Microscopic study of neutrino trapping in hyperon stars

Employing the most recent parametrization of the baryon-baryon interaction of the Nijmegen group, we investigate, in the framework of the Brueckner--Bethe--Goldstone many-body theory at zero temperature, the influence of neutrino trapping on the composition, equation of state, and structure of neutron stars, relevant to describe the physical conditions of a neutron star immediately after birth (protoneutron star). We find that the presence of neutrinos changes significantly the composition of matter delaying the appearance of hyperons and making the equation of state stiffer. We explore the consequences of neutrino trapping on the early evolution of a neutron star and on the nature of the final compact remnant left by the supernova explosion.Comment: Astronomy & Astrophysics, 399, 687-693 (2003

HLA-G: expression in human keratinocytes in vitro and in human skin in vivo

Classical, polymorphic major histocompatibility complex class I molecules are expressed on most nucleated cells.They present peptides at the cell surface and, thus, enable the immune system to scan peptides for their antigenicity. The function of the other, nonclassical class I molecules in man is controversial. HLA-G which has been shown by transfection experiments to be expressed at the cell surface, is only transcribed in placental tissue and in the fetal eye.Therefore, a role of HLA-G in the control of rejection of the allogeneic fetus has been discussed. We found that HLA-G expression is induced in keratinocytes by culture in vitro. Three different alternative splicing products of HLA-G can be detected: a full length transcript, an mRNA lacking exon 3 and a transcript devoid of exon 3 and 4. Reverse transcription followed by polymerase chain reaction also revealed the presence of HLA-G mRNA in vivo in biopsies of either diseased or healthy skin

IRFM T_eff calibrations for cluster and field giants in the Vilnius, Geneva, RI(C) and DDO photometric systems

Based on a large sample of disk and halo giant stars, for which accurate effective temperatures derived through the InfraRed Flux Method (IRFM) exist, a calibration of the temperature scale in the Vilnius, Geneva, RI(C) and DDO photometric systems is performed. We provide calibration formulae for the metallicity dependent T_eff vs color relations as well as grids of intrinsic colors and compare them with other calibrations. Photometry, atmospheric parameters and reddening corrections for the stars of the sample have been updated with respect to the original sources in order to reduce the dispersion of the fits. Application of our results to Arcturus leads to an effective temperature in excellent agreement with the value derived from its angular diameter and integrated flux. The effects of gravity on these T_eff vs color relations are also explored by taking into account our previous results for dwarf stars.Comment: Accepted for publication in A&

A List of Bright Interferometric Calibrators measured at the ESO VLTI

In a previous publication (Richichi & Percheron 2005) we described a program of observations of candidate calibrator stars at the ESO Very Large Telescope Interferometer (VLTI), and presented the main results from a statistical point of view. In the present paper, we concentrate on establishing a new homogeneous group of bright interferometric calibrators, based entirely on publicly available K-band VLTI observations carried out with the VINCI instrument up to July 2004. For this, we have defined a number of selection criteria for the quality and volume of the observations, and we have accordingly selected a list of 17 primary and 47 secondary calibrators. We have developed an approach to a robust global fit for the angular diameters using the whole volume of quality-controlled data, largely independent of a priori assumptions. Our results have been compared with direct measurements, and indirect estimates based on spectrophotometric methods, and general agreement is found within the combined uncertainties. The stars in our list cover the range K=-2.9 to +3.0 mag in brightness, and 1.3 to 20.5 milliarcseconds in uniform-disk diameter. The relative accuracy of the angular diameter values is on average 0.4% and 2% for the primary and secondary calibrators respectively. Our calibrators are well suited for interferometric observations in the near-infrared on baselines between ~20m and ~200m, and their accuracy is superior, at least for the primary calibrators, to other similar catalogues. Therefore, the present list of calibrators has the potential to lead to significantly improved interferometric scientific results

First High Contrast Imaging Using a Gaussian Aperture Pupil Mask

Placing a pupil mask with a gaussian aperture into the optical train of current telescopes represents a way to attain high contrast imaging that potentially improves contrast by orders of magnitude compared to current techniques. We present here the first observations ever using a gaussian aperture pupil mask (GAPM) on the Penn State near-IR Imager and Spectrograph (PIRIS) at the Mt. Wilson 100$^{\prime\prime}$ telescope. Two nearby stars were observed, $\epsilon$ Eridani and $\mu$ Her A. A faint companion was detected around $\mu$ Her A, confirming it as a proper motion companion. Furthermore, the observed H and K magnitudes of the companion were used to constrain its nature. No companions or faint structure were observed for $\epsilon$ Eridani. We found that our observations with the GAPM achieved contrast levels similar to our coronographic images, without blocking light from the central star. The mask's performance also nearly reached sensitivities reported for other ground based adaptive optics coronographs and deep HST images, but did not reach theoretically predicted contrast levels. We outline ways that could improve the performance of the GAPM by an order of magnitude or more.Comment: 8 pages, 4 figures, accepted by ApJ letter

Developing, delivering and documenting rehabilitation in a multi-centre randomised controlled surgical trial: experiences from the ProFHER trial

OBJECTIVES: A rigorous approach to developing, delivering and documenting rehabilitation within randomised controlled trials of surgical interventions is required to underpin the generation of reliable and usable evidence. This article describes the key processes used to ensure provision of good quality and comparable rehabilitation to all participants of a multi-centre randomised controlled trial comparing surgery with conservative treatment of proximal humeral fractures in adults. METHODS: These processes included the development of a patient information leaflet on self-care during sling immobilisation, the development of a basic treatment physiotherapy protocol that received input and endorsement by specialist physiotherapists providing patient care, and establishing an expectation for the provision of home exercises. Specially designed forms were also developed to facilitate reliable reporting of the physiotherapy care that patients received. RESULTS: All three initiatives were successfully implemented, alongside the measures to optimise the documentation of physiotherapy. Thus, all participating sites that recruited patients provided the sling immobilisation leaflet, all adhered to the physiotherapy protocol and all provided home exercises. There was exemplary completion of the physiotherapy forms that often reflected a complex patient care pathway. These data demonstrated equal and high access to and implementation of physiotherapy between groups, including the performance of home exercises. CONCLUSION: In order to increase the validity and relevance of the evidence from trials of surgical interventions and meet international reporting standards, careful attention to study design, conduct and reporting of the intrinsic rehabilitation components is required. The involvement of rehabilitation specialists is crucial to achieving this. Cite this article: Bone Joint Res 2014;3:335–40

An uncharged amine in the transition state of the ribosornal peptidyl transfer reaction.

The ribosome has an active site comprised of RNA that catalyzes peptide bond formation. To understand how RNA promotes this reaction requires a detailed understanding of the chemical transition state. Here, we report the Bronsted coefficient of the a-amino nucleophile with a series of puromycin derivatives. Both 50S subunit- and 70S ribosome-catalyzed reactions displayed linear free-energy relationships with slopes close to zero under conditions where chemistry is rate limiting. These results indicate that, at the transition state, the nucleophile is neutral in the ribosome-catalyzed reaction, in contrast to the substantial positive charge reported for typical uncatalyzed aminolysis reactions. This suggests that the ribosomal transition state involves deprotonation to a degree commensurate with nitrogen-carbon bond formation. Such a transition state is significantly different from that of uncatalyzed aminolysis reactions in solution

The Age Of Globular Clusters In Light Of Hipparcos: Resolving the Age Problem?

We review five independent techniques which are used to set the distance scale to globular clusters, including subdwarf main sequence fitting utilizing the recent Hipparcos parallax catalogue. These data together all indicate that globular clusters are farther away than previously believed, implying a reduction in age estimates. This new distance scale estimate is combined with a detailed numerical Monte Carlo study designed to assess the uncertainty associated with the theoretical age-turnoff luminosity relationship in order to estimate both the absolute age and uncertainty in age of the oldest globular clusters. Our best estimate for the mean age of the oldest globular clusters is now $11.5\pm 1.3$Gyr, with a one-sided, 95% confidence level lower limit of 9.5 Gyr. This represents a systematic shift of over 2 $\sigma$ compared to our earlier estimate, due completely to the new distance scale---which we emphasize is not just due to the Hipparcos data. This now provides a lower limit on the age of the universe which is consistent with either an open universe, or a flat, matter dominated universe (the latter requiring H_0 \le 67 \kmsmpc). Our new study also explicitly quantifies how remaining uncertainties in the distance scale and stellar evolution models translate into uncertainties in the derived globular cluster ages. Simple formulae are provided which can be used to update our age estimate as improved determinations for various quantities become available.Comment: 41 pages, including 10 eps figs, uses aaspp4.sty and flushrt.sty, submitted to Ap.J., revised to incorporate FULL Hipparcos catalogue dat

Thermodynamic phase diagram of Fe(Se0.5Te0.5) single crystals in fields up to 28 tesla

International audienceWe report on specific heat Cp , transport, Hall probe, and penetration depth measurements performed on Fe Se0.5Te0.5 single crystals Tc 14 K . The thermodynamic upper critical field Hc2 lines has been deduced from Cp measurements up to 28 T for both H c and H ab, and compared to the lines deduced from transport measurements up to 55 T in pulsed magnetic fields . We show that this thermodynamic Hc2 line presents a very strong downward curvature for T→Tc which is not visible in transport measurements. This temperature dependence associated to an upward curvature of the field dependence of the Sommerfeld coefficient confirms that Hc2 is limited by paramagnetic effects. Surprisingly this paramagnetic limit is visible here up to T/Tc 0.99 for H ab which is the consequence of a very small value of the coherence length c 0 4 Å and ab 0 15 Å , confirming the strong renormalization of the effective mass as compared to DMFT calculations previously observed in ARPES measurements A. Tamai, A. Y. Ganin, E. Rozbicki, J. Bacsa, W. Meevasana, P. D. C. King, M. Caffio, R. Schaub, S. Margadonna, K. Prassides, M. J. Rosseinsky, and F. Baumberger, Phys. Rev. Lett. 104, 097002 2010 . Hc1 measurements lead to ab 0 =430 50 nm and c 0 =1600 200 nm and the corresponding anisotropy is approximatively temperature independent 4 , being close to the anisotropy of Hc2 for T→Tc. The temperature dependence of both T2 and the electronic contribution to the specific heat confirm the nonconventional coupling mechanism in this system