1,009 research outputs found
Graphite formation in cast iron, phase 2
Several types of cast irons are directionally solidified aboard the KC-135 aircraft. Also, control samples are run on Earth for comparison. Some of these samples are unusable because of various mechanical problems; the analysis and the interpretation of results on the samples that are run successfully is discussed
Computational Modeling of Channelrhodopsin-2 Photocurrent Characteristics in Relation to Neural Signaling
Channelrhodopsins-2 (ChR2) are a class of light sensitive proteins that offer
the ability to use light stimulation to regulate neural activity with
millisecond precision. In order to address the limitations in the efficacy of
the wild-type ChR2 (ChRwt) to achieve this objective, new variants of ChR2 that
exhibit fast mono-exponential photocurrent decay characteristics have been
recently developed and validated. In this paper, we investigate whether the
framework of transition rate model with 4 states, primarily developed to mimic
the bi-exponential photocurrent decay kinetics of ChRwt, as opposed to the low
complexity 3 state model, is warranted to mimic the mono-exponential
photocurrent decay kinetics of the newly developed fast ChR2 variants: ChETA
(Gunaydin et al., Nature Neurosci, 13:387-392, 2010) and ChRET/TC (Berndt et
al., PNAS, 108:7595-7600, 2011). We begin by estimating the parameters for the
3-state and 4-state models from experimental data on the photocurrent kinetics
of ChRwt, ChETA and ChRET/TC. We then incorporate these models into a
fast-spiking interneuron model (Wang and Buzsaki., J Neurosci,
16:6402-6413,1996) and a hippocampal pyramidal cell model (Golomb et al., J
Neurophysiol, 96:1912-1926, 2006) and investigate the extent to which the
experimentally observed neural response to various optostimulation protocols
can be captured by these models. We demonstrate that for all ChR2 variants
investigated, the 4 state model implementation is better able to capture neural
response consistent with experiments across wide range of optostimulation
protocol. We conclude by analytically investigating the conditions under which
the characteristic specific to the 3-state model, namely the mono-exponential
photocurrent decay of the newly developed variants of ChR2, can occurs in the
framework of the 4-state model.Comment: 10 figure
Citizen Engagement through Design Space Exploration Integrating citizen knowledge and expert design in computational urban planning
A common understanding exists that citizens should become more involved in thedesign, planning, and governance of the city. Due to a lack of common platformsand difficulties in the meaningful integration of the participatory input, however,the tools and methods currently employed in citizen engagement are often illconnected to the design and governance tools and processes used by experts. Inthis paper we describe a Grasshopper and Rhino based approach, which allowsdesigners to share a subset of the design space formed by parametric designvariants with citizens via the online interface Beta.Speckle. In a user study weevaluated the usability of the tool as well as studied the design choices ofparticipants, which were found to be influenced by preferences for visual orderand underlying economic, social, and environmental values. For the futuredesign of participatory exercises, it was concluded that indicators relating tocitizens' values and preferences will allow for a more effective exploration of thedesign space and increase the meaningfulness of results
A 10B-based neutron detector with stacked Multiwire Proportional Counters and macrostructured cathodes
We present the results of the measurements of the detection efficiency for a
4.7 \r{A} neutron beam incident upon a detector incorporating a stack of up to
five MultiWire Proportional Counters (MWPC) with Boron-coated cathodes. The
cathodes were made of Aluminum and had a surface exhibiting millimeter-deep
V-shaped grooves of 45{\deg}, upon which the thin Boron film was deposited by
DC magnetron sputtering. The incident neutrons interacting with the converter
layer deposited on the sidewalls of the grooves have a higher capture
probability, owing to the larger effective absorption film thickness. This
leads to a higher overall detection efficiency for the grooved cathode when
compared to a cathode with a flat surface. Both the experimental results and
the predictions of the GEANT4 model suggests that a 5-counter detector stack
with coated grooved cathodes has the same efficiency as a 7-counter stack with
flat cathodes. The reduction in the number of counters in the stack without
altering the detection efficiency will prove highly beneficial for large-area
position-sensitive detectors for neutron scattering applications, for which the
cost-effective manufacturing of the detector and associated readout electronics
is an important objective. The proposed detector concept could be a
technological option for one of the new chopper spectrometers and other
instruments planned to be built at the future European Spallation Source in
Sweden. These results with macrostructured cathodes generally apply not just to
MWPCs but to other gaseous detectors as well.Comment: 14 pages, 9 figure
Environmental factors influencing butterfly abundance after a severe wildfire in Mediterranean vegetation
Factores ambientales que influyen en la abundancia de mariposas después de un gran incendio forestal en la vegetación mediterráneaA pesar de la atención prestada a la ecología de los lepidópteros, en la región mediterránea poco se sabe acerca de las respuestas de sus comunidades a los incendios forestales. Aquí, evaluamos la comunidad de mariposas dos años después de un gran incendio forestal que afectó 13.000 ha en Cataluña (NE de España) en relación con el hábitat circundante no quemado, mediante transectos para censos visuales. Se examinaron varios parámetros de la comunidad, como la abundancia, la diversidad, la riqueza de especies y equitatividad, comparando las áreas quemadas y no quemadas. Se utilizó el análisis de correspondencias para analizar la composición específica y abundancia relativa de las especies en la comunidad. La influencia de las variables ambientales sobre la abundancia de algunas especies comunes se analizó con modelos mixtos lineales generalizados, teniendo en cuenta los efectos espaciales. No se encontraron diferencias significativas entre los tratamientos en los parámetros de la comunidad y no se detectó dominancia en la zona quemada. La estructura de la vegetación y la distribución geográfica de los transectos influyó en la ordenación de las especies y los transectos en el análisis de correpondencias, peró no se encontró ningún efecto evidente del fuego. Los resultados de los modelos lineales generalizados mixtos (GLMM) señalaron la importancia de la disponibilidad de néctar, el fuego y estructura de la vegetación para explicar la abundancia poblacional de la mayoría de las especies modelizadas.Despite the attention given to the ecology of butterflies, little is known about their community response to wildfires in the Mediterranean region. Here, we evaluated the butterfly assemblage two years after a severe, 13,000 ha wildfire in Catalonia (NE Spain) in relation to the surrounding unburned habitat. Using visual transect censuses we assessed community parameters such as abundance, diversity, species richness and equitability in burned and unburned areas. Correspondence analysis was used to analyse specific composition and relative abundance of species in the community. The influence of environmental variables on the abundance of some common species was analysed using generalized linear mixed models, taking spatial effects into account. No significant differences were found between areas for any of the community parameters, and no dominance was detected in the burned area. The structure of the vegetation and the geographical distribution of transects influenced the ordination of species and transects on the correspondence analysis plot. Generalized linear mixed models (GLMM) results underscored the role of nectar availability, fire and vegetation structure on the abundance of most species studied.Factores ambientales que influyen en la abundancia de mariposas después de un gran incendio forestal en la vegetación mediterráneaA pesar de la atención prestada a la ecología de los lepidópteros, en la región mediterránea poco se sabe acerca de las respuestas de sus comunidades a los incendios forestales. Aquí, evaluamos la comunidad de mariposas dos años después de un gran incendio forestal que afectó 13.000 ha en Cataluña (NE de España) en relación con el hábitat circundante no quemado, mediante transectos para censos visuales. Se examinaron varios parámetros de la comunidad, como la abundancia, la diversidad, la riqueza de especies y equitatividad, comparando las áreas quemadas y no quemadas. Se utilizó el análisis de correspondencias para analizar la composición específica y abundancia relativa de las especies en la comunidad. La influencia de las variables ambientales sobre la abundancia de algunas especies comunes se analizó con modelos mixtos lineales generalizados, teniendo en cuenta los efectos espaciales. No se encontraron diferencias significativas entre los tratamientos en los parámetros de la comunidad y no se detectó dominancia en la zona quemada. La estructura de la vegetación y la distribución geográfica de los transectos influyó en la ordenación de las especies y los transectos en el análisis de correpondencias, peró no se encontró ningún efecto evidente del fuego. Los resultados de los modelos lineales generalizados mixtos (GLMM) señalaron la importancia de la disponibilidad de néctar, el fuego y estructura de la vegetación para explicar la abundancia poblacional de la mayoría de las especies modelizadas
Experimental Performance of a Micromachined Heat Flux Sensor
Steady-state and frequency response calibration of a microfabricated heat-flux sensor have been completed. This sensor is batch fabricated using standard, micromachining techniques, allowing both miniaturization and the ability to create arrays of sensors and their corresponding interconnects. Both high-frequency and spatial response is desired, so the sensors are both thin and of small cross-sectional area. Thin-film, temperature-sensitive resistors are used as the active gauge elements. Two sensor configurations are investigated: (1) a Wheatstone-bridge using four resistors; and (2) a simple, two-resistor design. In each design, one resistor (or pair) is covered by a thin layer (5000 A) thermal barrier; the other resistor (or pair) is covered by a thick (5 microns) thermal barrier. The active area of a single resistor is 360 microns by 360 microns; the total gauge area is 1.5 mm square. The resistors are made of 2000 A-thick metal; and the entire gauge is fabricated on a 25 microns-thick flexible, polyimide substrate. Heat flux through the surface changes the temperature of the resistors and produces a corresponding change in resistance. Sensors were calibrated using two radiation heat sources: (1) a furnace for steady-state, and (2) a light and chopper for frequency response
Host specialization by Cotesia wasps (Hymenoptera: Braconidae) parasitizing species-rich Melitaeini (Lepidoptera: Nymphalidae) communities in north-eastern Spain
In order to investigate parasitoids of the genus Cotesia (Hymenoptera: Braconidae), larvae of a speciose group of butterflies, the tribe Melitaeini (Lepidoptera: Nymphalidae), were collected from several sites in Catalonia, northern Spain, a region that harbours ten out of the 20 European species of Melitaeini. New information on the natural history of the butterflies is presented, and the structure of their communities and patterns of larval parasitism are described. On the basis of mtDNA sequence data (COI gene), microsatellite data (ten loci) and behavioural experiments, we recognize seven biologically distinct species of Cotesia parasitizing the Melitaeini communities within this relatively small geographical area. In particular, the notional species C. melitaearum and C. acuminata each represents a series of cryptic species with narrow host associations. The possibility of direct competition among the parasitoids and/or indirect interactions between butterflies mediated by Cotesia parasitoids is explored
Validation of a Net Active Debris Removal Simulator within Parabolic Flight Experiment
Currently space debris is recognized as a major risk for space missions. In this frame it is involved the Patender project (Net parametric characterization and parabolic flight). The goal of this ESA funded activity (ending by March 2014) is to develop a confident mean to further investigate, develop and validate the concept of using nets for actively removing space debris of different characteristics. The net simulator will be validated in a parabolic flight experiment where microgravity conditions can be reached during some few tens of seconds. Different net shapes (pyramidal/planar) will be launched using a pneumatic-based dedicated mechanism in order to simulate the capture of a large space debris. High-speed motion cameras will record the experiment in order to allow the 3D reconstruction of the deployment and wrapping around the target phases and the validation of the software simulator
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