407 research outputs found

    Data protection, safeguarding and the protection of children's privacy: exploring local authority guidance on parental photography at school events

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    Should parents be allowed to take photographs at school events? Media reports suggest that increasingly schools are answering no to this question, either prohibiting or imposing stringent restrictions upon such photography. The legal justifications for such restrictions are, however, unclear. Accordingly, in 2013 freedom of information requests were sent to local education authorities across England, Scotland and Wales, the aim being to determine what advice local education authorities provide to schools in relation to parental photography at school events, and to identify how education authorities’ understandings of the law influence the advice they offer. That research reveals that local education authorities’ understandings of the law vary significantly and that where authorities do not fully appreciate the extent of the legal obligations arising this may have significant repercussions for the children concerned

    Assessment of knowledge and attitudes toward Complementary and Alternative Medicine (CAM) amongst Turkish medical faculty students

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    Background: Complementary and Alternative Medicine (CAM) therapies are becoming increasingly  acceptable to the general public and are increasingly used around the world. The international rise in focus  on CAM and the increased incorporation of CAM into medical curricula make it important to gain insight into the knowledge and attitudes of medical students about CAM and its integration in the medical curriculum.Materials and Methods: In this present study, we attempt to investigate the Cerrahpasa medical faculty students’ knowledge, attitude and practices of the students on CAM. The study used a primary  cross-sectional data collection from students of Cerrahpasa Medical Faculty, Istanbul University, in  2012-2013 academic years.Results: Students’ knowledge of CAM between classes was also compared. There were also statistically  significant differences about the knowledge of those methods (acupuncture, acupressure, yoga, reiki, prayer, meditation massage, dietary, spa). Prayer was the most known modality in all medical classes’ students (first year students: 254, sixth year students: 192). The students who participated in the study stated that 433 (%59.4) have some knowledge about the acupuncture (first year students: 229, sixth  year students: 204). Acupressure was found to be at least known methods for CAM (first year students:  313, sixth year students: 282).Conclusion: Medical students in our faculty had limited knowledge about CAM therapies. Medical  students also have an understanding of the importance of CAM education in the medical curriculum, specifically how it will positively influence professional attitude and stimulate the doctor–patient relationship.Key words: Medical, Students, Complementary and Alternative Medicine

    Adaptive Output Feedback Control of the NASA GTM Model with Unknown Nonminimum-Phase Zeros

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90722/1/AIAA-2011-6204-387.pd

    A dentigerous cyst associated with bilaterally impacted mandibular canines in a girl: a case report

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    Introduction: A dentigerous cyst is the most common developmental odontogenic cyst and is frequently noted as an incidental finding on radiographs. The most common teeth affected are impacted mandibular third molars and permanent maxillary canines. This case involves a dentigerous cyst encompassing the right and left impacted mandibular canines and crossing the midline. This is, to the best of our knowledge, the first reported case of a dentigerous cyst encompassing non-adjacent teeth and crossing the midline. Case presentation: The patient presented to our orthodontic clinic for treatment of malocclusion. The patient was a 10-year, one-month-old Caucasian girl with a dentigerous cyst encompassing the right and left impacted mandibular canines and crossing the midline. Conclusion: This case involves an unusual clinical and radiographic presentation of a dentigerous cyst. It shows a new variant of presentation that medical professionals, specifically dentists and radiologists, should be aware of, since a dentigerous cyst crossing the midline has not been previously reported as far as we are aware. This additional knowledge is important for inclusion on differential diagnosis lists and aids in the development of a proper treatment plan

    The effect of spacing on the vortex-induced vibrations of two tandem flexible cylinders

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    Vortex-induced vibrations (VIV) of two flexible cylinders arranged in tandem are studied using a two-way fluidstructure interaction (FSI) method with different spacing ratios (Sx/D) at Reynolds number Re = 500 using a twoway fluid-structure interaction (FSI) method. The main objective of this study is to investigate the effect of spacing on the hydrodynamic interactions and the VIV responses of these cylinders. The responses of the two flexible cylinders are found to be similar to the classical VIV responses at small Sx/D. Once Sx/D is large enough for the vortices to become detached from the upstream cylinder, the response of the upstream cylinder is similar to the typical VIV response whereas the downstream cylinder undergoes wake-induced vibration (WIV). The characteristics of the response of the downstream cylinder in the present study are similar to those of the first two response regimes classified by previous researchers. The third regime is not observed for the flexible downstream cylinder with both ends fixed. The two changes in the phase relation between the cross-flow displacements of the two tandem flexible cylinders are discovered to be linked with the initial-upper branch transition and the upperlower branch transition, respectively. The correlation lengths of the two flexible cylinders decrease significantly in the transition range between the upper and lower branches. Three modes of vortex shedding (2S, P + S and 2P) have been identified in the present study. The upper-branch 2P mode is found to be associated with largeamplitude vibration of the upstream cylinder and the P + S mode is observed to be related to large-amplitude vibration of the downstream cylinder for Sx/D = 3.5 and 5. On the other hand, the lower-branch 2P mode leads to small-amplitude vibration of the downstream cylinder in the post-lock-in range at Sx/D = 2.5. The relative phase shifts of the sectional lift coefficients on different spanwise cross sections can be attributed to the variation of the vortex shedding flow along the flexible cylinders, and these phase shifts result in poor phasing between the forces and the displacements which is related to the decrease of the correlation lengths

    Exploiting metabolic acidosis in solid cancers using a tumor-agnostic pH-activatable nanoprobe for fluorescence-guided surgery

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    Cancer cell metabolism leads to a uniquely acidic microenvironment in solid tumors, but exploiting the labile extracellular pH differences between cancer and normal tissues for clinical use has been challenging. Here we describe the clinical translation of ONM-100, a nanoparticle-based fluorescent imaging agent. This is comprised of an ultra-pH sensitive amphiphilic polymer, conjugated with indocyanine green, which rapidly and irreversibly dissociates to fluoresce in the acidic extracellular tumor microenvironment due to the mechanism of nanoscale macromolecular cooperativity. Primary outcomes were safety, pharmacokinetics and imaging feasilibity of ONM-100. Secondary outcomes were to determine a range of safe doses of ONM-100 for intra-operative imaging using commonly used fluorescence camera systems. In this study (Netherlands National Trial Register #7085), we report that ONM-100 was well tolerated, and four solid tumor types could be visualized both in- and ex vivo in thirty subjects. ONM-100 enables detection of tumor-positive resection margins in 9/9 subjects and four additional otherwise missed occult lesions. Consequently, this pH-activatable optical imaging agent may be clinically beneficial in differentiating previously unexploitable narrow physiologic differences

    The cBio cancer Genomics portal: An open platform for exploring multidimensional cancer genomics data

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    Cataloged from PDF version of article.The cBio Cancer Genomics Portal (http://cbioportal.org) is an open-access resource for interactive exploration of multidimensional cancer genomics data sets, currently providing access to data from more than 5,000 tumor samples from 20 cancer studies. The cBio Cancer Genomics Portal significantly lowers the barriers between complex genomic data and cancer researchers who want rapid, intuitive, and high-quality access to molecular profiles and clinical attributes from large-scale cancer genomics projects and empowers researchers to translate these rich data sets into biologic insights and clinical applications. © 2012 American Association for Cancer Research
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