12 research outputs found

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    Not AvailableThermal processing is the most efficient and economical technique for the long-term preservation of tender jackfruit in ready-to-cook form on a commercial-scale. Although, thermal processing primarily focus on microbiological safety of the product, the associated quality changes need to be examined as it is decisive of consumer acceptance. The present study investigated the effect of two pasteurization (90 and 100 °C) and sterilization temperatures (110 and 121 °C) at different lethality on microbiological, colour, texture, ascorbic acid (AA), total flavonoid (TFC) and phenol (TPC) contents of tender jackfruit processed in tin-free-steel (TFS) cans. Time required for thermal processing was computed from respective heat penetration curve. Thermal processing improved both the TFC and TPC of tender jackfruit, while colour, texture and AA had degraded. Based on microbiological and physicochemical quality analyses, the study adjudged pasteurization at 90 °C for 19 min and sterilization at 121 °C for 8 min as the best temperature–time combination for thermal processing of tender jackfruit in TFS cans.Not Availabl

    Completeness of low anterior resection pathology report: A hospital-based audit with recommendations on improving reporting

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    Aims: To audit the information content of the pathology report on Low Anterior Resection (LAR) specimens and to provide recommendations in order to improve the existing standard of reporting. Materials and Methods : All the reports of LAR specimens during 2004 - 2005 were collected from the Hospital Information System (HIS). Individual items of information were compared with the minimum data sets provided by the Royal College of Pathologists (RCP). Results : Fifty-nine reports were audited. Nineteen percent of the reports were classified as satisfactory. Although many items were well reported, only 30.5% (18/59) of the reports contained a statement on the completeness of excision at the circumferential resected margin and only 25.4% of all reports mentioned the relation of tumors to the peritoneal reflection. Conclusion : The information content of the reports on colorectal cancer resection specimens is inadequate. The use of the standard proforma (template) for reporting rectal cancer is therefore recommended, along with improved education, review of laboratory practices in the light of current knowledge, and further motivation of pathologists through their involvement in multidisciplinary cancer management

    Completeness of low anterior resection pathology report: A hospital-based audit with recommendations on improving reporting

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    Aims: To audit the information content of the pathology report on Low Anterior Resection (LAR) specimens and to provide recommendations in order to improve the existing standard of reporting. Materials and Methods : All the reports of LAR specimens during 2004 - 2005 were collected from the Hospital Information System (HIS). Individual items of information were compared with the minimum data sets provided by the Royal College of Pathologists (RCP). Results : Fifty-nine reports were audited. Nineteen percent of the reports were classified as satisfactory. Although many items were well reported, only 30.5% (18/59) of the reports contained a statement on the completeness of excision at the circumferential resected margin and only 25.4% of all reports mentioned the relation of tumors to the peritoneal reflection. Conclusion : The information content of the reports on colorectal cancer resection specimens is inadequate. The use of the standard proforma (template) for reporting rectal cancer is therefore recommended, along with improved education, review of laboratory practices in the light of current knowledge, and further motivation of pathologists through their involvement in multidisciplinary cancer management

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    Not AvailableVelvet bean is an important underutilized medicinal plant widely used in traditional system of medicine. Its seed are rich in protein, minerals and as a major source of biomolecule L-Dopa, which is used for the treatment of Parkinson’s disease. Seeds of six parents and 15 hybrids resulting from half-diallel design excluding reciprocals were analysed for various biochemical traits such as L-Dopa, total phenols, total tannins, crude protein and fat. The sca variance was greater than gca variance for biochemical traits. This indicated that the predominance of non-additive gene action governing the inheritance of these characters. The present study identified hybrids IIHR Selection 2 × Arka Aswini, Arka Aswini × IIHR Selection LP, Arka Dhanvantari × Arka Aswini, Arka Dhanvantari × IIHR Selection 3 with high average heterosis and heterobeltiosis for L-Dopa, total phenols and total tannins. The crosses IIHR Selection 3 × IIHR Selection LP and IIHR Selection 2 × IIHR Selection LP have manifested high heterosis over mid parent and better parent for protein. IIHR Selection 2 was a good general combiner for high L-Dopa and total phenolics. Arka Aswinini was identified as best general combiner for total tannin. Arka Dhanvantari and IIHR Selection 3 were found to be good general combiners for protein and fat. The Hybrids Arka Dhanvantari × Arka Aswini and IIHR Selection 2 × Arka Aswini were best cross combiners for high L-Dopa for pharmaceutical use and Arka Dhanvantari × IIHR Selection 2 for low L-Dopa for food and feed purpose. The cross IIHR Selection 3 × IIHR Selection LP was best specific cross combiner for protein content, which could be used in the future breeding programme of velvet bean.Not Availabl

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    Not AvailableMucuna pruriens(L.) is an important underutilized legume medicinal plant. It is an herbaceous annual twiningclimber. Its seeds are used to extract the L-Dopa (L-3, 4-dihydroxyphenylalanine) to the preparation of the drugsand are used in the treatment of Parkinson’s disease. Mucuna seeds are rich source of L-Dopa in addition toprotein and other minerals. In the present study estimation of L-Dopa and other biochemical traits in 58 gen-otypes of velvet bean has been analyzed to identify the genotypes having maximum seed yield coupled with highL-Dopa to the preparation of drugs. The L-Dopa is varied significantly from 2.94 to 6.91% among mucunagenotypes. The levels of total phenol content and tannins varied significantly among genotypes and ranged from27.73 to 103.50 mg/100 g and 0.18 to 0.96 mg/100 g DW, respectively. The protein content in the estimatedgenotypes of Mucuna seed greatly varied from 19.08% to 38.18% with a mean value of 28.16%. Significantlymaximum L-Dopa, total phenol content, total tannin, crude protein, fat and carbohydrate was recorded in IIHRMP 62-1 (6.91%), IIHR MP 62-2 (103.50 mg/100 g), IIHR MP 63-1 (0.96 mg/100 g), IIHR MP-74 (38.18%), IIHRMP 95 (7.54%) and IIHR MP 62-3 (64.36%), respectively. Significantly low L-Dopa, total phenol content, totaltannin found in IC 332432 (2.94%), IIHR MP 89-1 (27.73 mg/100 g), IIHR MP 10 (0.183 mg/100 g), respec-tively. Biochemical traits viz., crude protein, fat and carbohydrate found less in EC 17827 (19.08%), IIHR MP 62-3 (3.10%) and IIHR MP 74 (47.81%), respectively. Cluster analysis based on biochemical data revealed that thecluster I showed highest mean value for L-Dopa and total phenol content, cluster III for total tannin and clusterVI for crude protein. The results showed that intra cluster distance was maximum in cluster VI (167.51) andmaximum inter cluster distance was between cluster I and V (2014.94). Total phenol content was the maincontributor to the total genetic divergence. The traits fat and L-Dopa were moderately contributing and car-bohydrate was least contributing to the total divergence of the estimated biochemical traits. The genotypesbelonging to the cluster with maximum inter cluster distance are genetically more divergent and these genotypescould be used in the hybridization programme of velvet bean to evolve high L-Dopa type to meet the demand of drug industry.Not Availabl

    Barriers to rehabilitation after critical illness: a survey of multidisciplinary healthcare professionals caring for ICU survivors in an acute care hospital

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    Background: There is scant literature on the barriers to rehabilitation for patients discharged from the intensive care unit (ICU) to acute care wards. Objectives: The objective of this study was to assess ward-based rehabilitation practices and barriers and assess knowledge and perceptions of ward clinicians regarding health concerns of ICU survivors. Methods, design, setting, and participants: This was a single-centre survey of multidisciplinary healthcare professionals caring for ICU survivors in an Australian tertiary teaching hospital. Main outcome measures: The main outcome measures were knowledge of post-intensive care syndrome (PICS) amongst ward clinicians, perceptions of ongoing health concerns with current rehabilitation practices, and barriers to inpatient rehabilitation for ICU survivors. Results: The overall survey response rate was 35% (198/573 potential staff). Most respondents (66%, 126/ 190) were unfamiliar with the term PICS. A majority of the respondents perceived new-onset physical weakness, sleep disturbances, and delirium as common health concerns amongst ICU survivors on acute care wards. There were multifaceted barriers to patient mobilisation, with inadequate multidisciplinary staffing, lack of medical order for mobilisation, and inadequate physical space near the bed as common institutional barriers and patient frailty and cardiovascular instability as the commonly perceived patient-related barriers. A majority of the surveyed ward clinicians (66%, 115/173) would value education on health concerns of ICU survivors to provide better patient care. Conclusion: There are multiple potentially modifiable barriers to the ongoing rehabilitation of ICU survivors in an acute care hospital. Addressing these barriers may have benefits for the ongoing care of ICU survivors

    Barriers to rehabilitation after critical illness:A survey of multidisciplinary healthcare professionals caring for ICU survivors in an acute care hospital

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    Background There is scant literature on the barriers to rehabilitation for patients discharged from the intensive care unit (ICU) to acute care wards. Objectives The objective of this study was to assess ward-based rehabilitation practices and barriers and assess knowledge and perceptions of ward clinicians regarding health concerns of ICU survivors. Methods, design, setting, and participants This was a single-centre survey of multidisciplinary healthcare professionals caring for ICU survivors in an Australian tertiary teaching hospital. Main outcome measures The main outcome measures were knowledge of post–intensive care syndrome (PICS) amongst ward clinicians, perceptions of ongoing health concerns with current rehabilitation practices, and barriers to inpatient rehabilitation for ICU survivors. Results The overall survey response rate was 35% (198/573 potential staff). Most respondents (66%, 126/190) were unfamiliar with the term PICS. A majority of the respondents perceived new-onset physical weakness, sleep disturbances, and delirium as common health concerns amongst ICU survivors on acute care wards. There were multifaceted barriers to patient mobilisation, with inadequate multidisciplinary staffing, lack of medical order for mobilisation, and inadequate physical space near the bed as common institutional barriers and patient frailty and cardiovascular instability as the commonly perceived patient-related barriers. A majority of the surveyed ward clinicians (66%, 115/173) would value education on health concerns of ICU survivors to provide better patient care. Conclusion There are multiple potentially modifiable barriers to the ongoing rehabilitation of ICU survivors in an acute care hospital. Addressing these barriers may have benefits for the ongoing care of ICU survivors

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    Not AvailableVelvet bean is an important medicinal legume, its seeds are prominent source of L-Dopa. The present investigation on genetic diversity assessment of 58 germplasm of velvet bean by using 11 ISSR markers. Out of 63 amplified products 59 were showed polymorphism and 4 were monomorphic with an average of 5.7 bands amplified per primer. According to band statistics and efficiency parameters showed the primers UBC 827, UBC 834 and UBC 836 were more efficient. The highest genetic similarity values (0.90) were observed between IIHR MP 102 and IIHR MP 74-3. In dendrogram germplasm grouped into two major clusters at 63 per cent similarity. Among the germplasm, IIHR Selection 4, IIHR Selection 10, IIHR MP 9, IC 33243 and IIHR MP 7 were found to be distinctly divergent, can be used in the further breeding programme.Not Availabl
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