muscle cells within the corpus and antrum showed that stretch-induced changes in slow-wave frequency uncoupled proximal-to-distal propagation of slow waves. This uncoupling could interfere with gastric peristalsis and impede gastric emptying. Stretch of antral muscles of W/W(V) mice, which lack intramuscular interstitial cells of Cajal, did not affect membrane depolarization or slow-wave frequency. These data demonstrate a previously uncharacterized nonneural stretch reflex in gastric muscles and provide physiological evidence demonstrating a mechanosensitive role for interstitial cells of Cajal in smooth muscle tissues