Keynote Address: What Transpires Now: Transgeder HIstory and the Future We Need

The 2017 keynote address presented by special guest Susan Stryker, Associate Professor of Gender and Women\u27s Studies at the University of Arizona. Professor Stryker is also the Director of the Institute for LGBT Studies, founder of the Transgender Studies Initiative, and holds a courtesy appointment as Associate Professor in the Norton School of Family and Consumer Sciences at the University of Arizona. She is the author of many articles and several books on transgender and queer topics, most recently Transgender History (Seal Press 2008). She won a Lambda Literary Award for the anthology The Transgender Studies Reader (Routledge 2006), and an Emmy Award for the documentary film Screaming Queens: The Riot at Compton\u27s Cafeteria (Frameline/ITVS 2005). Currently, she teaches classes on LGBT history, and on embodiment and technology at the University of Arizona. Research interests include transgender and queer studies, film and media, built environments, somatechnics, and critical theory

Minhas palavras para Victor Frankenstein acima da aldeia de Chamonix: Performar a fúria transgênera

A metáfora do monstro, frequentemente usada contra pessoas transgêneras, evoca aqui a fúria transgênera diante das interdições que defendem o binarismo sexual. Diversos gêneros textuais e tipos de conhecimento são usados para explorar aspectos da experiência trans

Ghost Dances: A Trans-Movement Manifesto

Several things coincided to shape the space from which this lecture emerged. The first was an email from a list I\u27m on, soliciting creative, artistic responses to climate change. The second was a call for proposals for a symposium on subversive imaginaries. The third, an ongoing conversation with a dancer friend about critical embodiment practices. Fourth, the tangle of thoughts sorting themselves out into various bits of prose and syllabi then being demanded by editors and administrators. Fifth, the backdrop of an historical presidential election soliciting us all to dwell upon the fierce urgency of now. And finally, the call from Sarah Chinn at CLAGS letting me know I\u27d have the honor and opportunity to pull something together to to say tonight: when she asked me for a title, Ghost Dances is what popped out

The differential effects of fructose and glucose on advanced glycation end-product formation and cellular damage in vitro

The protective mechanisms of microglia cells help to maintain central nervous system (CNS) homeostasis and function.1 Microglia are innate immune cells that constantly survey their surrounding CNS microenvironment for pathogens, damaged cells, and inflammatory molecules. Sugars from our diet, including glucose and fructose, combine with endogenous proteins non-enzymatically and form advanced glycation-end products (AGEs).2 AGEs are shown to produce reactive oxygen species, leading to inflammation and cellular damage that may be mediated by microglia.3 Fructose consumption has become increasingly prevalent within the American diet, as it is a lower cost sweetener.4 Microglia become activated and phagocytic in the presence of high levels of glucose, but the effects of fructose are not yet fully understood.3 The reactivity of fructose within the body and it’s long-term health implications remain unclear

Saberes (des)sujeitados: uma introdução aos estudos transgênero

Em 1995 eu me encontrava na fila, esperando minha vez para falar no microfone no Auditório Proshansky do Centro de Pós-Graduação da City University of New York. Estava participando de uma conferência chamada “História Lésbica e Gay”, organizada pelo Centro de Estudos Lésbicos e Gays (CLAGS). Eu havia acabado de assistir a um painel de debates sobre “gênero e o papel homossexual”, moderado por Randolph Trumbach e que tinha como palestrantes Will Roscoe, Martha Vicinus, George Chauncey, Ramon Gutierrez, Elizabeth Kennedy e Martin Manalansan. Ouvira muitas coisas interessantes sobre bichas e berdaches (como indígenas norte-americanes12 two-spirit ainda eram chamades), Corn Mothers3 e molly-houses4, amizades femininas passionais, díades butch-femme5, e a diáspora de gays do sudeste asiático, mas ainda assim estava de pé na fila para protestar. Cada ume des palestrantes era uma celebridade intelectual a seu modo, mas não eram, a meu ver, um grupo muito diverso em termos de gênero. Da minha perspectiva, com uma identidade transexual recém-reivindicada, todes elus pareciam um pouco a mesma coisa: pessoas não-transgênero. Uma nova onda de pesquisas transgênero, parte de um movimento intelectual queer mais amplo, já registrava alguns anos de vida naquele momento. Por que não havia palestrantes transgênero na discussão? Por que o debate inteiro sobre “diversidade de gênero” havia sido englobado por considerações sobre desejo sexual – como se o único motivo para expressar gênero fosse sinalizar os modos de atração e disponibilidade de uma pessoa para potenciais parceires sexuais

Case study of a performance-active changing trans* male singing voice

A professional classical singer of more than 25 years (AZ) in his early 50s requested this voice researcher’s consultation and assistance in early 2014. He was about to start living full time as a trans* man. Despite his intention to be included in the low start/gradual increase testosterone option of the Trans* Male (previously, “FTM”) Singing Voice Program, the request contained a rather unconventional aspect: AZ would continue to sing while his voice was changing. The above request was integral with his singing history. After the introduction of safeguards and his informed consent, AZ was accepted onto the Program. Due to the highly individual circumstances, his participation was recorded as a case study. The study has aimed to replicate the particulars of the slow hormonal changes and continuing singing ability found in certain cisgender male adolescent voices. Despite dealing with an adult trans* male individual, the progress has been comparable. This has been achieved by carefully monitoring AZ’s low start/gradual increase testosterone administration in communication with the medical practitioner. The participant’s vocal health remained safeguarded and promoted by carefully individualized vocal tuition. This article will discuss the collective results of the case study, including the recordings and the data analysis

Activism, affect, identification: trans documentary in France and Spain and its reception

This article explores the documentation of trans activism in France and Spain since the 2000s. The first part addresses questions surrounding the place of affect and narrative in documentary film, particularly in relation to trans issues. The second part o f the article analyses an audience case study from a screening at the International Gay and Lesbian Film Festival in Barcelona of Valérie Mitteaux's Girl or Boy, My Sex is not my Gender (2011), considering how different viewers respond to the representatio n of trans identities. The article builds on qualitative research whilst extending the exploration of sexuality and gender in previous audience studies to a consideration of documentary film, seeking to provide a more nuanced understanding of what audience claims for identification in politicised contexts mean

Sustained mucosal colonization and fecal metabolic dysfunction by Bacteroides associates with fecal microbial transplant failure in ulcerative colitis patients.

Fecal microbial transplantation (FMT) offers promise for treating ulcerative colitis (UC), though the mechanisms underlying treatment failure are unknown. This study harnessed longitudinally collected colonic biopsies (n = 38) and fecal samples (n = 179) from 19 adults with mild-to-moderate UC undergoing serial FMT in which antimicrobial pre-treatment and delivery mode (capsules versus enema) were assessed for clinical response (≥ 3 points decrease from the pre-treatment Mayo score). Colonic biopsies underwent dual RNA-Seq; fecal samples underwent parallel 16S rRNA and shotgun metagenomic sequencing as well as untargeted metabolomic analyses. Pre-FMT, the colonic mucosa of non-responsive (NR) patients harbored an increased burden of bacteria, including Bacteroides, that expressed more antimicrobial resistance genes compared to responsive (R) patients. NR patients also exhibited muted mucosal expression of innate immune antimicrobial response genes. Post-FMT, NR and R fecal microbiomes and metabolomes exhibited significant divergence. NR metabolomes had elevated concentrations of immunostimulatory compounds including sphingomyelins, lysophospholipids and taurine. NR fecal microbiomes were enriched for Bacteroides fragilis and Bacteroides salyersiae strains that encoded genes capable of taurine production. These findings suggest that both effective mucosal microbial clearance and reintroduction of bacteria that reshape luminal metabolism associate with FMT success and that persistent mucosal and fecal colonization by antimicrobial-resistant Bacteroides species may contribute to FMT failure

2017 American College of Rheumatology/American Association of Hip and Knee Surgeons Guideline for the Perioperative Management of Antirheumatic Medication in Patients With Rheumatic Diseases Undergoing Elective Total Hip or Total Knee Arthroplasty

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/137753/1/acr23274.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/137753/2/acr23274_am.pd