Orbital operations study. Appendix B: Operational procedures

Operational procedures for each alternate approach for each interfacing activity of the orbital operations study are presented. The applicability of the procedures to interfacing element pairs is identified

Disparities in use of mental health and substance abuse services by Asian and Native Hawaiian/Other Pacific Islander women

The purpose of this study was to determine if disparities exist in lifetime utilization of mental health/substance abuse services among Asian, Native Hawaiian/Other Pacific Islander (NHOPI) and white mothers. The study sample was comprised of mothers assessed to be at-risk (n = 491) and not at-risk (n = 218) for child maltreatment in the Hawaii Healthy Start Program study. Multiple logistic regression models were used to test the effects of predisposing, need, and enabling factors on utilization of services. Results revealed that, among mothers with depressive symptoms, compared with whites, Asians and NHOPI were significantly less likely to have received services. There were no significant racial differences in use of mental health/substance use services by other factors. These results suggest that racial disparities exist in utilization of mental health/substance abuse services among mothers with depressive symptoms. Future research is needed to identify barriers and facilitators to accessing needed services for Asian and NHOPI women

Tunneling cosmological state revisited: Origin of inflation with a non-minimally coupled Standard Model Higgs inflaton

We suggest a path integral formulation for the tunneling cosmological state, which admits a consistent renormalization and renormalization group (RG) improvement in particle physics applications of quantum cosmology. We apply this formulation to the inflationary cosmology driven by the Standard Model (SM) Higgs boson playing the role of an inflaton with a strong non-minimal coupling to gravity. In this way a complete cosmological scenario is obtained, which embraces the formation of initial conditions for the inflationary background in the form of a sharp probability peak in the distribution of the inflaton field and the ongoing generation of the Cosmic Microwave Background (CMB) spectrum on this background. Formation of this probability peak is based on the same RG mechanism which underlies the generation of the CMB spectrum which was recently shown to be compatible with the WMAP data in the Higgs mass range $135.6 {\rm GeV} \lesssim M_H\lesssim 184.5 {\rm GeV}$. This brings to life a convincing unification of quantum cosmology with the particle phenomenology of the SM, inflation theory, and CMB observations.Comment: 18 pages, 3 figures, LaTe

Renormalization Group Flow in Scalar-Tensor Theories. II

We study the UV behaviour of actions including integer powers of scalar curvature and even powers of scalar fields with Functional Renormalization Group techniques. We find UV fixed points where the gravitational couplings have non-trivial values while the matter ones are Gaussian. We prove several properties of the linearized flow at such a fixed point in arbitrary dimensions in the one-loop approximation and find recursive relations among the critical exponents. We illustrate these results in explicit calculations in $d=4$ for actions including up to four powers of scalar curvature and two powers of the scalar field. In this setting we notice that the same recursive properties among the critical exponents, which were proven at one-loop order, still hold, in such a way that the UV critical surface is found to be five dimensional. We then search for the same type of fixed point in a scalar theory with minimal coupling to gravity in $d=4$ including up to eight powers of scalar curvature. Assuming that the recursive properties of the critical exponents still hold, one would conclude that the UV critical surface of these theories is five dimensional.Comment: 14 pages. v.2: Minor changes, some references adde

Supergravity based inflation models: a review

In this review, we discuss inflation models based on supergravity. After explaining the difficulties in realizing inflation in the context of supergravity, we show how to evade such difficulties. Depending on types of inflation, we give concrete examples, particularly paying attention to chaotic inflation because the ongoing experiments like Planck might detect the tensor perturbations in near future. We also discuss inflation models in Jordan frame supergravity, motivated by Higgs inflation.Comment: 30 pages, invited review for Classical and Quantum Gravity, published versio

Inflation from non-minimally coupled scalar field in loop quantum cosmology

The FRW model with non-minimally coupled massive scalar field has been investigated in LQC framework. Considered form of the potential and coupling allows applications to Higgs driven inflation. Out of two frames used in the literature to describe such systems: Jordan and Einstein frame, the latter one is applied. Specifically, we explore the idea of the Einstein frame being the natural 'environment' for quantization and the Jordan picture having an emergent nature. The resulting dynamics qualitatively modifies the standard bounce paradigm in LQC in two ways: (i) the bounce point is no longer marked by critical matter energy density, (ii) the Planck scale physics features the 'mexican hat' trajectory with two consecutive bounces and rapid expansion and recollapse between them. Furthermore, for physically viable coupling strength and initial data the subsequent inflation exceeds 60 e-foldings.Comment: Clarity improved. Replaced with revised version accepted in JCA

Correlation of the ratio of metastatic to non-metastatic cancer cases with the degree of socioeconomic deprivation among Texas counties

<p>Abstract</p> <p>Background</p> <p>Previous studies have demonstrated that cancer registrations and hospital discharge rate are closely correlated with census data-based socioeconomic deprivation indices. We hypothesized that communities with higher degrees of socioeconomic deprivation tend to have a higher ratio of metastatic to non-metastatic cancer cases (lung, breast, prostate, female genital system, colorectal cancers or all types of cancers combined). In this study, we investigate the potential link between this ratio and the Wellbeing Index (WI) among Texas counties.</p> <p>Results</p> <p>Cancer data in 2000 were provided by the Texas Cancer Registry, while data on the ten socioeconomic variables among the 254 Texas counties in 2000 for building the WI were obtained from U.S. Census Bureau. The ten socioeconomic status variables were subjected to the principal component analysis, and the first principal component scores were grouped into deciles for the WI (1 to 10) and the 254 Texas counties were classified into 10 corresponding groups. Weighted linear regression analyses and a Cochran-Armitage trend test were performed to determine the relationship between the ratio of age-adjusted metastatic to non-metastatic cancer incidence cases and WI. The ratios of metastatic to non-metastatic cases of female genital system cancer (<it>r</it>²= 0.84, <it>p </it>= 0.0002), all-type cancers (<it>r</it>²= 0.73, <it>p </it>= 0.0017) and lung cancer (<it>r</it>²= 0.54, <it>p </it>= 0.0156) at diagnosis were positively correlated with WI.</p> <p>Conclusions</p> <p>The ratios of metastatic to non-metastatic cases of all-type, female genital system and lung cancers at diagnosis were statistically correlated with socioeconomic deprivation. Potential mediators for the correlation warrant further investigation in order to reduce health disparities associated with socioeconomic inequality.</p

Search of scaling solutions in scalar-tensor gravity

We write new functional renormalization group equations for a scalar nonminimally coupled to gravity. Thanks to the choice of the parametrization and of the gauge fixing they are simpler than older equations and avoid some of the difficulties that were previously present. In three dimensions these equations admit, at least for sufficiently small fields, a solution that may be interpreted as a gravitationally dressed Wilson-Fisher fixed point. We also find for any dimension d>2 two analytic scaling solutions which we study for d=3 and d=4. One of them corresponds to the fixed point of the Einstein-Hilbert truncation, the others involve a nonvanishing minimal coupling

Time evolution of in vivo articular cartilage repair induced by bone marrow stimulation and scaffold implantation in rabbits

Purpose: Tissue engineering techniques were used to study cartilage repair over a 12-month period in a rabbit model. Methods: A full-depth chondral defect along with subchondral bone injury were originated in the knee joint, where a biostable porous scaffold was implanted, synthesized of poly(ethyl acrylate-co-hydroxyethyl acrylate) copolymer. Morphological evolution of cartilage repair was studied 1 and 2 weeks, and 1, 3, and 12 months after implantation by histological techniques. The 3-month group was chosen to compare cartilage repair to an additional group where scaffolds were preseeded with allogeneic chondrocytes before implantation, and also to controls, who underwent the same surgery procedure, with no scaffold implantation. Results: Neotissue growth was first observed in the deepest scaffold pores 1 week after implantation, which spread thereafter; 3 months later scaffold pores were filled mostly with cartilaginous tissue in superficial and middle zones, and with bone tissue adjacent to subchondral bone. Simultaneously, native chondrocytes at the edges of the defect started to proliferate 1 week after implantation; within a month those edges had grown centripetally and seemed to embed the scaffold, and after 3 months, hyaline-like cartilage was observed on the condylar surface. Preseeded scaffolds slightly improved tissue growth, although the quality of repair tissue was similar to non-preseeded scaffolds. Controls showed that fibrous cartilage was mainly filling the repair area 3 months after surgery. In the 12-month group, articular cartilage resembled the untreated surface. Conclusions: Scaffolds guided cartilaginous tissue growth in vivo, suggesting their importance in stress transmission to the cells for cartilage repair.This study was supported by the Spanish Ministry of Science and Innovation through MAT2010-21611-C03-00 project (including the FEDER financial support), by Conselleria de Educacion (Generalitat Valenciana, Spain) PROMETEO/2011/084 grant, and by CIBER-BBN en Bioingenieria, Biomateriales y Nanomedicina. The work of JLGR was partially supported by funds from the Generalitat Valenciana, ACOMP/2012/075 project. CIBER-BBN is an initiative funded by the VI National R&D&i Plan 2008-2011, Iniciativa Ingenio 2010, Consolider Program, CIBER Actions and financed by the - Instituto de Salud Carlos III with assistance from the European Regional Development Fund.Sancho-Tello Valls, M.; Forriol, F.; Gastaldi, P.; Ruiz Sauri, A.; Martín De Llano, JJ.; Novella-Maestre, E.; Antolinos Turpín, CM.... (2015). 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Disparities in preventive procedures: comparisons of self-report and Medicare claims data

BACKGROUND: Racial/ethnic disparities are assessed using either self-report or claims data. We compared these two data sources and examined contributors to discrepancies in estimates of disparities. METHODS: We analyzed self-report and matching claims data from Medicare Beneficiaries 65 and older who participated in the Medicare Current Beneficiary Survey, 1999–2002. Six preventive procedures were included: PSA testing, influenza vaccination, Pap smear testing, cholesterol testing, mammography, and colorectal cancer testing. We examined predictors of self-reports in the absence of claims and claims in the absence of self-reports. RESULTS: With the exception of PSA testing, racial/ethnic disparities in preventive procedures are generally larger when using Medicare claims than when using patients' self-report. Analyses adjusting for age, gender, income, educational level, health status, proxy response and supplemental insurance showed that minorities were more likely to self-report preventive procedures in the absence of claims. Adjusted odds ratios ranged from 1.07 (95% CI: 0.88 – 1.30) for PSA testing to 1.83 (95% CI: 1.46 – 2.30) for Pap smear testing. Rates of claims in the absence of self-report were low. Minorities were more likely to have PSA test claims in the absence of self-reports (1.55 95% CI: 1.17 – 2.06), but were less likely to have influenza vaccination claims in the absence of self-reports (0.69 95% CI: 0.51 – 0.93). CONCLUSION: These findings are consistent with either racial/ethnic reporting biases in receipt of preventive procedures or less efficient Medicare billing among providers with large minority practices