PERSEPSI TENTANG FAKTOR-FAKTOR YANG MEMPENGARUHI KORUPSI (STUDI PADA SKPD DI KOTA BANDA ACEH)

ABSTRAKPenelitian ini bertujuan untuk mengetahui dan menganalisis bahwa perilaku individu, kelembagaan pemerintah daerah, penerapan perundang-undangan serta pengawasan mempengaruhi terjadinya perilaku korupsi di SKPD Kota Banda Aceh. Data yang digunakan adalah data primer berupa persepsi responden pada SKPD di Kota Banda. Penelitian ini adalah kualitatif, yang menjadi objek penelitian ini adalah 27 SKPD di Kota Banda Aceh. Metode analisis yang digunakan dalam penelitian ini adalah regresi linear, Data diolah dengan menggunakan program Softwere Statistic Product and Service Solution (SPSS versi 22). Hasil penelitian ini menunjukan bahwa jika perilaku individu, kelembagaan pemerintah daerah, peraturan perundang-undangan, dan pengawasan tidak mengalami perubahan atau diasumsikan sudah berjalan dengan normal, maka perilaku korupsi di SKPD Kota Banda Aceh secara konstan hanya berpeluang terjadi sebesar -02.785 pada standar skala likert.Kata Kunci: Perilaku individu, kelembagaan pemerintah daerah, penerapan perundang-undangan, pengawasan dan perilaku korupsi

At home in the margins

n/

PROMOSI DINAS KEBUDAYAAN PARIWISATA PEMUDA DAN OLAHRAGA DALAM MENJADIKAN KOTA TAPAKTUAN SEBAGAI KOTA PARIWISATA

Banda Ace

CTLA4 gene polymorphisms in autoimmune hepatitis (AIH) : gene and clinical disease correlations in South African patients

Also available online. Includes bibliographical references (leaves 76-85)

The triphenylmethane dye brilliant blue G is only moderately effective at inhibiting amyloid formation by human amylin or at disaggregating amylin amyloid fibrils, but interferes with amyloid assays; Implications for inhibitor design.

The development of inhibitors of islet amyloid formation is important as pancreatic amyloid deposition contributes to type-2 diabetes and islet transplant failure. The Alzheimer's Aβ peptide and human amylin (h-amylin), the polypeptide responsible for amyloid formation in type-2 diabetes, share common physio-chemical features and some inhibitors of Aβ also inhibit amyloid formation by h-amylin and vice versa. Thus, a popular and potentially useful strategy to find lead compounds for anti-amylin amyloid agents is to examine compounds that have effects on Aβ amyloid formation. The triphenylmethane dye, brilliant blue G (BBG, Sodium;3-[[4-[(E)-[4-(4-ethoxyanilino)phenyl]-[4-[ethyl-[(3-sulfonatophenyl)methyl]azaniumylidene]-2-methylcyclohexa-2,5-dien-1-ylidene]methyl]-N-ethyl-3-methylanilino]methyl]benzenesulfonate) has been shown to modulate Aβ amyloid formation and inhibit Aβ induced toxicity. However, the effects of BBG on h-amylin have not been examined, although other triphenylmethane derivatives inhibit h-amylin amyloid formation. The compound has only a modest impact on h-amylin amyloid formation unless it is added in significant excess. BBG also remodels preformed h-amylin amyloid fibrils if added in excess, however BBG has no significant effect on h-amylin induced toxicity towards cultured β-cells or cultured CHO-T cells except at high concentrations. BBG is shown to interfere with standard thioflavin-T assays of h-amylin amyloid formation and disaggregation, highlighting the difficulty of interpreting such experiments in the absence of other measurements. BBG also interferes with ANS based assays of h-amylin amyloid formation. The work highlights the differences between inhibition of Aβ and h-amylin amyloid formation, illustrates the limitation of using Aβ inhibitors as leads for h-amylin amyloid inhibitors, and reinforces the difficulties in interpreting dye binding assays of amyloid formation

Cluster formation during aging of colloid-polymer dispersions and re-entrant rheological behavior at interfaces and the microscale

We report the dynamics of aqueous dispersions of the disk-shaped colloidal clay laponite® with poly(ethylene oxide) (PEO) chains of moderate molecular weight, explored via angle-dependent dynamic light scattering (DLS), bulk rheology, passive microrheology, and interfacial rheology. The PEO chains adsorb onto the laponite® surfaces, causing interesting dynamic behavior, including transitions from arrested states to liquid states as the concentration and molecular weight of PEO is increased. This re-entrant behavior has been attributed to formation of particle clusters induced free PEO chains. Our DLS results are consistent with a slow diffusive dynamic process, suggesting the formation of large particle clusters, in samples at aging times \u3c 75 days (Figure 1). By contrast to behavior observed in laponite® dispersions with a non-adsorbing polymer, poly(acrylic acid) (PAA), diffusion coefficients of these clusters in the laponite®-PEO systems continue to decrease with aging time until samples reach an arrested state. Finally, interfacial rheology and passive microrheology also show some evidence of re-entrant behavior, although the polymer concentrations at which this occurs do not exactly correspond to the conditions under which re-entrant behavior is observed in bulk rheology Please click Additional Files below to see the full abstract

Formulation and Evaluation of Pulsatile Drug Delivery System of Atenolol

The objective of the present study was formulation and evaluation of pulsatile release tablets of Atenolol. A tablet system consisting of cores which was coated with layers of swelling and rupturable coatings. Cores containing Atenolol as model drug were prepared by direct compression with appropriate ratios of lactose and microcrystalline cellulose and then coated sequentially with different ratios of an inner swelling layer containing HPMC and an outer rupturable layer of Ethyl Cellulose. The effect of level of swelling layer and rupturable coating was investigated. The different formulation press coated by using different weight ratios of Hydroxy Propyl Methyl Cellulose (HPMC) / Ethyl Cellulose (EC) / both HPMC and EC. The optimum result was achieved in formulation containing HPMC: EC weight ratios. The F3 batch achieved a highest burst release after the lag time which is applicable pulsatile drug delivery system of Atenolol

FINITE ELEMENT ANALYSIS FOR OPTIMIZING ANTENNA FOR MICROWAVE COAGULATION THERAPY

Microwave coagulation therapy (MCT) is emerging as an attractive modality for thermal therapy of soft tissues targeted in short periods of time, making it particularly suitable for ablation of hepatic and other tumors. In this field of microwave coagulation therapy, the use of minimally invasive antenna is recognized as a very promising technique for the treatment of small tumors because a very thin antenna can be easily inserted inside the body and precisely localized using the advanced 3D imaging techniques and surgical robots. The authors investigated the microwave coaxial antenna operating at 2.45 GHz by varying the slots size for the removal of liver tumor. The analysis was done using 2D finite element modeling. By several optimization steps the antenna is simulated and optimized by comparing the values of specific absorption rate (SAR), mesh statistics and temperature distributions in tissue generated by the antenna with the variations of dimensions of slot from 1 mm to 1.7 mm

LATIHAN SENAM AEROBIK DALAM MENURUNKAN BERAT BADAN PADA IBU DENGAN EFEK SAMPING PENGGUNA ALAT KONTRASEPSI SUNTIK DI WILAYAH KERJA PUSKESMAS MULYOREJO KECAMATAN SUNGGAL KABUPATEN DELI SERDANG

Kontrasepsi adalah usaha untuk mencegah terjadinya kehamilan yang dapat bersifat sementara atau permanen. Salah satu alat kontrasepsi yang berdaya kerja panjang, aman, dapat diandalkan, sederhana, murah dan dapat diterima orang banyak adalah alat kontrasepsi efektif jangka pendek jenis hormonal yaitu suntikan (injectables). Tujuan dari pengabdian masyarakat ini adalah untuk meningkatkan pengetahuan ibu, yaitu bagaimana cara menurunkan berat badan dengan melakukan latihan senam aerobik. Metode yang dilakukan dengan pendidikan kesehatan dan melakukan latihan senam aerobik. Dari hasil pre test sebelum dilakukan latihan senam diperoleh hasil pengetahuan baik sebanyak 13 orang (43,33%), pengetahuan tidak baik 17 orang (56,67%) dan hasil post test setelah dilakukan latihan senam pengetahuan baik sebanyak 23 orang (76,67%), pengetahuan tidak baik 7 orang (23,33%). Setelah dilakukan latihan senam aerobik ada terjadi perubahan berat badan pada ibu 9 orang (30%), hal ini disebabkan karna masih banyak ibu yang belum memanfaatkan latihan senam aerobik ini. Diharapkan kepada ibu-ibu untuk tetap antusias dan terus melakukan latihan senam aerobik secara mandiri sesuai SOP dan dapat mengaplikasikan latihan senam aerobik ini untuk diri sendiri sebagai salah satu cara untuk menurunkan berat badan ibu dari efek penggunaan alat kontrasepsi suntik. Kepada kader dan petugas kesehatan di Puskesmas Mulyorejo diharapkan untuk tetap melanjutkan latihan senam aerobik ini pada ibu-ibu setiap 3 kali seminggu