928 research outputs found

    Total quality in laboratory diagnostics: the role of commercial companies

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    Quality is a key focus for clinical laboratories, since it is viewed as a prerequisite for patient safety. It permeates all three phases of the total testing process (preanalytical, analytical and postanalytical), and relies heavily on the quality of diagnostic products, such as in vitro (IVD) devices (instruments, assays, reagents and specimen collection tubes) and medical devices (blood collection needles and sets). The diagnostic industry has implemented strict criteria to assure that the quality of their products throughout their life cycle meets the needs of their customers. This is accomplished through established processes to develop products that meet customer needs, as well as regulatory requirements needed to assure their safety and efficacy while adhering to good clinical practices and maintaining high level of safety of human subjects that participate in clinical trials. At the same time, the commercial companies follow good manufacturing practices to reduce variability within their manufacturing processes and deliver products that are within established specifications. However, the highest level of quality can only be achieved when instrument/assay manufacturers work closely with specimen containment manufacturers to assure total system performance

    Total quality in laboratory diagnostics: the role of commercial companies

    Get PDF
    Quality is a key focus for clinical laboratories, since it is viewed as a prerequisite for patient safety. It permeates all three phases of the total testing process (preanalytical, analytical and postanalytical), and relies heavily on the quality of diagnostic products, such as in vitro (IVD) devices (instruments, assays, reagents and specimen collection tubes) and medical devices (blood collection needles and sets). The diagnostic industry has implemented strict criteria to assure that the quality of their products throughout their life cycle meets the needs of their customers. This is accomplished through established processes to develop products that meet customer needs, as well as regulatory requirements needed to assure their safety and efficacy while adhering to good clinical practices and maintaining high level of safety of human subjects that participate in clinical trials. At the same time, the commercial companies follow good manufacturing practices to reduce variability within their manufacturing processes and deliver products that are within established specifications. However, the highest level of quality can only be achieved when instrument/assay manufacturers work closely with specimen containment manufacturers to assure total system performance

    Physical origin of the power-law tailed statistical distributions

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    Starting from the BBGKY hierarchy, describing the kinetics of nonlinear particle system, we obtain the relevant entropy and stationary distribution function. Subsequently, by employing the Lorentz transformations we propose the relativistic generalization of the exponential and logarithmic functions. The related particle distribution and entropy represents the relativistic extension of the classical Maxwell-Boltzmann distribution and of the Boltzmann entropy respectively and define the statistical mechanics presented in [Phys. Rev. E {\bf 66}, 056125 (2002)] and [Phys. Rev. E {\bf 72}, 036108 (2005). The achievements of the present effort, support the idea that the experimentally observed power law tailed statistical distributions in plasma physics, are enforced by the relativistic microscopic particle dynamics.Comment: 6 pages. arXiv admin note: substantial text overlap with arXiv:1110.3944, arXiv:1012.390

    Towards a Formal Verification Methodology for Collective Robotic Systems

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    We introduce a UML-based notation for graphically modeling systems’ security aspects in a simple and intuitive way and a model-driven process that transforms graphical specifications of access control policies in XACML. These XACML policies are then translated in FACPL, a policy language with a formal semantics, and the resulting policies are evaluated by means of a Java-based software tool

    Narrowband angle of arrival estimation exploiting graph topology and graph signals

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    Based on recent results of applying graph signal processing (GSP) to narrowband angle of arrival estimation for uniform linear arrays, we generalise the analysis to the case of arrays with elements placed arbitrarily in three dimensional space. We comment on the selection of the adjacency matrix, analyse how this new approach compares to the multiple signal classification (MUSIC) algorithm, and provide an efficient implementation. We demonstrate that the GSP approach can perform as well as the MUSIC algorithm in terms of accuracy and computational cost. Simulations indicate that the proposed GSP approach avoids the severe performance degradation with which MUSIC is associated at low signal to noise ratios

    Managing deadline miss ratio and sensor data freshness in real-time databases

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