An Introduction to the U.S. Municipal Bond Market

With a market value exceeding $2.6 trillion, the U.S. municipal securities market offers state and local governments many capital investment-financing opportunities. Many readers, however, may lack an understanding of the issuance process, the quality of the available information, or the inherent risks associated with these instruments. We describe the traditional municipal bonds process beginning with the initial offering preparations and the methods of sale. We discuss the types of interest costs and the use of the bond proceeds. We identify typical bond types and call provisions. We then turn to a discussion of the investment characteristics of municipal bonds. We explain credit ratings, credit enhancements, potential risks, and oversight and reporting. Our discussion is supplemented with data from the municipal bond market from 2001-2007. Our paper provides the reader with a basic understanding of the institutional structure, available information, and potential risks for this economically significant market

Keeping cool: Use of air conditioning by Australians with multiple sclerosis

Despite the known difficulties many people with MS have with high ambient temperatures, there are no reported studies of air conditioning use and MS. This study systematically examined air conditioner use by Australians with MS. A short survey was sent to all participants in the Australian MS Longitudinal Study cohort with a response rate of 76% (n=2,385). Questions included hours of air-conditioner use, areas cooled, type and age of equipment, and the personal effects of overheating. Air conditioners were used by 81.9% of respondents, with an additional 9.6% who could not afford an air conditioner. Regional and seasonal variation in air conditioning use was reported, with a national annual mean of 1,557 hours running time. 90.7% reported negative effects from overheating including increased fatigue, an increase in other MS symptoms, reduced household and social activities, and reduced work capacity. Households that include people with MS spend between 4 and 12 times more on keeping cool than average Australian households

In the Flower Crowned Green Mountains of Vermont

https://digitalcommons.library.umaine.edu/mmb-vp/6811/thumbnail.jp

A study of a five horse-power single phase induction motor

Thesis (B.S.)--University of Illinois, 1915.Typescript

Fees for Information Services to Hospitals: A California Experience

The project was directed toward planning, developing, and implementing a subregional biomedical information network among the forty-three health care facilities (hospitals) of the four-county area served by Loma Linda University\u27s health sciences library. The project coordinator contacted administrators and health care professionals in the forty-three institutions to present a plan for the network. The health care facilities were encouraged to support the continuation of the network through contract fees. The availability of specific information services was assured through contractual agreements. It was anticipated that the subregional network would be self-supporting after the twelve-month project period (December 1, 1976-November 30, 1977). The working territory (40,429 square miles) encompassed Mono, Inyo, Riverside, and San Bernardino counties. The project resulted in nine of the forty-three hospitals signing annual contracts for library services. It is recommended that projects of this kind extend beyond a year\u27s duration in order to educate health professionals concerning the value of access to biomedical literature in improving patient care

Empirical comparison of genotoxic potency estimations: the in vitro DNA-damage ToxTracker endpoints versus the in vivo micronucleus assay

Genetic toxicology is an essential component of compound safety assessment. In the face of a barrage of new compounds, higher throughput, less ethically divisive in vitro approaches capable of effective, human-relevant hazard identification and prioritisation are increasingly important. One such approach is the ToxTracker assay, which utilises murine stem cell lines equipped with green fluorescent protein (GFP)-reporter gene constructs that each inform on distinct aspects of cellular perturbation. Encouragingly, ToxTracker has shown improved sensitivity and specificity for the detection of known in vivo genotoxicants when compared to existing ‘standard battery’ in vitro tests. At the current time however, quantitative genotoxic potency correlations between ToxTracker and well-recognised in vivo tests are not yet available. Here we use dose–response data from the three DNA-damage-focused ToxTracker endpoints and from the in vivo micronucleus assay to carry out quantitative, genotoxic potency estimations for a range of aromatic amine and alkylating agents using the benchmark dose (BMD) approach. This strategy, using both the exponential and the Hill BMD model families, was found to produce robust, visually intuitive and similarly ordered genotoxic potency rankings for 17 compounds across the BSCL2-GFP, RTKN-GFP and BTG2-GFP ToxTracker endpoints. Eleven compounds were similarly assessed using data from the in vivo micronucleus assay. Cross-systems genotoxic potency correlations for the eight matched compounds demonstrated in vitro–in vivo correlation, albeit with marked scatter across compounds. No evidence for distinct differences in the sensitivity of the three ToxTracker endpoints was found. The presented analyses show that quantitative potency determinations from in vitro data enable more than just qualitative screening and hazard identification in genetic toxicology

Assistive Technology Pricingin Australia: Is It Efficient and Equitable?

Recently, concerns have been raised that in comparison to prices for assistive technology (AT) (e.g., disability aids and equipment)in other countries, Australian AT retailers’ prices are excessive. We present three sets of price comparisons for AT that indicate Australian prices arelow comparedto other countries. Further, there is no evidence of suppliers earning supranormal profits in Australia. Together, all the evidence suggests that AT prices in Australia are efficient and equitable. Efforts to reduce prices through the excessive use of large-scale government procurement programs are likely to reduce diversity and innovation in AT and raise AT prices over time