222 research outputs found

    On the public discourse of religion : an analysis of Christianity in the United Kingdom

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    Debates over the involvement of religion in the public sphere look set to be one of the defining themes of the 21st century. But while religious issues have attracted a large degree of scholarly attention, the public discourse of religion itself, in terms of the effort to assert and legitimize a role for faith in the public realm, has remained notably under-researched. This article marks an initial step to address this deficiency by deconstructing the public discourse of Christianity in the United Kingdom. It argues that, while appealing for representation on the grounds of liberal equality, the overall goal of this discourse is to establish a role for itself as a principal source of moral authority, and to exempt itself from the evidentially-based standards and criteria that govern public life

    The Association between Proximity to Animal Feeding Operations and Community Health: A Systematic Review

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    Background: A systematic review was conducted for the association between animal feeding operations (AFOs) and the health of individuals living near AFOs. Methodology/Principal Findings: The review was restricted to studies reporting respiratory, gastrointestinal and mental health outcomes in individuals living near AFOs in North America, European Union, United Kingdom, and Scandinavia. From June to September 2008 searches were conducted in PUBMED, CAB, Web-of-Science, and Agricola with no restrictions. Hand searching of narrative reviews was also used. Two reviewers independently evaluated the role of chance, confounding, information, selection and analytic bias on the study outcome. Nine relevant studies were identified. The studies were heterogeneous with respect to outcomes and exposures assessed. Few studies reported an association between surrogate clinical outcomes and AFO proximity. A negative association was reported when odor was the measure of exposure to AFOs and self-reported disease, the measure of outcome. There was evidence of an association between selfreported disease and proximity to AFO in individuals annoyed by AFO odor. Conclusions/Significance: There was inconsistent evidence of a weak association between self-reported disease in people with allergies or familial history of allergies. No consistent dose response relationship between exposure and disease was observable

    Ecology of the free-living stages of 'Haemonchus contortus' in a cool temperate environment

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    Current understanding of the ecology of 'Haemonchus contortus' is incomplete and seen as an impediment to effective control of the worm in summer rainfall regions, where outbreaks are common and can result in significant stock mortality. Although there has been a wealth of published research on the effects of temperature on free-living development of 'H. contortus', our level of understanding of how moisture in the micro- and macro-environments influences development to infective larvae on herbage is considerably lower. The current state of knowledge of the free-living ecology of 'H. contortus' is reviewed in Chapter 2, with a particular focus on research findings since the 1970s. Knowledge gaps are highlighted, and a proposal made for a framework on which future investigations of 'H. contortus' can be based in order to improve prediction of free-living development. The key hypotheses under investigation in the experimental studies concerned the quantitative effects of moisture on free-living development of 'H. contortus', and are summarised in Chapter 1 and in further detail in each of the experimental chapters (Chapter 4-6). Plot experiments were conducted in the Northern Tablelands of NSW, where 'H. contortus' is the most important parasite of sheep. Subsequent laboratory experiments, designed in order to extend and explain the findings of the plot experiments, were conducted in programmable incubators in which temperature was regulated to mimic conditions typical to the Northern Tablelands summer. All experiments focused on testing the effects of a range of rainfall and moisture-related variables on 'H. contortus' development from egg through to infective larvae

    Expanding CubeSat Capabilities with a Low Cost Transceiver

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    CubeSats have developed rapidly over the past decade with the advent of a containerized deployer system and ever increasing launch opportunities. These satellites have moved from an educational tool to teach students about engineering challenges associated with satellite design, to systems that are conducting cutting edge earth, space and solar science. Early variants of the CubeSat had limited functionality and lacked sophisticated attitude control, deployable solar arrays and propulsion. This is no longer the case and as CubeSats mature, such systems are becoming commercially available. The result is a small satellite with sufficient power and pointing capabilities to support a high rate communication system. Communications systems have matured along with other CubeSat subsystems. Originally developed from amateur radio systems, CubeSats have generally operated in the VHF and UHF bands at data rates below 10 kbps (kilobits per second). More recently higher rate UHF systems have been developed, however these systems require a large collecting area on the ground to close the communications link at 3 Mbps (megabits per second). Efforts to develop systems that operate with similar throughput at S-Band (2-4 GHz (gigaherz)) and C-Band (4-8 GHz (gigaherz)) have also recently evolved. In this paper we outline an effort to develop a high rate CubeSat communication system that is compatible with the NASA Near Earth Network and can be accommodated by a CubeSat. The system will include a 200 kbps (kilobits per second) S-Band receiver and a 12.5 Mbps (megabits per second).X-Band transmitter. This paper will focus on our design approach and initial results associated with the 12.5 Mbps (megabits per second) X-band transmitter

    Competing Conservation Objectives for Predators and Prey: Estimating Killer Whale Prey Requirements for Chinook Salmon

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    Ecosystem-based management (EBM) of marine resources attempts to conserve interacting species. In contrast to single-species fisheries management, EBM aims to identify and resolve conflicting objectives for different species. Such a conflict may be emerging in the northeastern Pacific for southern resident killer whales (Orcinus orca) and their primary prey, Chinook salmon (Oncorhynchus tshawytscha). Both species have at-risk conservation status and transboundary (Canada–US) ranges. We modeled individual killer whale prey requirements from feeding and growth records of captive killer whales and morphometric data from historic live-capture fishery and whaling records worldwide. The models, combined with caloric value of salmon, and demographic and diet data for wild killer whales, allow us to predict salmon quantities needed to maintain and recover this killer whale population, which numbered 87 individuals in 2009. Our analyses provide new information on cost of lactation and new parameter estimates for other killer whale populations globally. Prey requirements of southern resident killer whales are difficult to reconcile with fisheries and conservation objectives for Chinook salmon, because the number of fish required is large relative to annual returns and fishery catches. For instance, a U.S. recovery goal (2.3% annual population growth of killer whales over 28 years) implies a 75% increase in energetic requirements. Reducing salmon fisheries may serve as a temporary mitigation measure to allow time for management actions to improve salmon productivity to take effect. As ecosystem-based fishery management becomes more prevalent, trade-offs between conservation objectives for predators and prey will become increasingly necessary. Our approach offers scenarios to compare relative influence of various sources of uncertainty on the resulting consumption estimates to prioritise future research efforts, and a general approach for assessing the extent of conflict between conservation objectives for threatened or protected wildlife where the interaction between affected species can be quantified

    Evaluation of intensive versus standard blood pressure reduction and association with cognitive decline and dementia : a systematic review and metaAnalysis

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    Importance: Optimal blood pressure (BP) targets for the prevention of cognitive impairment remain uncertain. Objective: To explore the association of intensive (i.e. lower than usual) BP reduction compared to guidelines on the incidence of cognitive decline and dementia in adults with hypertension. Data Sources and Study Selection: We conducted a systematic review and meta-analysis of randomized controlled trials that evaluated the association of intensive systolic BP lowering on cognitive outcomes by searching MEDLINE, Embase, CENTRAL, Web of Science, CINAHL, PsycINFO, ICTRP and ClinicalTrials.gov for data up to October 27, 2020. Data Extraction and Synthesis: Data screening and extraction were performed independently by two reviewers based on PRISMA guidelines. The risk of bias was assessed using the Cochrane risk-of-bias 2 tool. We used random-effects models using the inverse variance method for our pooled analyses. We evaluated the presence of potential heterogeneity with the I2 index. Main Outcomes and Measures: Our primary outcome was cognitive decline. Secondary outcomes included the incidence of dementia, mild cognitive impairment (MCI), cerebrovascular events, serious adverse events, and all-cause mortality. Results: From 7,755 citations, we identified sixteen publications from five trials (17,396 participants, mean age 65.7 years, 60.5% males) and two additional ongoing trials. All five trials included in quantitative analyses were considered at unclear to high risk of bias. The mean followup duration was 3.3 years (range 2.0 to 4.7 years). Intensive BP reduction was not significantly associated with global cognitive performance (SMD 0.01, 95% CI -0.04 to 0.06, I2 = 0%, four trials, 5,246 patients), incidence of dementia (RR 1.09, 95% CI 0.32 to 3.67, I2 = 27%, two trials, 9,444 patients) or incidence of MCI (RR 0.91, 95% CI 0.73 to 1.14, I2 = 74%, two trials, 10,774 patients) when compared to standard treatment. However, we found a reduction of cerebrovascular events in the intensive arm (RR 0.79, 95% CI 0.67-0.93, I2 = 0%, five trials, 17,396 patients) without an increased risk of serious adverse events or mortality. Conclusions and Relevance: We did not detect a significant association between BP reduction and lower risk of cognitive decline, dementia or MCI. The certainty of this evidence is low due to the limited sample size, the risk of bias of included trials and the observed statistical heterogeneity. Hence, current available evidence does not justify the use of lower BP targets for the prevention of cognitive decline and dementi
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