4 research outputs found

    Computational Intelligence and Cerebellar Enigmas

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    A three-layer cerebellar cortex presents a kind of ideal network for early perceptron theories, but its functioning is much more complicated. Three related topics connected with information coding and memorizing mechanisms in the cerebellum are considered: 1) demonstration that activity transformation by granule cells, conserves the signal continuity provided by snake-in-box type codes; 2) determining precision requirements for the standard CMAC as well as for more realistic cerebellar models to meet demands of adaptive critic based solutions for a nonlinear control problem (swinging pendulum); and 3) demonstration that the closed loop scheme for the synaptic weight adjustment provides a precise setting of cerebellar input-output relations and multiple predictions for physiological experiments

    Comparison of ixekizumab with etanercept or placebo in moderate-to-severe psoriasis (UNCOVER-2 and UNCOVER-3): results from two phase 3 randomised trials.

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