21 research outputs found

    Innovation assessment in a local branch of a rail transport manufacture industry - A case study

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    Based on a poster submitted to CONCORD 2011 - Conference on Corporate R&D: The dynamics of Europe's industrial structure and the growth of innovative firms, Sevilla, IPTS, 6 Out. 2011, Seville, http://www.eventisimo.com/concord2011/recibido.htmlIn the context of the revitalization of the Portuguese railway sector with the construction of the high-speed railway network, the working paper proposes an analysis of the results found from the application of an innovation scoring to the Portuguese branch of a global multinational in the railway business. The aim of this exercise is to learn on the innovation management flow between the global corporation and the local branch in Portugal. It also aims to assess the degree of local innovation multinationals generate in view of such type of mega public investments. The working paper is structured in five chapters. In chapter one introduces the innovation scoring tool, instrument of work; chapter two covers the methodology used; the chapter tree presents the case study, subject of research; chapter four presents the findings; and chapter 5 closes with concluding remarks

    Innovation assessment of a Portuguese railway branch of a foreign multinational - a case study

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    Paper developed for the unit “Innovation Economics and Management” of the PhD programme in Technology Assessment at the Universidade Nova de Lisboa in 2009-10 under the supervision of Prof. Maria Luísa FerreiraThis paper analyses the application of the Innovation Scoring model and its results to the railway business branch of a foreign multinational. Results confirm some enrolment in non-core Research & Development connected to the commercial activity of selling trains. Two main determinants were found to support this enrolment: the impact of a new Portuguese law imposing R&D investment for public contracts; and a certain degree of openness in the multinational’s innovation strategy based on predictable growth for the Portuguese market. The study also confirms the usefulness of the Innovation Scoring model, leaving some suggestions for improvement such as tailoring for multi-decision centres, implementing it through a third party, reducing the number of questions and introduction of a product evaluation methodology

    Da selha da roupa à forma do bolo

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    Análise do processo de participação pública no projecto de Alta Velocidade Ferroviária

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    The study focuses on the public participation during the decision-making process of the High Speed Rail Project (popularly known as TGV) in Portugal. The study analyzes the media references on the topic and its actors in a quantitative and qualitative way from September 2008 to November 2009 anchored in the 2009 Legislatives and Local elections. The work concludes that despite the political polarization around the High Speed Rail Project, contributing to bring it to public debate, it didn’t allow for an improvement in qualitative information that could allow the emergence of an active and informed citizen participation in the debate.Trabalho entregue e avaliado na unidade “Métodos Interactivos de Participação e Decisão” do Programa Doutoral em Avaliação de Tecnologia na FCT-UN

    Investigação em Educação Matemática 2012: Práticas de ensino da Matemática

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    Esta revista inclui artigos sobre as práticas de sala de aula de professores de Matemática

    Poor Immune Reconstitution in HIV-Infected Patients Associates with High Percentage of Regulatory CD4(+) T Cells

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    CD4(+) regulatory T cells (Tregs) are essential for the maintenance of the immune system's equilibrium, by dampening the activation of potential auto-reactive T cells and avoiding excessive immune activation. To correctly perform their function, Tregs must be maintained at the right proportion with respect to effector T cells. Since this equilibrium is frequently disrupted in individuals infected with the human immunodeficiency virus (HIV), we hypothesize that its deregulation could hamper immune reconstitution in patients with poor CD4(+) T cell recovery under highly active antiretroviral therapy (HAART). We analysed Tregs percentages amongst CD4(+) T cells in 53 HIV-infected patients under HAART, with suppression of viral replication and distinct levels of immune reconstitution. As controls, 51 healthy individuals were also analysed. We observed that amongst the patients with Nadir values (the lowest CD4(+) T cell counts achieved) = 10% of total CD4(+) T cells) had the worse CD4(+) T cell reconstitution. In accordance, the well-described direct correlation between the Nadir value and CD4(+) T cell reconstitution is clearly more evident in individuals with high Tregs proportions. Furthermore, we observed a strong negative correlation between Tregs percentages and CD4(+) T cell recovery among immunological non-responder HIV+ individuals. All together, this work shows that high Tregs frequency is an important factor associated with sub-optimal CD4(+) T cell recovery. This is particularly relevant for immunological non-responders with low Nadir values. Our results suggest that the Tregs proportion might be of clinical relevance to define cut-offs for HAART initiation

    Innovation Assessment of a Portuguese Railway branch of a foreign multinational - A case study

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    This paper analyses the application of the Innovation Scoring model and its results to the railway business branch of a foreign multinational. Results confirm some enrolment in non-core Research & Development connected to the commercial activity of selling trains. Two main determinants were found to support this enrolment: the impact of a new Portuguese law imposing R&D investment for public contracts; and a certain degree of openness in the multinational’s innovation strategy based on predictable growth for the Portuguese market. The study also confirms the usefulness of the Innovation Scoring model, leaving some suggestions for improvement such as tailoring for multi-decision centres, implementing it through a third party, reducing the number of questions and introduction of a product evaluation methodology.Innovation Assessment; Railway; Policy; Scoring model; Multinational, Portugal

    Innovation assessment in a local branch of a rail transport manufacture industry - A case study

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    In the context of the revitalization of the Portuguese railway sector with the construction of the high-speed railway network, the working paper proposes an analysis of the results found from the application of an innovation scoring to the Portuguese branch of a global multinational in the railway business. The aim of this exercise is to learn on the innovation management flow between the global corporation and the local branch in Portugal. It also aims to assess the degree of local innovation multinationals generate in view of such type of mega public investments. The working paper is structured in five chapters. In chapter one introduces the innovation scoring tool, instrument of work; chapter two covers the methodology used; the chapter tree presents the case study, subject of research; chapter four presents the findings; and chapter 5 closes with concluding remarks.railway sector; Portugal; innovation scoring; global corporation

    Análise do processo de participação pública no projecto de Alta Velocidade Ferroviária [Analysis of the public participation process in the High-Speed Railway project]

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    The study focuses on the public participation during the decision-making process of the High Speed Rail Project (popularly known as TGV) in Portugal. The study analyzes the media references on the topic and its actors in a quantitative and qualitative way from September 2008 to November 2009 anchored in the 2009 Legislatives and Local elections. The work concludes that despite the political polarization around the High Speed Rail Project, contributing to bring it to public debate, it didn’t allow for an improvement in qualitative information that could allow the emergence of an active and informed citizen participation in the debate.High Speed Rail; Portugal; media; participative decision-making; leverage points
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