895 research outputs found
Anti-transglutaminase 6 antibodies in children and young adults with cerebral palsy.
Objectives. We have previously reported a high prevalence of gluten-related serological markers (GRSM) in children and young adults with cerebral palsy (CP). The majority had no enteropathy to suggest coeliac disease (CD). Antibodies against transglutaminase 6 (anti-TG6) represent a new marker associated with gluten-related neurological dysfunction. The aim of this study was to investigate the prevalence of anti-TG6 antibodies in this group of individuals with an early neurological injury resulting in CP. Materials and Methods. Sera from 96 patients with CP and 36 controls were analysed for IgA/IgG class anti-TG6 by ELISA. Results. Anti-TG6 antibodies were found in 12/96 (13%) of patients with CP compared to 2/36 (6%) in controls. The tetraplegic subgroup of CP had a significantly higher prevalence of anti-TG6 antibodies 6/17 (35%) compared to the other subgroups and controls. There was no correlation of anti-TG6 autoantibodies with seropositivity to food proteins including gliadin. Conclusions. An early brain insult and associated inflammation may predispose to future development of TG6 autoimmunity
Higher-order mesoscopic fluctuations in quantum wires: Conductance and current cumulants
We study conductance cumulants and current cumulants
related to heat and electrical transport in coherent mesoscopic quantum wires
near the diffusive regime. We consider the asymptotic behavior in the limit
where the number of channels and the length of the wire in the units of the
mean free path are large but the bare conductance is fixed. A recursion
equation unifying the descriptions of the standard and Bogoliubov--de Gennes
(BdG) symmetry classes is presented. We give values and come up with a novel
scaling form for the higher-order conductance cumulants. In the BdG wires, in
the presence of time-reversal symmetry, for the cumulants higher than the
second it is found that there may be only contributions which depend
nonanalytically on the wire length. This indicates that diagrammatic or
semiclassical pictures do not adequately describe higher-order spectral
correlations. Moreover, we obtain the weak-localization corrections to
with .Comment: 7 page
Transients in Power Systems
Power system engineering largely focuses on steady state analysis. The main areas of power system engineering are power flow studies and fault studies - both steady state technologies. But the world is largely transient, and power systems are always subject to time varying and short lived signals. This technical report concerns several important topics in transient analyses of power systems. The leading chapter deals with a new analytical tool-wavelets-for power system transients. Flicker and electric are furnace transients are discussed in Chapters I1 and IV. Chapter 111 deals with transients from shunt capacitor switching. The concluding chapters deal with transformer inrush current and non simultaneous pole closures of circuit breakers. This report was prepared by the students in EE532 at Purdue University. When I first came to Purdue in 1965, Professor El-Abiad was asking for student term projects which were turned into technical reports. I have \u27borrowed\u27 this idea and for many years we have produced technical reports from the power systems courses. The students get practice in writing reports, and the reader is able to get an idea of the coverage of our courses. I think that the students have done a good job on the subject of transients in power systems
Development of a cometosheath at comet 67P/Churuyumov-Gerasimenko: A case study comparison of Rosetta observations
Context: The ionosphere of a comet is known to deflect the solar wind through
mass loading, but the interaction is dependent on cometary activity. We
investigate the details of this process at comet 67P using the Rosetta Ion
Composition Analyzer. Aims: This study aims to compare the interaction of the
solar wind and cometary ions during two different time periods in the Rosetta
mission. Methods: We compared both the integrated ion moments (density,
velocity, and momentum flux) and the velocity distribution functions for two
days, four months apart. The velocity distribution functions were projected
into a coordinate system dependent on the magnetic field direction and averaged
over three hours. Results: The first case shows highly scattered H+ in both ion
moments and velocity distribution function. The He2+ ions are somewhat
scattered, but less so, and appear more like those of H2O+ pickup ions. The
second case shows characteristic evidence of mass-loading, where the solar wind
species are deflected, but the velocity distribution function is not
significantly changed. Conclusions: The distributions of H+ in the first case,
when compared to He2+ and H2O+ pickup ions, are indicative of a narrow
cometosheath on the scale of the H+ gyroradius. Thus, He2+ and H2O+, with
larger gyroradii, are largely able to pass through this cometosheath. An
examination of the momentum flux tensor suggests that all species in the first
case have a significant non-gyrotropic momentum flux component that is higher
than that of the second mass-loaded case. Mass loading is not a sufficient
explanation for the distribution functions and momentum flux tensor in the
first case, and so we assume this is evidence of bow shock formation.Comment: 14 pages, 9 figures, 3 tables, 2 video
Hybridization and Postprocessing Techniques for Mixed Eigenfunctions
We introduce hybridization and postprocessing techniques for the RaviartâThomas approximation of second-order elliptic eigenvalue problems. Hybridization reduces the RaviartâThomas approximation to a condensed eigenproblem. The condensed eigenproblem is nonlinear, but smaller than the original mixed approximation. We derive multiple iterative algorithms for solving the condensed eigenproblem and examine their interrelationships and convergence rates. An element-by-element postprocessing technique to improve accuracy of computed eigenfunctions is also presented. We prove that a projection of the error in the eigenspace approximation by the mixed method (of any order) superconverges and that the postprocessed eigenfunction approximations converge faster for smooth eigenfunctions. Numerical experiments using a square and an L-shaped domain illustrate the theoretical results
Microservice Transition and its Granularity Problem: A Systematic Mapping Study
Microservices have gained wide recognition and acceptance in software
industries as an emerging architectural style for autonomic, scalable, and more
reliable computing. The transition to microservices has been highly motivated
by the need for better alignment of technical design decisions with improving
value potentials of architectures. Despite microservices' popularity, research
still lacks disciplined understanding of transition and consensus on the
principles and activities underlying "micro-ing" architectures. In this paper,
we report on a systematic mapping study that consolidates various views,
approaches and activities that commonly assist in the transition to
microservices. The study aims to provide a better understanding of the
transition; it also contributes a working definition of the transition and
technical activities underlying it. We term the transition and technical
activities leading to microservice architectures as microservitization. We then
shed light on a fundamental problem of microservitization: microservice
granularity and reasoning about its adaptation as first-class entities. This
study reviews state-of-the-art and -practice related to reasoning about
microservice granularity; it reviews modelling approaches, aspects considered,
guidelines and processes used to reason about microservice granularity. This
study identifies opportunities for future research and development related to
reasoning about microservice granularity.Comment: 36 pages including references, 6 figures, and 3 table
Nonreciprocal Directional Dichroism and Toroidalmagnons in Helical Magnets
We investigate a dynamical magnetoelectric effect due to a magnetic resonance
in helical spin structures through the coupling between magnetization and
electric polarization via a spin current mechanism. We show that the magnon has
both the dynamical magnetic moment and the electric moment
(), i.e., a dynamical toroidal moment,
under external magnetic fields, and thus it is named the {\em toroidalmagnon}.
The toroidalmagnon exists in most conical spin structures owing to the
generality of the spin current mechanism. In the absorption of electromagnetic
waves, the toroidalmagnon excitation process generally induces a nonreciprocal
directional dichroism as a consequence of an interference of the magnetic and
electric responses.Comment: 5 pages, 2 figure
Financing Maternal and Child HealthâWhat Are the Limitations in Estimating Donor Flows and Resource Needs?
Marco SchÀferhoff and colleagues critique funding estimates for the maternal and child health Millennium Development Goals, and make recommendations for improving the tracking of financing flows and estimating the costs of scaling up interventions for mothers and children
Spatial distribution of low-energy plasma around 2 comet 67P/CG from Rosetta measurements
International audienceWe use measurements from the Rosetta plasma consortium (RPC) Langmuir probe (LAP) and mutual impedance probe (MIP) to study the spatial distribution of low-energy plasma in the near-nucleus coma of comet 67P/Churyumov-Gerasimenko. The spatial distribution is highly structured with the highest density in the summer hemisphere and above the region connecting the two main lobes of the comet, i.e. the neck region. There is a clear correlation with the neutral density and the plasma to neutral density ratio is found to be âŒ1-2·10 â6 , at a cometocentric distance of 10 km and at 3.1 AU from the sun. A clear 6.2 h modulation of the plasma is seen as the neck is exposed twice per rotation. The electron density of the collisonless plasma within 260 km from the nucleus falls of with radial distance as âŒ1/r. The spatial structure indicates that local ionization of neutral gas is the dominant source of low-energy plasma around the comet
Faire lâUnion. La refondation des parties de droite aprĂšs les Ă©lections de 2002
Un nouveau parti de droite, pour le moment dénommé UMP, a été mis en place entre des deux tours de
l'élection présidentielle. Cet article se donne pour objectif d'analyser les enjeux de cette transformation.
La genĂšse de l'UMP permet de saisir dans quelle mesure un parti poli-tique peut ĂȘtre conçu comme la
connexion d'un ensemble de systÚmes de coopération organisés autour de postes à conquérir. En effet,
l'impératif d'unification de la droite française est lié au décalage persistant existant entre les systÚmes
de coopération législatif et présidentiel. Mais les questions soulevées par cette fusion partisane (l'UMP
inclut le RPR, DL et une majeure partie de l'UDF) montrent que cette vision ne peut suffire et que les
partis ne sont pas seulement des systÚmes de coopération mais aussi des systÚmes de production.
DĂšs lors, leurs logiques d'organisation internes pĂšsent sur ce travail de transformation du social en
politique, de la plu-ralité en homogénéité. Dans le cas de l'UMP, il s'agit d'abord de mettre en commun
des modes de fonctionnement, en particulier de définir la place et la légitimité accordées
respectivement aux adhérents et aux élus, mais aussi d'organiser l'expression de la pluralité
idéologique par la mise en place de courants
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