Colorectal carcinoma associated with schistosomiasis: a possible causal relationship

The association between schistosomiasis and colorectal malignancy has long been suggested in the literature, but it is not uniformly accepted. In the Far East, considerable evidence supports an etiological link between Schistosoma japonicum and colorectal cancer. However, the available data regarding the role of Schistosoma mansoni in colorectal carcinogenesis are conflicting and most often do not show causality. We report on a patient with sigmoid colonic cancer coexisting with schistosomiasis, and we provide a comprehensive review of the literature regarding the epidemiology and pathobiology of this association

Delay as a Challenge in Prosecuting Non-Compliance in the Halal Industry

This is aresearch identifying the causes and consequence of delay in prosecuting halal industry violation. In determining the reasons for the delay, the authors will look into firstly the procedure and process which shows non-uniformity of legal administration, secondly the scattered laws, policy, standards for the halal industry. The authors will refer to a reported local case law, making comparative study on previous legislation and the current one, to see the elaborated scope of law in relation to the courts decision as a result of delay

Evaluation of Road Pavement Maintenance by Contract in Jordan

In this research, road pavement maintenance by contract in Jordan was investigated. For this purpose, a subjective procedure (the Present Serviceability Rating (PSR)) was used to evaluate pavement serviceability. Three major highways (Jarash-Amman highway, Naour-Dead Sea highway and Zarqa-Syrian borders highway) that were maintained by contract were selected. The developed data base included information on pavement characteristics, traffic type and volume and routine maintenance cost. The effect of maintenance cost on pavement serviceability was estimated by developing a statistical relationship between maintenance cost and pavement serviceability rating before and after maintenance. The results showed that the pavement serviceability of Jarash-Amman highway and Naour-Dead Sea highway was adversely affected after applying maintenance by contract. The pavement serviceability of Zarqa-Syrian borders highway was slightly improved after applying maintenance by contract, but the improvement was not up to expectations. It is believed that the reasons for such results are a combination of the contractor’s poor experience and qualification and the timing of maintenance where the pavement was left without maintenance until it reached fair or poor condition

A Numerical Algorithm for Solving Stiff Ordinary Differential Equations

An advanced method using block backward differentiation formula (BBDF) is introduced with efficient strategy in choosing the step size and order of the method. Variable step and variable order block backward differentiation formula (VSVO-BBDF) approach is applied throughout the numerical computation.The stability regions of the VSVO-BBDFmethod are investigated and presented in distinct graphs.The improved performances in terms of accuracy and computation time are presented in the numerical results with different sets of test problems. Comparisons are made between the proposed method and MATLAB’s suite of ordinary differential equations (ODEs) solvers, namely, ode15s and ode23s

QSMSOR Iterative Method for the Solution of 2D Homogeneous Helmholtz Equations

In this paper, we consider the numerical solutions of homogeneous Helmholtz equations of the second order. The Quarter-Sweep Modified Successive Over-Relaxation (QSMSOR) iterative method is applied to solve linear systems generated form discretization of the second order homogeneous Helmholtz equations using quarter sweep finite difference (FD) scheme. The formulation and implementation of the method are also discussed. In addition, numerical results by solving several test problems are included and compared with the conventional iterative methods

Development of a Small Scale Okro Slicing Machine

The technique of slicing Okro using kitchen knife often exposes users to the danger of knife cut and the output of the technique has been found to be low due to the drudgery involved in the process. It was in recognition of the need to reduce drudgery, injury and associated rigors to the user and to enhance quality, hygiene and efficiency in Okro processing that the research of developing a suitable Okro slicing machine was initiated. A simple motorized device was developed for slicing okra using locally available materials which include: bearings, shaft, pulleys, electric motor, cutting blade, rail, bolts and nuts. The slicing mechanism was based on the high shear stress that is generated when a blade edge is brought into contact with fibrous material causing the blade to move in rotary motion and to the direction of the applied force. After coupling and testing the machine, results obtained showed that it takes 3 seconds to slice one Okro using machine while in the case of manual slicing, it takes 8.22 seconds. The device has a slicing efficiency of 66.67%.  The machine has shown to enhance processing of okra in small scale industry application. The machine therefore is of great importance to the industries within the country and beyond where preservation of Okro in sliced and dried form is important

Isolation and characterization of Pseudomonas aeruginosa and Brevibacillus species and their potential to biodegrade polyethylene material

This study was conducted to screen for Pseudomonas aeruginosa and Brevibacillus species from soil and investigate their ability to biodegrade low density polyethylene materials. The organisms were isolated using phenotypic characterization and molecular identification by polymerase chain reaction (PCR). The PCR confirmed the presence of two different strains of Pseudomonas aeruginosa and absence of Brevibacillus specie from the soil sample. The bacteria were inoculated in a nutrient broth to which 2% polyethylene was amended for a period of three weeks in a shaker incubator at 180rpm. Effect of temperature, pH and concentration of polyethylene on the biodegradation process was also studied. The initial and final dry weights of the polyethylene were recorded and the % degraded was calculated. It was found that both strains of Pseudomonas aeruginosa were capable of degrading the polyethylene. Strain C3 produced a maximum degradation of 20% at 37°C and pH 6. Strain B3 achieved a maximum degradation of 15% at 37°C at pH 6 and 7. In addition, it was found that both strains of Pseudomonas aeruginosa were able to survive up to 6% of polyethylene producing a maximum degradation of 55%. Therefore strains B3 and C3 of Pseudomonas aeruginosa can be effective in biodegradation of polyethylene in dump sites if their potentials are well exploited

Optimized hybrid methods for solving oscillatory second order initial value problems

Two-step optimized hybrid methods of order five and order six are developed for the integration of second order oscillatory initial value problems. The optimized hybrid method (OHMs) are based on the existing nonzero dissipative hybrid methods. Phase-lag, dissipation or amplification error, and the differentiation of the phase-lag relations are required to obtain the methods. Phase-fitted methods based on the same nonzero dissipative hybrid methods are also constructed. Numerical results show that OHMs are more accurate compared to the phase-fitted methods and some well-known methods appeared in the scientific literature in solving oscillating second order initial value problems. It is also found that the nonzero dissipative hybrid methods are more suitable to be optimized than phase-fitted methods

Spread of imipenem-resistant Acinetobacter baumannii co-expressing OXA-23 and GES-11 carbapenemases in Lebanon

© 2015 The Authors. Objectives: The acquisition of carbapenemases by Acinetobacter baumannii is reported increasingly worldwide, but data from Lebanon are limited. The aims of this study were to evaluate the prevalence of imipenem-resistant A. baumannii in Lebanon, identify resistance determinants, and detect clonal relatedness. Methods: Imipenem-resistant A. baumannii were collected from nine Lebanese hospitals during 2012. Antimicrobial susceptibility, the cloxacillin effect, and ethylenediaminetetraacetic acid (EDTA) synergy were determined. Genes encoding carbapenemases and insertion sequence IS. Aba1 were screened via PCR sequencing. IS. Aba1 position relative to genes encoding Acinetobacter-derived cephalosporinases (ADCs) and OXA-23 was studied by PCR mapping. Clonal linkage was examined by enterobacterial repetitive intergenic consensus PCR (ERIC-PCR). Results: Out of 724 A. baumannii isolated in 2012, 638 (88%) were imipenem-resistant. Of these, 142 were analyzed. Clavulanic acid-imipenem synergy suggested carbapenem-hydrolyzing extended-spectrum β-lactamase. A positive cloxacillin test indicated ADCs, while EDTA detection strips were negative. Genotyping indicated that 90% of isolates co-harbored blaOXA-23 and blaGES-11. The remaining strains had blaOXA-23, blaOXA-24, blaGES-11, or blaOXA-24 with blaGES-11. ISAba1 was located upstream of blaADC and blaOXA-23 in 97% and 100% of isolates, respectively. ERIC-PCR fingerprinting revealed 18 pulsotypes spread via horizontal gene transfer and clonal dissemination. Conclusion: This survey established baseline evidence of OXA-23 and GES-11-producing A. baumannii in Lebanon, indicating the need for further surveillance

Propofol cardioplegia: A single-center, placebo-controlled, randomized controlled trial

OBJECTIVES: Cardiac surgery with cardiopulmonary bypass and cardioplegic arrest is an effective treatment for coronary artery and aortic valve diseases. However, the myocardium sustains reperfusion injury after ischemic cardioplegic arrest. Our objective was to assess the benefits of supplementing cardioplegia solution with the general anesthetic propofol in patients undergoing either coronary artery bypass grafting (CABG) or aortic valve replacement (AVR). METHODS: A single-center, double-blind randomized controlled trial was carried out to compare cardioplegia solution supplemented with propofol (concentration 6 μg/mL) versus intralipid (placebo). The primary outcome was cardiac troponin T release over the first 48 hours after surgery. RESULTS: We recruited 101 participants (51 in the propofol group, 50 in the intralipid group); 61 underwent CABG and 40 underwent AVR. All participants were followed to 3 months. Cardiac troponin T release was on average 15% lower with propofol supplementation (geometric mean ratio, 0.85; 95% confidence interval [CI], 0.73-1.01; P = .051). There were no differences for CABG participants but propofol-supplemented participants undergoing AVR had poorer postoperative renal function (geometric mean ratio, 1.071; 95% CI, 1.019-1.125; P = .007), with a trend toward longer intensive care stay (median, 89.5 vs 47.0 hours; hazard ratio, 0.58; 95% CI, 0.31-1.09; P = .09) and fewer with perfect health (based on the EQ-5D health utility index) at 3 months (odds ratio, 0.26; 95% CI, 0.06-1.05; P = .058) compared with the intralipid group. Safety profiles were similar. There were no deaths. CONCLUSIONS: Propofol supplementation in cardioplegia appears to be cardioprotective. Its influence on early clinical outcomes may differ between CABG and AVR surgery. A larger, multicenter study is needed to confirm or refute these suggestions