1,275 research outputs found
Clergy, crusified within the body of Christ - a challenge to pastoral care
M.A. Thesis / University of Pretoria / Department of Practical Theology / Advised by Prof M MasangoA tree is known by its fruit (Matthew 7:16), and a personâs priorities are known by reading his diary! We try so hard to be something we are not and often we succeed, ⊠but it is only for a short moment, or maybe twoâŠ
The words you and I speak become a mirror, reflecting our heartâs content to whoever wants to listen. James asks this question; âCan both fresh water and salt water flow from the same spring?â (James 3:11 - NIV) How then, is it possible to speak peace and war from the same tongue? How could I bless and curse, all in one breath? How could I declare my love for my Lord, yet crucify him from the same heart? How could I love my neighbour with bloodstained hands?
How could we declare victory in the cross at Calvary, where our Saviour died? How could we claim to be victorious in Jesus, saying that we will reign with him forever, (Rev 22: 5) and yet, as Christians, we are crucified over and over again?
This is the true mystery in Christ; there is victory in defeat, there is strength in weakness, there is life after death
No evidence of an 11.16 MeV 2+ state in 12C
An experiment using the 11B(3He,d)12C reaction was performed at iThemba LABS
at an incident energy of 44 MeV and analyzed with a high energy-resolution
magnetic spectrometer, to re-investigate states in 12C published in 1971. The
original investigation reported the existence of an 11.16 MeV state in 12C that
displays a 2+ nature. In the present experiment data were acquired at
laboratory angles of 25-, 30- and 35- degrees, to be as close to the c.m.
angles of the original measurements where the clearest signature of such a
state was observed. These new low background measurements revealed no evidence
of the previously reported state at 11.16 MeV in 12C
Approach to the semiconductor cavity QED in high-Q regimes with q-deformed boson
The high density Frenkel exciton which interacts with a single mode
microcavity field is dealed with in the framework of the q-deformed boson. It
is shown that the q-defomation of bosonic commutation relations is satisfied
naturally by the exciton operators when the low density limit is deviated. An
analytical expression of the physical spectrum for the exciton is given by
using of the dressed states of the cavity field and the exciton. We also give
the numerical study and compare the theoretical results with the experimental
resultsComment: 6 pages, 2 figure
Atropselective syntheses of (-) and (+) rugulotrosin A utilizing point-to-axial chirality transfer
Chiral, dimeric natural products containing complex structures and interesting biological properties have inspired chemists and biologists for decades. A seven-step total synthesis of the axially chiral, dimeric tetrahydroxanthone natural product rugulotrosin A is described. The synthesis employs a one-pot Suzuki coupling/dimerization to generate the requisite 2,2'-biaryl linkage. Highly selective point-to-axial chirality transfer was achieved using palladium catalysis with achiral phosphine ligands. Single X-ray crystal diffraction data were obtained to confirm both the atropisomeric configuration and absolute stereochemistry of rugulotrosin A. Computational studies are described to rationalize the atropselectivity observed in the key dimerization step. Comparison of the crude fungal extract with synthetic rugulotrosin A and its atropisomer verified that nature generates a single atropisomer of the natural product.P50 GM067041 - NIGMS NIH HHS; R01 GM099920 - NIGMS NIH HHS; GM-067041 - NIGMS NIH HHS; GM-099920 - NIGMS NIH HH
Revival of the magnetar PSR J1622-4950: observations with MeerKAT, Parkes, XMM-Newton, Swift, Chandra, and NuSTAR
New radio (MeerKAT and Parkes) and X-ray (XMM-Newton, Swift, Chandra, and
NuSTAR) observations of PSR J1622-4950 indicate that the magnetar, in a
quiescent state since at least early 2015, reactivated between 2017 March 19
and April 5. The radio flux density, while variable, is approximately 100x
larger than during its dormant state. The X-ray flux one month after
reactivation was at least 800x larger than during quiescence, and has been
decaying exponentially on a 111+/-19 day timescale. This high-flux state,
together with a radio-derived rotational ephemeris, enabled for the first time
the detection of X-ray pulsations for this magnetar. At 5%, the 0.3-6 keV
pulsed fraction is comparable to the smallest observed for magnetars. The
overall pulsar geometry inferred from polarized radio emission appears to be
broadly consistent with that determined 6-8 years earlier. However, rotating
vector model fits suggest that we are now seeing radio emission from a
different location in the magnetosphere than previously. This indicates a novel
way in which radio emission from magnetars can differ from that of ordinary
pulsars. The torque on the neutron star is varying rapidly and unsteadily, as
is common for magnetars following outburst, having changed by a factor of 7
within six months of reactivation.Comment: Published in ApJ (2018 April 5); 13 pages, 4 figure
Cross-sections for nuclide production in 56Fe target irradiated by 300, 500,750, 1000, 1500, and 2600 MeV protons compared with data on hydrogen target irradiation by 300, 500, 750, 1000, and 1500 MeV/nucleon 56Fe ions
Cross-sections for radioactive nuclide production in 56Fe(p,x) reactions at
300, 500, 750, 1000, 1500, and 2600 MeV were measured using the ITEP U-10
proton accelerator. In total, 221 independent and cumulative yields of products
of half-lives from 6.6 min to 312 days have been obtained via the
direct-spectrometry method. The measured data have been compared with the
experimental data obtained elsewhere by the direct and inverse kinematics
methods and with calculations by 15 codes, namely: MCNPX (INCL, CEM2k, BERTINI,
ISABEL), LAHET (BERTINI, ISABEL), CEM03 (.01, .G1, .S1), LAQGSM03 (.01, .G1,
>.S1), CASCADE-2004, LAHETO, and BRIEFF. Most of our data are in a good
agreement with the inverse kinematics results and disprove the results of some
earlier activation measurements that were quite different from the inverse
kinematics measurements. The most significant calculation-to-experiment
differences are observed in the yields of the A<30 light nuclei, indicating
that further improvements in nuclear reaction models are needed, and pointing
out as well to a necessity of more complete measurements of such reactions.Comment: 53 pages, 9 figures, 6 tables, only pdf file, submitted to Phys. Rev.
A risk prediction model for the assessment and triage of women with hypertensive disorders of pregnancy in low-resourced settings: the miniPIERS (Pre-eclampsia Integrated Estimate of RiSk) multi-country prospective cohort study.
BACKGROUND: Pre-eclampsia/eclampsia are leading causes of maternal mortality and morbidity, particularly in low- and middle- income countries (LMICs). We developed the miniPIERS risk prediction model to provide a simple, evidence-based tool to identify pregnant women in LMICs at increased risk of death or major hypertensive-related complications. METHODS AND FINDINGS: From 1 July 2008 to 31 March 2012, in five LMICs, data were collected prospectively on 2,081 women with any hypertensive disorder of pregnancy admitted to a participating centre. Candidate predictors collected within 24 hours of admission were entered into a step-wise backward elimination logistic regression model to predict a composite adverse maternal outcome within 48 hours of admission. Model internal validation was accomplished by bootstrapping and external validation was completed using data from 1,300 women in the Pre-eclampsia Integrated Estimate of RiSk (fullPIERS) dataset. Predictive performance was assessed for calibration, discrimination, and stratification capacity. The final miniPIERS model included: parity (nulliparous versus multiparous); gestational age on admission; headache/visual disturbances; chest pain/dyspnoea; vaginal bleeding with abdominal pain; systolic blood pressure; and dipstick proteinuria. The miniPIERS model was well-calibrated and had an area under the receiver operating characteristic curve (AUC ROC) of 0.768 (95% CI 0.735-0.801) with an average optimism of 0.037. External validation AUC ROC was 0.713 (95% CI 0.658-0.768). A predicted probability â„25% to define a positive test classified women with 85.5% accuracy. Limitations of this study include the composite outcome and the broad inclusion criteria of any hypertensive disorder of pregnancy. This broad approach was used to optimize model generalizability. CONCLUSIONS: The miniPIERS model shows reasonable ability to identify women at increased risk of adverse maternal outcomes associated with the hypertensive disorders of pregnancy. It could be used in LMICs to identify women who would benefit most from interventions such as magnesium sulphate, antihypertensives, or transportation to a higher level of care
Chronic depression symptoms and salivary NOx are associated with retinal vascular dysregulation: the SABPA study.
Background Depression has been associated with impaired nitric oxide (NO)-mediated vasodilation and vascular dysregulation (VD). Whether depression and NO levels will disturb retinal hemodynamics is not clear.
Objectives and methods Associations between the retinal vasculature, diastolic ocular perfusion pressure (DOPP) as measure of hypoperfusion, NO metabolites (NOx) and depression symptoms were assessed. Chronic VD risk markers [depression symptoms (Patient Health Questionnaire/PHQ-9 ℠10) and 24h pulse pressure] were determined in a bi-ethnic cohort (n=313; 48.6 ± 9 years; 53.9% men). At 3 year follow-up, retinal vessel calibre and retinopathy signs were quantified from digital images. Salivary NOx, a novel approach, was obtained pre- and post-flicker light-induced provocation (FLIP). DOPP was defined as diastolic blood pressure minus intraocular pressure.
Results Chronic VD risk was evident in Blacks opposed to acute risk in Whites (P<0.05). At follow-up, retinopathy (Blacks 60.4%/Whites 39.6%), lower pre-FLIP (”M) and higher post-FLIP NOx (%), arteriolar narrowing and wider venular calibre values were evident in Blacks compared to Whites, independent of confounders. A wider venular calibre, an index of stroke risk, was associated with chronic depression symptoms [cut point 248 MU: Area under the curve 0·61 (95% CI: 0·51, 0·72); 71% sensitivity; 55% specificity] as well as with hypoperfusion in the Blacks. In this group, arteriolar narrowing was associated with hypoperfusion; and attenuated arteriolar dilation with increased FLIP NOx responses (%).
Conclusions Higher NOx increased arteriolar vasoconstriction, presumably impeded perfusion and facilitated VD. Chronic depression symptoms may trigger disturbed NOx and retinal hemodynamics in Blacks and thereby potentiate stroke ris
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