Consolidating digital servitization research : A systematic review, integrative framework, and future research directions

Manufacturing firms are increasingly transforming toward digital servitization, characterized by convergence and simultaneous gains from digitalization and servitization. Due to the marked academic and practical relevance of digital servitization, we are witnessing a significant upsurge in studies published on this emerging topic. Thus, the present study undertakes a comprehensive bibliometric analysis to synthesize the prior knowledge on digital servitization and, more importantly, to highlight areas for future research. The findings from the analysis are organized so that important authors and organizations are highlighted through analyses of citation chains and co-authorship networks. The bibliographic coupling analysis of HistCite and VOSviewer reveals the emergence of four dominant thematic areas in the digital servitization literature. These four thematic areas are aligning digitalization and servitization transformations, value co-creation perspectives on digital servitization, conceptualizing the platform strategy for digital servitization, and business model innovation in digital servitization. Finally, based on the analysis of how the literature on digital servitization has evolved over the last two decades and the deeper analysis of thematic analysis, we raise important research questions and provide numerous areas for future research.© 2023 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).fi=vertaisarvioitu|en=peerReviewed

Genomic monitoring of SARS-CoV-2 uncovers an Nsp1 deletion variant that modulates type I interferon response

The SARS-CoV-2 virus, the causative agent of COVID-19, is undergoing constant mutation. Here, we utilized an integrative approach combining epidemiology, virus genome sequencing, clinical phenotyping, and experimental validation to locate mutations of clinical importance. We identified 35 recurrent variants, some of which are associated with clinical phenotypes related to severity. One variant, containing a deletion in the Nsp1-coding region (D500-532), was found in more than 20% of our sequenced samples and associates with higher RT-PCR cycle thresholds and lower serum IFN-beta levels of infected patients. Deletion variants in this locus were found in 37 countries worldwide, and viruses isolated from clinical samples or engineered by reverse genetics with related deletions in Nsp1 also induce lower IFN-beta responses in infected Calu-3 cells. Taken together, our virologic surveillance characterizes recurrent genetic diversity and identified mutations in Nsp1 of biological and clinical importance, which collectively may aid molecular diagnostics and drug design.Peer reviewe

Pollution and Cleaning of PDMS Pervaporation Membranes after Recovering Ethyl Acetate from Aqueous Saline Solutions

The removal of volatile organic compounds (VOCs) from wastewater containing nonvolatile salts has become an important and interesting case of the application of the pervaporation (PV) process. The aim of this study was to evaluate the influence of salts on the PV removal of ethyl acetate from wastewater using a polydimethylsiloxane (PDMS) membrane. The fouled membrane was then characterized via scanning electron microscopy–energy-dispersive X-ray analysis (SEM–EDX) to investigate salt permeation. The membrane backflushing process was carried out by periodically flushing the permeate side of the tubular membrane. The results demonstrated that salts (NaCl and CaCl2) could permeate through the PDMS membrane and were deposited on the permeate side. The presence of salts in the feed solution caused a slight increase in the membrane selectivity and a decrease in the permeate flux. The flux decreased with increasing salt concentration, and a notable effect occurred at higher feed-salt concentrations. A permeate flux of up to 98.3% of the original flux was recovered when the permeation time and backflushing duration were 30 and 5 min, respectively, indicating that the effect of salt deposition on flux reduction could be mitigated. Real, organic, saline wastewater was treated in a pilot plant, which further verified the feasibility of wastewater PV treatment

Recent advances in non-metal modification of graphitic carbon nitride for photocatalysis: A historic review

Photocatalysis is a green, feasible and versatile technology that has been widely used for energy conversion and environmental applications. As photocatalysis bears a great potential for solar energy utilization, enormous investigations have been implemented in the past decades. The fundamental mechanism and some applications were well addressed in the last century. Currently, the major focus in photocatalysis research is the design and development of photocatalyst materials. This review firstly introduces the historic milestones in photocatalysis studies and then a comprehensive survey is conducted on the metal-based photocatalysts, including TiO2-based photocatalysts, ZnO and other metal oxides, metal sulfides, metal nitrides, and plasmon photocatalysts. From a historical viewpoint, particular attention is paid to metal-free graphitic carbon nitride (g-C3N4), a novel visible-light photocatalyst. Various modification techniques for g-C3N4 are summarized and analyzed. In terms of its metal-free nature, the fabrication of a porous structure, shape-control synthesis and non-metal doping are discussed in detail. Photocatalytic studies on g-C3N4-based catalysts are introduced. Some emerging elemental photocatalysts are also introduced. Finally, perspectives on non-metal photocatalyst design and development are provided. © 2016 The Royal Society of Chemistry

Pollution and Cleaning of PDMS Pervaporation Membranes after Recovering Ethyl Acetate from Aqueous Saline Solutions

The removal of volatile organic compounds (VOCs) from wastewater containing nonvolatile salts has become an important and interesting case of the application of the pervaporation (PV) process. The aim of this study was to evaluate the influence of salts on the PV removal of ethyl acetate from wastewater using a polydimethylsiloxane (PDMS) membrane. The fouled membrane was then characterized via scanning electron microscopy–energy-dispersive X-ray analysis (SEM–EDX) to investigate salt permeation. The membrane backflushing process was carried out by periodically flushing the permeate side of the tubular membrane. The results demonstrated that salts (NaCl and CaCl2) could permeate through the PDMS membrane and were deposited on the permeate side. The presence of salts in the feed solution caused a slight increase in the membrane selectivity and a decrease in the permeate flux. The flux decreased with increasing salt concentration, and a notable effect occurred at higher feed-salt concentrations. A permeate flux of up to 98.3% of the original flux was recovered when the permeation time and backflushing duration were 30 and 5 min, respectively, indicating that the effect of salt deposition on flux reduction could be mitigated. Real, organic, saline wastewater was treated in a pilot plant, which further verified the feasibility of wastewater PV treatment

The C-3 Functionalization of 1<i>H</i>-Indazole through Suzuki–Miyaura Cross-Coupling Catalyzed by a Ferrocene-Based Divalent Palladium Complex Immobilized over Ionic Liquid, as Well as Theoretical Insights into the Reaction Mechanism

The C-3 functionalization of 1H-indazole could produce a lot of highly valuable pharmaceutical precursors, which could be used for the treatment of cancer and many other inflammatory diseases. This work was focused on the C-3 functionalization of 1H-indazole through Suzuki–Miyaura cross-coupling of 3-iodo-1H-indazole with organoboronic acids, catalyzed by various palladium catalysts immobilized over imidazolium ionic liquids, as well as catalyst recycling. A series of reaction parameters, including the substrate, catalyst, and ionic liquid, were fully investigated. It is significant to note that the yields of the present Suzuki–Miyaura cross-coupling were mainly determined by the catalyst and the solvent used, more than the chemical structure of the substrate. Furthermore, ferrocene-based divalent palladium complexes showed better catalytic outputs compared to simple palladium salts. Moreover, using two imidazolium ionic liquids, BMImX (BMIm+ = 1-n-butyl-3-methylimidazolium, X− = BF4−, PF6−) not only improved the yields of cross-coupled products, but also avoided the formation of Pd(0) black, as compared to the non-ionic liquid facilitated reactions, and simultaneously making catalyst recycling more effective. On average, BMImBF4 performed better than BMImPF6. Additionally, scientific calculations revealed that 1,1′-bis(diphenylphosphino)ferrocene-palladium(II)dichloride dichloromethane complex (PdCl2(dppf)) showed a lower energy barrier in the formation of intermediates than [1,1′-bis(di-tert-butylphosphino)ferrocene]dichloropalladium(II) (PdCl2(dtbpf)), leading to higher catalytic outputs. This work may contribute to the development of 1H-indazole-derived new pharmaceuticals