1,361 research outputs found

    An quantum approach of measurement based on the Zurek's triple model

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    In a close form without referring the time-dependent Hamiltonian to the total system, a consistent approach for quantum measurement is proposed based on Zurek's triple model of quantum decoherence [W.Zurek, Phys. Rev. D 24, 1516 (1981)]. An exactly-solvable model based on the intracavity system is dealt with in details to demonstrate the central idea in our approach: by peeling off one collective variable of the measuring apparatus from its many degrees of freedom, as the pointer of the apparatus, the collective variable de-couples with the internal environment formed by the effective internal variables, but still interacts with the measured system to form a triple entanglement among the measured system, the pointer and the internal environment. As another mechanism to cause decoherence, the uncertainty of relative phase and its many-particle amplification can be summed up to an ideal entanglement or an Shmidt decomposition with respect to the preferred basis.Comment: 22pages,3figure

    Surgical excision promotes tumor growth and metastasis by promoting expression of MMP-9 and VEGF in a breast cancer model

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    Surgery is still the main curative therapeutic modality for breast cancer. Although surgery often results in the successful removal of the primary tumor, its process could increase the risk of metastases of residual cancer cells. Understanding of the connection between breast cancer metastasis and surgical wound will lead to the establishment of a proper treatment strategy for postoperative cancer patient. Aim: To study the influence of surgical procedure on the metastasis of primary breast cancer. Methods: We established MDA-MB-435 human breast cancer xenograft model. Levels of Pro-matrix metalloproteinase 9 (Pro-MMP-9) and vascular endothelial growth factor (VEGF) in host serum and tumors were tested at different time points with ELISA and zymography and correlated to tumor growth and postoperative metastasis. Results: Our study demonstrated surgical wound had promoting effect on tumor growth and pulmonary metastasis of human breast cells, if tumor cells remain in bodies. This effect might be related to the postoperative interaction of cancer and host cells, which resulted in expression of Pro-MMP-9. Surgical process could also increase the VEGF expression in tumor tissues. Conclusions: Surgical wound-produced host Pro-MMP-9 and tumor cell VEGF might be important mediators leading to metastasis of residual breast cancer after surgery.Π₯ирургичСскоС Π»Π΅Ρ‡Π΅Π½ΠΈΠ΅ Π΄ΠΎ сих ΠΏΠΎΡ€ остаСтся Π³Π»Π°Π²Π½Ρ‹ΠΌ тСрапСвтичСским ΠΏΠΎΠ΄Ρ…ΠΎΠ΄ΠΎΠΌ ΠΏΡ€ΠΈ Π»Π΅Ρ‡Π΅Π½ΠΈΠΈ Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… Ρ€Π°ΠΊΠΎΠΌ ΠΌΠΎΠ»ΠΎΡ‡Π½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ‹. Π₯отя хирургичСскоС ΡƒΠ΄Π°Π»Π΅Π½ΠΈΠ΅ ΠΎΠΏΡƒΡ…ΠΎΠ»ΠΈ Π² Π±ΠΎΠ»ΡŒΡˆΠΈΠ½ΡΡ‚Π²Π΅ случаСв достаточно эффСктивно, Π² Ρ‚ΠΎ ΠΆΠ΅ врСмя ΠΎΠ½ΠΎ ΠΌΠΎΠΆΠ΅Ρ‚ ΡƒΠ²Π΅Π»ΠΈΡ‡ΠΈΡ‚ΡŒ риск мСтастазирования остаточных ΠΎΠΏΡƒΡ…ΠΎΠ»Π΅Π²Ρ‹Ρ… ΠΊΠ»Π΅Ρ‚ΠΎΠΊ. ПониманиС связи ΠΌΠ΅ΠΆΠ΄Ρƒ мСтастазированиСм ΠΏΡ€ΠΈ Ρ€Π°ΠΊΠ΅ ΠΌΠΎΠ»ΠΎΡ‡Π½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ‹ ΠΈ ΠΎΠΏΠ΅Ρ€Π°Ρ†ΠΈΠΎΠ½Π½ΠΎΠΉ Ρ€Π°Π½ΠΎΠΉ ΠΏΠΎΠ·Π²ΠΎΠ»ΠΈΡ‚ Π²Ρ‹Π±Ρ€Π°Ρ‚ΡŒ Π½Π°ΠΈΠ»ΡƒΡ‡ΡˆΡƒΡŽ ΡΡ‚Ρ€Π°Ρ‚Π΅Π³ΠΈΡŽ постопСрационного лСчСния. ЦСль: ΠΎΠΏΡ€Π΅Π΄Π΅Π»ΠΈΡ‚ΡŒ влияниС хирургичСского Π²ΠΌΠ΅ΡˆΠ°Ρ‚Π΅Π»ΡŒΡΡ‚Π²Π° Π½Π° мСтастазированиС ΠΎΠΏΡƒΡ…ΠΎΠ»ΠΈ. ΠœΠ΅Ρ‚ΠΎΠ΄Ρ‹: Π±Ρ‹Π»Π° создана модСль Ρ€Π°ΠΊΠ° ΠΌΠΎΠ»ΠΎΡ‡Π½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ‹ Ρ‡Π΅Π»ΠΎΠ²Π΅ΠΊΠ° Π² Π²ΠΈΠ΄Π΅ ксСнотрансплантата MDA-MB-435. Π£Ρ€ΠΎΠ²Π΅Π½ΡŒ Pro-ΠΌΠ°Ρ‚Ρ€ΠΈΡ‡Π½ΠΎΠΉ ΠΌΠ΅Ρ‚Π°Π»Π»ΠΎΠΏΡ€ΠΎΡ‚Π΅ΠΈΠ½Π°Π·Ρ‹ 9 (Pro-MMP-9) ΠΈ Ρ„Π°ΠΊΡ‚ΠΎΡ€Π° роста эндотСлия сосудов (VEGF) Π² сывороткС Ρ€Π΅Ρ†ΠΈΠΏΠΈΠ΅Π½Ρ‚Π° ΠΈ опухолях ΠΎΡ†Π΅Π½ΠΈΠ²Π°Π»ΠΈΡΡŒ Π² Ρ€Π°Π·Π½Ρ‹Π΅ Π²Ρ€Π΅ΠΌΠ΅Π½Π½Ρ‹Π΅ ΠΏΡ€ΠΎΠΌΠ΅ΠΆΡƒΡ‚ΠΊΠΈ ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΎΠΌ ELISA ΠΈ Π·ΠΈΠΌΠΎΠ³Ρ€Π°Ρ„ΠΈΠΈ. ΠŸΡ€ΠΈ этом опрСдСляли Π½Π°Π»ΠΈΡ‡ΠΈΠ΅ корСлляции ΠΌΠ΅ΠΆΠ΄Ρƒ этими ΠΏΠΎΠΊΠ°Π·Π°- ΠΈ Π·ΠΈΠΌΠΎΠ³Ρ€Π°Ρ„ΠΈΠΈ. ΠŸΡ€ΠΈ этом опрСдСляли Π½Π°Π»ΠΈΡ‡ΠΈΠ΅ корСлляции ΠΌΠ΅ΠΆΠ΄Ρƒ этими ΠΏΠΎΠΊΠ°Π·Π° ΠΈ Π·ΠΈΠΌΠΎΠ³Ρ€Π°Ρ„ΠΈΠΈ. ΠŸΡ€ΠΈ этом опрСдСляли Π½Π°Π»ΠΈΡ‡ΠΈΠ΅ корСлляции ΠΌΠ΅ΠΆΠ΄Ρƒ этими показатСлями, ростом ΠΎΠΏΡƒΡ…ΠΎΠ»ΠΈ ΠΈ постопСрационными мСтастазами. Π Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹: Π±Ρ‹Π»ΠΎ ΠΏΠΎΠΊΠ°Π·Π°Π½ΠΎ, Ρ‡Ρ‚ΠΎ опСрационная Ρ€Π°Π½Π° способствуСт росту ΠΎΠΏΡƒΡ…ΠΎΠ»ΠΈ ΠΌΠΎΠ»ΠΎΡ‡Π½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ‹ ΠΈ Π΅Π΅ ΠΌΠ΅Ρ‚Π°ΡΡ‚Π°Π·ΠΈΡ€ΠΎΠ²Π°Π½ΠΈΡŽ Π² Π»Π΅Π³ΠΊΠΈΠ΅ Π² случаС, ΠΊΠΎΠ³Π΄Π° ΠΏΡ€ΠΈ ΡƒΠ΄Π°Π»Π΅Π½ΠΈΠΈ ΠΎΠΏΡƒΡ…ΠΎΠ»ΠΈ Π² Ρ€Π°Π½Π΅ ΠΎΡΡ‚Π°ΡŽΡ‚ΡΡ ΠΎΠΏΡƒΡ…ΠΎΠ»Π΅Π²Ρ‹Π΅ ΠΊΠ»Π΅Ρ‚ΠΊΠΈ. Π­Ρ‚ΠΎ ΠΌΠΎΠΆΠ΅Ρ‚ Π±Ρ‹Ρ‚ΡŒ связано с постопСрационным взаимодСйствиСм ΠΎΠΏΡƒΡ…ΠΎΠ»Π΅Π²Ρ‹Ρ… ΠΈ ΠΎΠΊΡ€ΡƒΠΆΠ°ΡŽΡ‰ΠΈΡ… ΠΈΡ… Π½ΠΎΡ€ΠΌΠ°Π»ΡŒΠ½Ρ‹Ρ… ΠΊΠ»Π΅Ρ‚ΠΎΠΊ, ΠΊΠΎΡ‚ΠΎΡ€ΠΎΠ΅ ΠΏΡ€ΠΈΠ²ΠΎΠ΄ΠΈΡ‚ ΠΊ экспрСссии Pro-MMP-9. Π£Π΄Π°Π»Π΅Π½ΠΈΠ΅ ΠΎΠΏΡƒΡ…ΠΎΠ»ΠΈ ΠΌΠΎΠΆΠ΅Ρ‚ Ρ‚Π°ΠΊΠΆΠ΅ ΡΠΏΠΎΡΠΎΠ±ΡΡ‚Π²ΠΎΠ²Π°Ρ‚ΡŒ ΡƒΠ²Π΅Π»ΠΈΡ‡Π΅Π½ΠΈΡŽ экспрСссии VEGF ΠΎΠΏΡƒΡ…ΠΎΠ»Π΅Π²Ρ‹ΠΌΠΈ ΠΊΠ»Π΅Ρ‚ΠΊΠ°ΠΌΠΈ. Π’Ρ‹Π²ΠΎΠ΄Ρ‹: Pro-MMP-9, экспрСссируСмый Π½ΠΎΡ€ΠΌΠ°Π»ΡŒΠ½Ρ‹ΠΌΠΈ ΠΊΠ»Π΅Ρ‚ΠΊΠ°ΠΌΠΈ, ΠΎΠΊΡ€ΡƒΠΆΠ°ΡŽΡ‰ΠΈΠΌΠΈ ΠΏΠΎΡΡ‚ΠΎΠΏΠ΅Ρ€Π°Ρ†ΠΈΠΎΠ½Π½ΡƒΡŽ Ρ€Π°Π½Ρƒ, Π° Ρ‚Π°ΠΊΠΆΠ΅ VEGF, ΠΏΡ€ΠΎΠ΄ΡƒΡ†ΠΈΡ€ΡƒΠ΅ΠΌΡ‹ΠΉ ΠΎΠΏΡƒΡ…ΠΎΠ»Π΅Π²Ρ‹ΠΌΠΈ ΠΊΠ»Π΅Ρ‚ΠΊΠ°ΠΌΠΈ, ΠΌΠΎΠ³ΡƒΡ‚ Π±Ρ‹Ρ‚ΡŒ Π²Π°ΠΆΠ½Ρ‹ΠΌΠΈ ΠΌΠ΅Π΄ΠΈΠ°Ρ‚ΠΎΡ€Π°ΠΌΠΈ мСтастазирования остаточных ΠΎΠΏΡƒΡ…ΠΎΠ»Π΅Π²Ρ‹Ρ… ΠΊΠ»Π΅Ρ‚ΠΎΠΊ послС хирургичСского Π²ΠΌΠ΅ΡˆΠ°Ρ‚Π΅Π»ΡŒΡΡ‚Π²Π°

    Superconductivity and single crystal growth of Ni0:05TaS2

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    Superconductivity was discovered in a Ni0:05TaS2 single crystal. A Ni0:05TaS2 single crystal was successfully grown via the NaCl/KCl flux method. The obtained lattice constant c of Ni0:05TaS2 is 1.1999 nm, which is significantly smaller than that of 2H-TaS2 (1.208 nm). Electrical resistivity and magnetization measurements reveal that the superconductivity transition temperature of Ni0:05TaS2 is enhanced from 0.8 K (2H-TaS2) to 3.9 K. The charge-density-wave transition of the matrix compound 2H-TaS2 is suppressed in Ni0:05TaS2. The success of Ni0:05TaS2 single crystal growth via a NaCl/KCl flux demonstrates that NaCl/KCl flux method will be a feasible method for single crystal growth of the layered transition metal dichalcogenides.Comment: 13pages, 6 figures, Published in SS

    Properties and Applications of the Electrohydraulic Servosystem of the Hydraulic Excavator

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    The service of a hydraulic excavator is complicated by poor environment. The safety and stability of the control system are influenced by external factors. The object of the study is the electrohydraulic servosystem of the hydraulic excavator. The mathematical and simulation models using AMESIM for the servosystem are constructed. Then the pressure and flow characteristics are analyzed. The design and optimization of the electrohydraulic servosystem and its application in excavator engineering are described. The operation process is graphically presented by a curve, which steeply slopes up (rising period) and then flattens out (stabilization period), those periods are shortened by 38.0 and 40.5%, respectively, the delay tracking period decreased by 52.6%, and anti-interference is reliable.Эксплуатация гидравличСского экскаватора ослоТняСтся Π½Π°Π»ΠΈΡ‡ΠΈΠ΅ΠΌ нСблагоприятной Ρ€Π°Π±ΠΎΡ‡Π΅ΠΉ срСды. Показано воздСйствиС Π²Π½Π΅ΡˆΠ½ΠΈΡ… Ρ„Π°ΠΊΡ‚ΠΎΡ€ΠΎΠ² Π½Π° Π½Π°Π΄Π΅ΠΆΠ½ΠΎΡΡ‚ΡŒ ΠΈ ΡΡ‚Π°Π±ΠΈΠ»ΡŒΠ½ΠΎΡΡ‚ΡŒ систСмы контроля. ИсслСдована элСктрогидравличСская сСрвосистСма гидравличСского экскаватора. ΠŸΠΎΡΡ‚Ρ€ΠΎΠ΅Π½Ρ‹ матСматичСская ΠΈ имитационная ΠΌΠΎΠ΄Π΅Π»ΠΈ для сСрвосистСмы с использованиСм ΠΏΡ€ΠΎΠ³Ρ€Π°ΠΌΠΌΡ‹ AMESIM. Π’Ρ‹ΠΏΠΎΠ»Π½Π΅Π½ Π°Π½Π°Π»ΠΈΠ· характСристик давлСния ΠΈ тСкучСсти. ΠžΠΏΠΈΡΠ°Π½Ρ‹ конструкция ΠΈ оптимизация элСктрогидравличСской сСрвосистСмы, Π° Ρ‚Π°ΠΊΠΆΠ΅ Π΅Π΅ ΠΏΡ€ΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ Π² экскаваторной Ρ‚Π΅Ρ…Π½ΠΈΠΊΠ΅. ΠŸΡ€ΠΎΡ†Π΅ΡΡ функционирования элСктрогидравличСской сСрвосистСмы прСдставлСн ΠΊΡ€ΠΈΠ²ΠΎΠΉ, которая ΠΊΡ€ΡƒΡ‚ΠΎ ΠΈΠ΄Π΅Ρ‚ Π²Π²Π΅Ρ€Ρ… (ΠΏΠ΅Ρ€ΠΈΠΎΠ΄ подъСма), Π° Π·Π°Ρ‚Π΅ΠΌ Π²Ρ‹Ρ…ΠΎΠ΄ΠΈΡ‚ Π½Π° ΠΏΠ»Π°Ρ‚ΠΎ (ΠΏΠ΅Ρ€ΠΈΠΎΠ΄ стабилизации), эти ΠΏΠ΅Ρ€ΠΈΠΎΠ΄Ρ‹ ΡΠΎΠΊΡ€Π°Ρ‰Π°ΡŽΡ‚ΡΡ Π½Π° 38,0 ΠΈ 40,5% соотвСтствСнно, ΠΏΠ΅Ρ€ΠΈΠΎΠ΄ слСТСния Π·Π° Π·Π°Π΄Π΅Ρ€ΠΆΠΊΠΎΠΉ Π½Π° 52,6% ΠΏΡ€ΠΈ эффСктивной помСхоустойчивости

    Effect of magnetic and non-magnetic impurities on highly anisotropic superconductivity

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    We generalize Abrikosov-Gor'kov solution of the problem of weakly coupled superconductor with impurities on the case of a multiband superconductor with arbitrary interband order parameter anisotropy, including interband sign reversal of the order parameter. The solution is given in terms of the effective (renormalized) coupling matrix and describes not only TcT_c suppression but also renormalization of the superconducting gap basically at all temperatures. In many limiting cases we find analytical solutions for the critical temperature suppression. We illustrate our results by numerical calculations for two-band model systems.Comment: 18 pages (12pt) RevTeX, 4 postscript figure

    Influence of a Uniform Current on Collective Magnetization Dynamics in a Ferromagnetic Metal

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    We discuss the influence of a uniform current, jβƒ—\vec{j} , on the magnetization dynamics of a ferromagnetic metal. We find that the magnon energy Ο΅(qβƒ—)\epsilon(\vec{q}) has a current-induced contribution proportional to qβƒ—β‹…Jβƒ—\vec{q}\cdot \vec{\cal J}, where Jβƒ—\vec{\cal J} is the spin-current, and predict that collective dynamics will be more strongly damped at finite jβƒ—{\vec j}. We obtain similar results for models with and without local moment participation in the magnetic order. For transition metal ferromagnets, we estimate that the uniform magnetic state will be destabilized for j≳109Acmβˆ’2j \gtrsim 10^{9} {\rm A} {\rm cm}^{-2}. We discuss the relationship of this effect to the spin-torque effects that alter magnetization dynamics in inhomogeneous magnetic systems.Comment: 12 pages, 2 figure

    Quantum discord evolution of three-qubit states under noisy channels

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    We investigated the dissipative dynamics of quantum discord for correlated qubits under Markovian environments. The basic idea in the present scheme is that quantum discord is more general, and possibly more robust and fundamental, than entanglement. We provide three initially correlated qubits in pure Greenberger-Horne-Zeilinger (GHZ) or W state and analyse the time evolution of the quantum discord under various dissipative channels such as: Pauli channels Οƒx\sigma_{x}, Οƒy\sigma_{y}, and Οƒz\sigma_{z}, as well as depolarising channels. Surprisingly, we find that under the action of Pauli channel Οƒx\sigma_{x}, the quantum discord of GHZ state is not affected by decoherence. For the remaining dissipative channels, the W state is more robust than the GHZ state against decoherence. Moreover, we compare the dynamics of entanglement with that of the quantum discord under the conditions in which disentanglement occurs and show that quantum discord is more robust than entanglement except for phase flip coupling of the three qubits system to the environment.Comment: 17 pages, 4 figures, accepted for publication in EPJ
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