16 research outputs found
Antimicrobial Potential of Momordica charantia L. against Multiresistant Standard Species and Clinical Isolates
- Author
- Alam S Asad M, Asdaq SM, Prasad VS.
- Aligiannis N Kalpotzakis E, Mitaku S, Chinou IB.
- Alves EG et al.
- Andews JM.
- Assubaie NF El-Garawany MM.
- Cakici I et al.
- Chunthorng-Orn J Panthong S, Itharat A.
- Dora CL Souza LC.
- Dropa M et al.
- Esebelahie NO Enweani IB, Omoregie R.
- Foa-Tomasi L Campadelli-Fiume G, Barbieri L, Stirpe F.
- França EL et al.
- Gales AC Menezes LC, Silbert S, Sader HS.
- Gehrke IT et al.
- Gelatti LC Bonamigo RR, Becker AP, D'Azevedo PA.
- Gobbo-Neto L Lopes NP.
- Grover JK Yadav SP.
- Hsiao PC et al.
- Koch CR et al.
- Krishnan PA.
- Lu KH et al.
- Moreira RCT Costa LCB, Costa RCS, Rocha EA.
- Nirmala MJ Mukherjee A, Chandrasekaran N.
- Omoregbe RE Ikuebe OM, Ihimire IG.
- Pasqualotto AC Nedel WL, Machado TS, Severo LC.
- Pasqualotto AC Nedel WL, Machado TS, Severo LC.
- Paul M et al.
- Pongthanapisith V Ikuta K, Puthavathana P, Leelamanit W.
- Pál S et al.
- Pérez ALAL et al.
- Raman A Lau C.
- Ranario JC Reddick CS, Peterson JD, Smith JL.
- Rodríguez-Banõ J et al.
- Sader HS Reis AO, Silbert S, Gales AC.
- Santos KK et al.
- Sardi JCO et al.
- Sena MF et al.
- Singh D Kumar TR, Gupt VK, Chaturvedi P.
- Stickler DJ Jones GL.
- Stover CK et al.
- Stramandinoli RT et al.
- Yesilada E Gurbuz I, Shibata H.
- Yuwai KE et al.
- Zheng YT Bem KL, Jin SW.
- Publication venue
- 'Jaypee Brothers Medical Publishing'
- Publication date
- Field of study
An interbacterial toxin inhibits target cell growth by synthesizing (p)ppApp
- Author
- A Rietsch
- A Stamatakis
- AB Russell
- AG Wexler
- AJ Stevens
- AL Goodman
- Alexei Savchenko
- Andrew G. McArthur
- AO Gaca
- B Wang
- Boyuan Wang
- C Camacho
- CK Stover
- CR Raetz
- D Hyatt
- D Quentin
- DG Lee
- E Sarubbi
- ET Granato
- G Bunkóczi
- GC Atkinson
- GL Winsor
- Hiu-Ki R. Tran
- HJ Rhaese
- HJ Rhaese
- J Beljantseva
- JC Whitney
- JC Whitney
- JN Marden
- John C. Whitney
- K Potrykus
- KD LaCourse
- KE McGinness
- LR Hmelo
- LS Johnson
- Matthew D. Walker
- MC Manav
- Michael T. Laub
- P Emsley
- PD Adams
- Peter J. Stogios
- RD Hood
- Robert A. Grant
- Shehryar Ahmad
- TD Bugg
- TJ Treangen
- V Hauryliuk
- W Kabsch
- W Minor
- W Steinchen
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Ribonucleotide reductase and cancer: biological mechanisms and targeted therapies
- Author
- A Bourdon
- A Chabes
- A Chabes
- A Cohen
- A Gautam
- A Gautam
- A Graslund
- A Hofer
- A Popovic-Bijelic
- A Saada
- A Sandler
- A Saven
- A Shaibani
- AC Bester
- AG Lu
- AL Chabes
- AL Chabes
- AM Bergman
- AR Fersht
- B Ullman
- BA Kunz
- BB Zhou
- C Manegold
- C Rampazzo
- C Reynolds
- C Temperini
- CK Mathews
- CL Jorgensen
- CM Hu
- CM Nutting
- D Ahluwalia
- D Chandra
- D Filatov
- D Reischl
- DD Anderson
- DI Feig
- DS Sigal
- E Johansson
- E Mansson
- EC Minnihan
- ET Lis
- FW Perrino
- G Bepler
- G Bepler
- G Bepler
- G Ferrandina
- G Kollberg
- G Nocentini
- G Pontarin
- G Pontarin
- G Pontarin
- G Simon
- G Weinberg
- GA McClarty
- H Akita
- H Fan
- H Fan
- H Fan
- H Gonzalez
- H Mandel
- H Niida
- H Okumura
- H Okumura
- H Tanaka
- H Tang
- H Tyynismaa
- H Uramoto
- HL Elford
- IW Caras
- J Moss
- J Petruska
- J Pfisterer
- J Rodriguez
- J Shao
- J Sigmond
- J Stubbe
- J Stubbe
- J Wang
- JA Cotruvo
- JA Wright
- JD Davidson
- JG Cory
- JW Fairman
- K Bebenek
- K Chimploy
- K Nakano
- K Ohtaka
- K Zhang
- KM Aird
- KM Aird
- KM King
- KR Martin
- L Akerblom
- L Chang
- L Xue
- L Zhu
- LJ Wheeler
- LM Alvarez-Salas
- LM Wang
- LP Jordheim
- LP Jordheim
- LV Mendelman
- M Anglana
- M Ferracin
- M J C Long
- M Li
- M Sahlin
- MA Rahman
- MD Burkhalter
- MS Duxbury
- MS Duxbury
- N Sabouri
- N Yokomakura
- O Guittet
- O Guittet
- OB Kashlan
- P Ceppi
- P Hakansson
- P Nordlund
- P Reichard
- P Reichard
- P Wonganan
- PJ Stover
- PL Bonate
- PS Ward
- R Hehlmann
- R Rofougaran
- R S Weiss
- RA Burrell
- RA Finch
- RA Hurta
- S Courbet
- S Eriksson
- S Faderl
- S Gon
- S Lindemalm
- S Mannava
- S Mannava
- S Matsushita
- S Nakahira
- S Nyholm
- S Walker
- S Yanamoto
- S Yanamoto
- S Yanamoto
- SB Fisher
- SJ Elledge
- T Itoi
- T Kimura
- T Morikawa
- T Morikawa
- T Spasokoukotskaja
- T Spasokoukotskaja
- T Yamaguchi
- TB Chaston
- TF Reubold
- TM Avolio
- U Uhlin
- V D'Angiolella
- VA Levin
- VI Avramis
- W Gong
- W Plunkett
- X Dong
- X Liu
- X Liu
- X Liu
- X Xu
- XJ Ma
- XQ Ge
- Y Aye
- Y Aye
- Y Aye
- Y Aye
- Y Engström
- Y Engström
- Y Engström
- Y Fu
- Y Lee
- Y Meyer
- Y Sterkers
- YK Oh
- YW Zhang
- Z Zheng
- ZP Lin
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
The impact of space experiments on our knowledge of the physics of the universe
- Author
- A Brown
- A Bruch
- A Cavaliere
- A Comastri
- A Dalgarno
- A Dar
- A Dar
- A Dar
- A Dar
- A Dar
- A Dar
- A Davidsen
- A de Rujula
- A Dressler
- A Giangrande
- A Guarnieri
- A Hewish
- A Khokhlov
- A Krabbe
- A Lawrence
- A Maeder
- A Magazzú
- A Mckellar
- A Mckellar
- A Omont
- A Panaitescu
- A Savage
- A Skumanich
- A Smialkowski
- A Smith
- A Solinger
- A Soltan
- A Songaila
- A Stebbins
- A Tiengo
- A Ulla
- A Withworth
- A. Guarnieri
- A. Krabbe
- A. Santangelo
- A. Scheepmaker
- A.A. Schwarzenberg-Czerny
- A.D. Kerrick
- A.N. Parmar
- A.N. Ramaprakash
- A.W. Strong
- A.W. Strong
- AA Leir
- AA Penzias
- AA Watson
- AA Zdziarski
- AA Zdziarski
- AA Zdziarski
- AB Solinger
- AC Cameron
- AC Fabian
- AC Fabian
- AC Fabian
- AC Fabian
- AD Erlykin
- AD Erlykin
- AD Erlykin
- AD Erlykin
- AD Erlykin
- AE Metzger
- AF Davidsen
- AF Illarionov
- AFJ Moffat
- AGW Cameron
- AGW Cameron
- AGW Cameron
- AH Barrett
- AH Bridle
- AH Joy
- AH Joy
- AH Joy
- AH Joy
- AJr Oemler
- AK Dupree
- AK Dupree
- AK Harding
- AK Harding
- AL Kiplinger
- AM Boesgaard
- AM Ghez
- AM Hillas
- AM Hillas
- AM Hillas
- AMT Pollock
- AN Parmar
- AN Witt
- AP Lightman
- AP Marscher
- AP Marscher
- AS Eddington
- Aschenbach
- AV Filippenko
- AW Strong
- AW Strong
- AW Strong
- AW Strong
- AW Strong
- AW Wolfendale
- AW Wolfendale
- B Alessandro
- B Aschenbach
- B Aschenbach
- B Aschenbach
- B Binggeli
- B Kozlovsky
- B Moore
- B Paczynski
- B Smith
- B Stern
- B Tinsley
- B Tinsley
- B Warner
- B Warner
- B Zuckerman
- B Zuckerman
- B Zuckerman
- B.E. Schaefer
- B.J. Wills
- B.N. Swanenburg
- B.N. Swanenburg
- B.T. Cleveland
- B.T. Soifer
- BA Wilking
- Bałuci´nska-Church M.
- BB Rossi
- BD Savage
- BD Savage
- BD Savage
- BEJ Pagel
- BJ Carr
- BJ Sams
- BJ Weiner
- BJM Hassall
- BJM Hassall
- BL Dingus
- BL Webster
- BM Belli
- BM Belli
- BM Haisch
- BM Haisch
- BM Tinsley
- Bolton. C.T.
- BT Draine
- BT Draine
- BT Soifer
- BT Soifer
- BT Soifer
- C Barat
- C Bartolini
- C Beichman
- C Bertout
- C Bertout
- C Bertout
- C Boulanger
- C Catala
- C Catala
- C Hazard
- C Jones
- C Jones
- C Knigge
- C la Dous
- C Martin
- C Martin
- C Rhoads
- C Sánchez-Fernández
- C Terquem
- C Thompson
- C Thompson
- C Thompson
- C-C Wu
- C. Athanassopoulos
- C. Catala
- C. Fransson
- C. Loore
- C. Montigny
- C.A. Beichman
- C.E. Fichtel
- C.E. Fichtel
- C.L. Bennett
- CA Beichman
- CB Stephenson
- CD Dermer
- CD Garmany
- CE Albert
- CE Fichtel
- CF Mckee
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- D Alexander
- D Barret
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- D Kunth
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- D Mccammon
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- D.C. Backer
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- Fukuda Y., et Super-KAMIOKANDE Collaboration
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- G.E. Allen
- G.E. Allen
- G.F. Smoot
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- N Devereux
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- P Giommi
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- P Jakobsen
- P Lena
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- P Predehl
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- P.G. Mezger
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- S Bowyer
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- T Piran
- T Piran
- T Piran
- T Simon
- T Stanev
- T Stanev
- T Takahashi
- T. Belloni
- T. Salvo
- T. Tamura
- T. Tanimori
- T.E. Strohmayer
- T.J. Galama
- T.J. Galama
- T.J. Galama
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- TiPei Li
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- TJ Sodorski
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- V Trimble
- V Trimble
- V Trimble
- V Trimble
- V Trimble
- V Trimble
- V Trimble
- V Trimble
- V Trimble
- VA Arbatsumian
- VA Arbatsumian
- van der Hucht K.A., Olnon, F.M.
- van der Veen
- van Paradijs
- van Paradijs
- VF Hess
- VF Polcaro
- VF Polcaro
- VF Polcaro
- VF Polcaro
- VG Kornilov
- VI Zatsepin
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- VM Lipunov
- W Baade
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- W Bednarek
- W Bednarek
- W Bednarek
- W Brinkmann
- W Chen
- W Forman
- W Forman
- W Forman
- W Forman
- W Forman
- W Forman
- W Hermsen
- W Hu
- W Krzeminski
- W Krzeminski
- W Ku
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- W Zhang
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- W. Collmar
- W. Forman
- W. Zhang
- W.A. Wheaton
- W.B. Honey
- W.N. Johnson
- W.R. Purcell
- W.R. Purcell
- W.W.M. Allison
- WA Mahoney
- WC Priedhorsky
- WC Priedhorsky
- WD Arnet
- WG Mathews
- WK Gear
- WN Christiansen
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- WRF Dent
- WS Adams
- WS Stahler
- WW Morgan
- X Chi
- X Chi
- X Chi
- Y Avni
- Y Avni
- Y Gao
- Y Ikebe
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- Y Suzuki
- Y Tanaka
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- Y. Fukuda
- Y. Ueda
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- Y. Ueda
- YM Georgelin
- YP Viala
- YuN Gnedin
- YuN Gnedin
- Zel’dovich Ya.,B., Sunyaev, R.A.
- Publication venue
- Springer
- Publication date
- 01/01/2004
- Field of study
Searches for Gravitational Waves from Known Pulsars at Two Harmonics in the Second and Third LIGO-Virgo Observing Runs
- Author
- Abbott R
- Abe H
- Acernese F
- Ackley K
- Adhikari N
- Adhikari RX
- Adkins VK
- Adya VB
- Affeldt C
- Agarwal D
- Agathos M
- Agatsuma K
- Aggarwal N
- Aguiar OD
- Aiello L
- Ain A
- Ajith P
- Akutsu T
- Albanesi S
- Alfaidi RA
- Allocca A
- Altin PA
- Amato A
- Anand C
- Anand S
- Ananyeva A
- Anderson SB
- Anderson WG
- Ando M
- Andrade T
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- Andres-Carcasona M
- Andric T
- Angelova SV
- Ansoldi S
- Antelis JM
- Antier S
- Antonopoulou D
- Apostolatos T
- Appavuravther EZ
- Appert S
- Apple SK
- Arai K
- Araya A
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- Areeda JS
- Arellano FEP
- Arene M
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- Arogeti M
- Aronson SM
- Arun KG
- Arzoumanian Z
- Asada H
- Asali Y
- Ashton G
- Aso Y
- Assiduo M
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- Badaracco F
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- Bailes M
- Baird J
- Bajpai R
- Baka T
- Ball M
- Ballardin G
- Ballmer SW
- Balsamo A
- Baltus G
- Banagiri S
- Banerjee B
- Bankar D
- Barayoga JC
- Barbieri C
- Barish BC
- Barker D
- Barneo P
- Barone F
- Barr B
- Barsotti L
- Barsuglia M
- Barta D
- Bartlett J
- Barton MA
- Bartos I
- Basak S
- Bassiri R
- Basti A
- Basu A
- Bawaj M
- Bayley JC
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- Becher BR
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- Bedakihale VM
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- Belahcene I
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- Bentley JD
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- Bergamin F
- Berger BK
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- Ewing BE
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- Zhu XJ
- Zhu ZH
- Zucker ME
- Zweizig J
- Publication venue
- 'American Astronomical Society'
- Publication date
- 01/01/2022
- Field of study
We present a targeted search for continuous gravitational waves (GWs) from 236 pulsars using data from the third observing run of LIGO and Virgo (O3) combined with data from the second observing run (O2). Searches were for emission from the l = m = 2 mass quadrupole mode with a frequency at only twice the pulsar rotation frequency (single harmonic) and the l = 2, m = 1, 2 modes with a frequency of both once and twice the rotation frequency (dual harmonic). No evidence of GWs was found, so we present 95% credible upper limits on the strain amplitudes h (0) for the single-harmonic search along with limits on the pulsars' mass quadrupole moments Q (22) and ellipticities epsilon. Of the pulsars studied, 23 have strain amplitudes that are lower than the limits calculated from their electromagnetically measured spin-down rates. These pulsars include the millisecond pulsars J0437-4715 and J0711-6830, which have spin-down ratios of 0.87 and 0.57, respectively. For nine pulsars, their spin-down limits have been surpassed for the first time. For the Crab and Vela pulsars, our limits are factors of similar to 100 and similar to 20 more constraining than their spin-down limits, respectively. For the dual-harmonic searches, new limits are placed on the strain amplitudes C (21) and C (22). For 23 pulsars, we also present limits on the emission amplitude assuming dipole radiation as predicted by Brans-Dicke theory
Search for Subsolar-Mass Binaries in the First Half of Advanced LIGO's and Advanced Virgo's Third Observing Run
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- Unnikrishnan CS
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- Vajente G
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- Wysocki DM
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- Yamazaki R
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- Yang KZ
- Yang L
- Yang Y
- Yang Y-C
- Yang Yang
- Yap MJ
- Yeeles DW
- Yeh S-W
- Yelikar AB
- Ying M
- Yokoyama J
- Yokozawa T
- Yoo J
- Yoshioka T
- Yu Hang
- Yu Haocun
- Yuzurihara H
- Zadrozny A
- Zanolin M
- Zeidler S
- Zelenova T
- Zendri J-P
- Zevin M
- Zhan M
- Zhang H
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- Zhao G
- Zhao Y
- Zhao Yue
- Zhou R
- Zhou Z
- Zhu XJ
- Zhu Z-H
- Zimmerman AB
- Zucker ME
- Zweizig J
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2022
- Field of study
We report on a search for compact binary coalescences where at least one binary component has a mass between 0.2 M and 1.0 M in Advanced LIGO and Advanced Virgo data collected between 1 April 2019 1500 UTC and 1 October 2019 1500 UTC. We extend our previous analyses in two main ways: we include data from the Virgo detector and we allow for more unequal mass systems, with mass ratio q≥0.1. We do not report any gravitational-wave candidates. The most significant trigger has a false alarm rate of 0.14 yr-1. This implies an upper limit on the merger rate of subsolar binaries in the range [220-24200] Gpc-3 yr-1, depending on the chirp mass of the binary. We use this upper limit to derive astrophysical constraints on two phenomenological models that could produce subsolar-mass compact objects. One is an isotropic distribution of equal-mass primordial black holes. Using this model, we find that the fraction of dark matter in primordial black holes in the mass range 0.2 M<1.0 M is fPBHωPBH/ωDM6%. This improves existing constraints on primordial black hole abundance by a factor of ∼3. The other is a dissipative dark matter model, in which fermionic dark matter can collapse and form black holes. The upper limit on the fraction of dark matter black holes depends on the minimum mass of the black holes that can be formed: the most constraining result is obtained at Mmin=1 M, where fDBHωDBH/ωDM0.003%. These are the first constraints placed on dissipative dark models by subsolar-mass analyses
Recommended from our members
Constraints on the Cosmic Expansion History from GWTC–3
- Author
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- Yeh S-W
- Yelikar AB
- Ying M
- Yokoyama J
- Yokozawa T
- Yoo J
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- Yu Hang
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- Yuzurihara H
- Zadrożny A
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- Zhu Z-H
- Zimmerman AB
- Zucker ME
- Zweizig J
- Publication venue
- The Astrophysical Journal
- Publication date
- 07/06/2023
- Field of study
Abstract
We use 47 gravitational wave sources from the Third LIGO–Virgo–Kamioka Gravitational Wave Detector Gravitational Wave Transient Catalog (GWTC–3) to estimate the Hubble parameter H(z), including its current value, the Hubble constant H
0. Each gravitational wave (GW) signal provides the luminosity distance to the source, and we estimate the corresponding redshift using two methods: the redshifted masses and a galaxy catalog. Using the binary black hole (BBH) redshifted masses, we simultaneously infer the source mass distribution and H(z). The source mass distribution displays a peak around 34 M
⊙, followed by a drop-off. Assuming this mass scale does not evolve with the redshift results in a H(z) measurement, yielding
H
0
=
68
−
8
+
12
km
s
−
1
Mpc
−
1
(68% credible interval) when combined with the H
0 measurement from GW170817 and its electromagnetic counterpart. This represents an improvement of 17% with respect to the H
0 estimate from GWTC–1. The second method associates each GW event with its probable host galaxy in the catalog GLADE+, statistically marginalizing over the redshifts of each event’s potential hosts. Assuming a fixed BBH population, we estimate a value of
H
0
=
68
−
6
+
8
km
s
−
1
Mpc
−
1
with the galaxy catalog method, an improvement of 42% with respect to our GWTC–1 result and 20% with respect to recent H
0 studies using GWTC–2 events. However, we show that this result is strongly impacted by assumptions about the BBH source mass distribution; the only event which is not strongly impacted by such assumptions (and is thus informative about H
0) is the well-localized event GW190814.</jats:p
Searches for gravitational waves from known pulsars at two harmonics in the second and third LIGO-Virgo observing runs
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- Wysocki DM
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- Yap MJ
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- Yeh S-W
- Yelikar AB
- Ying M
- Yokoyama J
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- Yu H
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- Zadrożny A
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- Zhu XJ
- Zhu Z-H
- Zucker ME
- Zweizig J
- Publication venue
- 'American Astronomical Society'
- Publication date
- 25/05/2022
- Field of study
We present a targeted search for continuous gravitational waves (GWs) from 236 pulsars using data from the third observing run of LIGO and Virgo (O3) combined with data from the second observing run (O2). Searches were for emission from the l = m = 2 mass quadrupole mode with a frequency at only twice the pulsar rotation frequency (single harmonic) and the l = 2, m = 1, 2 modes with a frequency of both once and twice the rotation frequency (dual harmonic). No evidence of GWs was found, so we present 95% credible upper limits on the strain amplitudes h0 for the single-harmonic search along with limits on the pulsars' mass quadrupole moments Q22 and ellipticities ε. Of the pulsars studied, 23 have strain amplitudes that are lower than the limits calculated from their electromagnetically measured spin-down rates. These pulsars include the millisecond pulsars J0437−4715 and J0711−6830, which have spin-down ratios of 0.87 and 0.57, respectively. For nine pulsars, their spin-down limits have been surpassed for the first time. For the Crab and Vela pulsars, our limits are factors of ∼100 and ∼20 more constraining than their spin-down limits, respectively. For the dual-harmonic searches, new limits are placed on the strain amplitudes C21 and C22. For 23 pulsars, we also present limits on the emission amplitude assuming dipole radiation as predicted by Brans-Dicke theory
Search for Subsolar-Mass Binaries in the First Half of Advanced LIGO’s and Advanced Virgo’s Third Observing Run
- Author
- Abbott R
- Abe H
- Acernese F
- Ackley K
- Adhikari N
- Adhikari RX
- Adkins VK
- Adya VB
- Affeldt C
- Agarwal D
- Agathos M
- Agatsuma K
- Aggarwal N
- Aguiar OD
- Aiello L
- Ain A
- Ajith P
- Akutsu T
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- Publication venue
- Publication date
- 24/09/2021
- Field of study
International audienceWe report on a search for compact binary coalescences where at least one binary component has a mass between 0.2 M⊙ and 1.0 M⊙ in Advanced LIGO and Advanced Virgo data collected between 1 April 2019 1500 UTC and 1 October 2019 1500 UTC. We extend our previous analyses in two main ways: we include data from the Virgo detector and we allow for more unequal mass systems, with mass ratio q≥0.1. We do not report any gravitational-wave candidates. The most significant trigger has a false alarm rate of 0.14 yr-1. This implies an upper limit on the merger rate of subsolar binaries in the range [220−24200] Gpc-3 yr-1, depending on the chirp mass of the binary. We use this upper limit to derive astrophysical constraints on two phenomenological models that could produce subsolar-mass compact objects. One is an isotropic distribution of equal-mass primordial black holes. Using this model, we find that the fraction of dark matter in primordial black holes in the mass range 0.2 M⊙<mPBH<1.0 M⊙ is fPBH≡ΩPBH/ΩDM≲6%. This improves existing constraints on primordial black hole abundance by a factor of ∼3. The other is a dissipative dark matter model, in which fermionic dark matter can collapse and form black holes. The upper limit on the fraction of dark matter black holes depends on the minimum mass of the black holes that can be formed: the most constraining result is obtained at Mmin=1 M⊙, where fDBH≡ΩDBH/ΩDM≲0.003%. These are the first constraints placed on dissipative dark models by subsolar-mass analyses
Search for gravitational waves from Scorpius X-1 with a hidden Markov model in O3 LIGO data
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- Zimmerman AB
- Zucker ME
- Zweizig J
- Publication venue
- HAL CCSD
- Publication date
- 01/01/2022
- Field of study
Results are presented for a semi-coherent search for continuous gravitational waves from the low-mass X-ray binary Scorpius X-1, using a hidden Markov model (HMM) to allow for spin wandering. This search improves on previous HMM-based searches of Laser Interferometer Gravitational-wave Observatory (LIGO) data by including the orbital period in the search template grid, and by analyzing data from the latest (third) observing run (O3). In the frequency range searched, from 60 to 500 Hz, we find no evidence of gravitational radiation. This is the most sensitive search for Scorpius X-1 using a HMM to date. For the most sensitive sub-band, starting at 256.06Hz, we report an upper limit on gravitational wave strain (at 95% confidence) of h095%=6.16×10−26, assuming the orbital inclination angle takes its electromagnetically restricted value ι=44∘. The upper limits on gravitational wave strain reported here are on average a factor of ∼3 lower than in the O2 HMM search. This is the first Scorpius X-1 HMM search with upper limits that reach below the indirect torque-balance limit for certain sub-bands, assuming ι=44∘