863 research outputs found
PHP82 Impact of Clinical and Health Economic Publications on Commercial success of Pharmaceutical products in the U.S
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Actinide complexation kinetics: rate and mechanism of dioxoneptunium (V) reaction with chlorophosphonazo III
Rates of complex formation and dissociation in NpO{sub 2}{sup +}- Chlorophosphonazo III (2,7-bis(4-chloro-2-phosphonobenzeneazo)-1,8- dihydroxynapthalene-3,6-disulfonic acid)(CLIII) were investigated by stopped-flow spectrophotometry. Also, limited studies were made of the rates of reaction of La{sup 3+}, Eu{sup 3+}, Dy{sup 3+}, and Fe{sup 3+} with CLIII. Rate determining step in each system is an intramolecular process, the NpO{sub 2}{sup +}-CLIII reaction proceeding by a first order approach to equilibrium in the acid range from 0.1 to 1.0 M. Complex formation occurs independent of acidity, while both acid dependent and independent dissociation pathways are observed. Activation parameters for the complex formation reaction are {Delta}H=46.2{+-}0.3 kJ/m and {Delta}S=7{+-} J/mK (I=1.0 M); these for the acid dependent and independent dissociation pathways are {Delta}H=38.8{+-}0.6 kJ/m, {Delta}S=-96{+-}18 J/mK, {Delta}H=70.0{+-} kJ/m, and {Delta}S=17{+-}1 J/mK, respectively. An isokinetic relationship is observed between the activation parameters for CLIII complex formation with NpO{sub 2}{sup +}, UO{sub 2}{sup 2+}, Th{sup 4+}, and Zr{sup 4+}. Rates of CLIII complex formation reactions for Fe{sup 3+}, Zr{sup 4+}, NpO{sub 2}{sup +}, UO{sub 2}{sup 2+}, Th{sup 4+}, La{sup 3+}, Eu{sup 3+}, and Dy{sup 3+} correlate with cation radius rather than charge/radius ratio
Actinide Complexation Kinetics: Rate and Mechanism of Dioxoneptunium(V) Reaction with Chlorophosphonazo III
Rates of complex formation and dissociation in NpO{sub 2}{sup +}- Chlorophosphonazo III (2,7-bis(4-chloro-2-phosphonobenzeneazo)-1,8- dihydroxynapthalene-3,6-disulfonic acid)(CLIII) were investigated by stopped-flow spectrophotometry. Also, limited studies were made of the rates of reaction of La{sup 3+}, Eu{sup 3+}, Dy{sup 3+}, and Fe{sup 3+} with CLIII. Rate determining step in each system is an intramolecular process, the NpO{sub 2}{sup +}-CLIII reaction proceeding by a first order approach to equilibrium in the acid range from 0.1 to 1.0 M. Complex formation occurs independent of acidity, while both acid dependent and independent dissociation pathways are observed. Activation parameters for the complex formation reaction are {Delta}H=46.2{+-}0.3 kJ/m and {Delta}S=7{+-} J/mK (I=1.0 M); these for the acid dependent and independent dissociation pathways are {Delta}H=38.8{+-}0.6 kJ/m, {Delta}S=-96{+-}18 J/mK, {Delta}H=70.0{+-} kJ/m, and {Delta}S=17{+-}1 J/mK, respectively. An isokinetic relationship is observed between the activation parameters for CLIII complex formation with NpO{sub 2}{sup +}, UO{sub 2}{sup 2+}, Th{sup 4+}, and Zr{sup 4+}. Rates of CLIII complex formation reactions for Fe{sup 3+}, Zr{sup 4+}, NpO{sub 2}{sup +}, UO{sub 2}{sup 2+}, Th{sup 4+}, La{sup 3+}, Eu{sup 3+}, and Dy{sup 3+} correlate with cation radius rather than charge/radius ratio
Providing the Context for Intentional Learning
This article is written in response to Sharon Derry's article âRemediating Academic Difficulties Through Strategy Training: The Acquisition of Useful Knowledge.â The features of effective strategy instruction, to which Derry refers, are illustrated by examining the nature of the decisions the teacher confronts; specifically, determining the purposes of instruction, the context in which instruction occurs, and the roles of the teacher and students in instruction.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/69150/2/10.1177_074193259001100608.pd
The Mars Science Laboratory record of optical depth measurements via solar imaging
Acknowledgments We are grateful to the teams that developed, landed, and operated Curiosity on Mars, allowing for the present study. The research was conducted partly at the Jet Propulsion Laboratory, California Institute of Technology, under a contract with the National Aeronautics and Space Administration (80NM0018D0004). MTL was supported via sub-contract 18-1187 from Malin Space Science Systems, Inc. SDG was supported by the MSL Participating Scientist program. JMB was supported by MSL Participating Scientist Grant 80NSSC22K0657. AV-R was supported by the Comunidad de Madrid Project S2018/NMT-4291 (TEC2SPACE-CM). M-PZ was supported by grant PID2019-104205GB-C21 funded by MCIN/AEI/10.13039/501100011033. JM-T was supported by UK Space Agency projects ST/W00190X/1 and ST/V00610X/1.Peer reviewedPostprin
Running into New Territory in SUSY Parameter Space
The LEP-II bound on the light Higgs mass rules out the vast majority of
parameter space left to the Minimal Supersymmetric Standard Model (MSSM) with
weak-scale soft-masses. This suggests the importance of exploring extensions of
the MSSM with non-minimal Higgs physics. In this article, we explore a theory
with an additional singlet superfield and an extended gauge sector. The theory
has a number of novel features compared to both the MSSM and Next-to-MSSM,
including easily realizing a light CP-even Higgs mass consistent with LEP-II
limits, tan(beta) < 1, and a lightest Higgs which is charged. These features
are achieved while remaining consistent with perturbative unification and
without large stop-masses. Discovery modes at the Tevatron and LHC are
discussed.Comment: 15 pages, 5 figures; Typo in equation (4.5) corrected; submitted to
JHE
Measurements of 0.2 to 20 GeV/n cosmic-ray proton and helium spectra from 1997 through 2002 with the BESS spectrometer
We measured low energy cosmic-ray proton and helium spectra in the kinetic
energy range 0.215 - 21.5 GeV/n at different solar activities during a period
from 1997 to 2002. The observations were carried out with the BESS spectrometer
launched on a balloon at Lynn Lake, Canada. A calculation for the correction of
secondary particle backgrounds from the overlying atmosphere was improved by
using the measured spectra at small atmospheric depths ranging from 5 through
37 g/cm^2. The uncertainties including statistical and systematic errors of the
obtained spectra at the top of atmosphere are 5-7 % for protons and 6-9 % for
helium nuclei in the energy range 0.5 - 5 GeV/n.Comment: 27 pages, 7 Tables, 9 figures, Submitted to Astroparticle Physic
Effect of Docosahexaenoic Acid (DHA) Supplementation of Preterm Infants on Growth, Body Composition, and Blood Pressure at 7-Years Corrected Age: Follow-Up of a Randomized Controlled Trial
Aim: To determine if supplementation of infants born 0.1). High-DHA group infants were more likely to be classified as obese (relative risk 1.6 (95% CI 1.0, 2.6); p = 0.05). Conclusions: DHA supplementation of premature infants did not affect growth, body composition, or blood pressure at 7-year CA overall by sex and birthweight strata. The finding of a higher risk of obesity in children who receive high-DHA needs to be interpreted with caution due to the small number of children classified as obese.Karen P. Best, Thomas R. Sullivan, Anoja W. Gunaratne, Jacqueline F. Gould, Robert A. Gibson, Carmel T. Collins, Maria Makrides, and Tim J. Gree
Measurements of Proton, Helium and Muon Spectra at Small Atmospheric Depths with the BESS Spectrometer
The cosmic-ray proton, helium, and muon spectra at small atmospheric depths
of 4.5 -- 28 g/cm^2 were precisely measured during the slow descending period
of the BESS-2001 balloon flight. The variation of atmospheric secondary
particle fluxes as a function of atmospheric depth provides fundamental
information to study hadronic interactions of the primary cosmic rays with the
atmosphere.Comment: 21 pages, 11 figures, 4 table
Measurement of cosmic-ray low-energy antiproton spectrum with the first BESS-Polar Antarctic flight
The BESS-Polar spectrometer had its first successful balloon flight over
Antarctica in December 2004. During the 8.5-day long-duration flight, almost
0.9 billion events were recorded and 1,520 antiprotons were detected in the
energy range 0.1-4.2 GeV. In this paper, we report the antiproton spectrum
obtained, discuss the origin of cosmic-ray antiprotons, and use antiprotons to
probe the effect of charge sign dependent drift in the solar modulation.Comment: 18 pages, 1 table, 5 figures, submitted to Physics Letters
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