Silicea Gastrointestinal Gel Improves Gastrointestinal Disorders: A Non-Controlled, Pilot Clinical Study

Aim. To investigate efficacy and tolerability of Silicea Gastrointestinal Gel in patients with gastrointestinal disorders. Methods. Open, prospective pivotal phase IV study with oral Silicea Gastrointestinal Gel over 6 weeks. Symptom score was part 1 of the Nepean Dyspepsia Index: 15 questions addressing intensity, frequency and impact of upper abdominal symptoms. 10 lower abdominal symptoms were asked analogously. A responder showed reduction of score of >50%. Results. 62 of 90 patients were evaluated per protocol. Upper and lower abdomen sum scores decreased already in the first three weeks (P < 0.001), which continued the following three weeks (P < 0.01). Mean symptom score for upper abdomen decreased from 52.2 ± 31.0 to 33.7 ± 28.7 (or by 35.4%; responder rate 37%); for lower from 39.6 ± 24.7 to 22.6 ± 21.7 (by 42.9%; responder rate 46%). Subgroups with diarrhea, IBS and GERD presented highest responder rates. 6% of patients reported adverse reactions with probable or possible relationship to the test product. Conclusions. Silicea Gastrointestinal Gel seems suitable beyond infectious acute gastrointestinal disorders. Responses are relevant for chronic functional disorders, but it remains unclear, how much of that might be placebo-effect. Controlled studies are recommended in gastrointestinal syndromes like IBS or GERD

Transitions Induced by the Discreteness of Molecules in a Small Autocatalytic System

Autocatalytic reaction system with a small number of molecules is studied numerically by stochastic particle simulations. A novel state due to fluctuation and discreteness in molecular numbers is found, characterized as extinction of molecule species alternately in the autocatalytic reaction loop. Phase transition to this state with the change of the system size and flow is studied, while a single-molecule switch of the molecule distributions is reported. Relevance of the results to intracellular processes are briefly discussed.Comment: 5 pages, 4 figure

A double parton scattering background to Higgs boson production at the LHC

The experimental capability of recognizing the presence of b quarks in complex hadronic final states has addressed the attention towards final states with b\bar{b} pairs for observing the production of the Higgs boson at the LHC, in the intermediate Higgs mass range.We point out that double parton scattering processes are going to represent a sizeable background to the process.Comment: 9 pages, 2 figure

Anomalous Higgs Couplings

We review the effects of new effective interactions on the Higgs boson phenomenology. New physics in the electroweak bosonic sector is expected to induce additional interactions between the Higgs doublet field and the electroweak gauge bosons leading to anomalous Higgs couplings as well as to anomalous gauge-boson self-interactions. Using a linearly realized $SU(2)_L \times U(1)_Y$ invariant effective Lagrangian to describe the bosonic sector of the Standard Model, we review the effects of the new effective interactions on the Higgs boson production rates and decay modes. We summarize the results from searches for the new Higgs signatures induced by the anomalous interactions in order to constrain the scale of new physics in particular at CERN LEP and Fermilab Te vatron colliders.Comment: 35 pages, latex using epsfig.sty psfig.sty and axodraw.sty, 16 postscript figure

Contact angles mediate equilibrium fractionation between soil water and water vapor

Soil water potential is a function of grain size, adhesion and cohesion energy. The mechanical equilibrium between the interfacial free energies between water-gas, water-solid and solid-gas, leads to a particular contact angle at the three phase boundary water-solid-gas. The contact angle of the solid-soil affects the water retention in soils. Contact angles &gt;0 lead to a shift of the water retention curve to simulating a coarser soil texture. Thus, a certain amount of water is stronger bound in a soil with a low contact angle compared to the same soil with a high contact angle. The relationship between the contact angle and the fractionation of water stable isotopes between soil water and water vapor has yet not been studied. We present a simple laboratory experiment with soil samples ranging from sand to silt to clay. Two subsamples were hydrophobized (or treated with) using dichlorodimethylsilane to produce different contact angles. Subsamples were transferred into Ziploc bags spiked with water of known isotopic composition and the headspace filled with dry air. After equilibration (at least 24h) the headspace was measured for its isotopic signature with a Laserspectrometer. Soil water potential was measured with a soil water potential meter and the contact angle determined with the Wilhelmy-plate-method (WPM). The working hypothesis is that the equilibrium between water and water vapor depends on the matric potential. Having the same pore and the same water content water repellency affects the soil water potential. Therefore the hydrophobized soil will change the equilibrium fractionation between water and water vapor. Hence, the contact angle between adsorbed water and water vapor is related to isotope effects

Window on Higgs Boson: Fourth Generation b′b^\prime Decays Revisited

Direct and indirect searches of the Higgs boson suggest that 113 GeV $\lesssim m_H \lesssim$ 170 GeV is likely. With the LEP era over and the Tevatron Run II search via $p\bar p \to WH+X$ arduous, we revisit a case where $WH$ or $ZH +$ jets could arise via strong $b^\prime\bar b^\prime$ pair production. In contrast to 10 years ago, the tight electroweak constraint on $t^\prime$--$b^\prime$ (hence $t^\prime$--$t$) splitting reduces FCNC $b^\prime\to bZ$, $bH$ rates, making $b^\prime\to cW$ naturally competitive. Such a "cocktail solution" is precisely the mix that could evade the CDF search for $b^\prime\to bZ$, and the $b^\prime$ may well be lurking below the top. In light of the Higgs program, this two-in-one strategy should be pursued.Comment: 4 pages, RevTex, 4 eps figures, One more figure, version to be published in Phys. Rev.

How primary care can contribute to good mental health in adults.

The need for support for good mental health is enormous. General support for good mental health is needed for 100% of the population, and at all stages of life, from early childhood to end of life. Focused support is needed for the 17.6% of adults who have a mental disorder at any time, including those who also have a mental health problem amongst the 30% who report having a long-term condition of some kind. All sectors of society and all parts of the NHS need to play their part. Primary care cannot do this on its own. This paper describes how primary care practitioners can help stimulate such a grand alliance for health, by operating at four different levels - as individual practitioners, as organisations, as geographic clusters of organisations and as policy-makers

Ultrafast modulation of the chemical potential in BaFe2_2As2_2 by coherent phonons

Time- and angle-resolved extreme ultraviolet photoemission spectroscopy is used to study the electronic structure dynamics in BaFe$_2$As$_2$ around the high-symmetry points $\Gamma$ and $M$. A global oscillation of the Fermi level at the frequency of the $A_{1g}$(As) phonon mode is observed. It is argued that this behavior reflects a modulation of the effective chemical potential in the photoexcited surface region that arises from the high sensitivity of the band structure near the Fermi level to the $A_{1g}$ phonon mode combined with a low electron diffusivity perpendicular to the layers. The results establish a novel way to tune the electronic properties of iron pnictides: coherent control of the effective chemical potential. The results further suggest that the equilibration time for the effective chemical potential needs to be considered in the ultrafast electronic structure dynamics of materials with weak interlayer coupling.Comment: 6 pages, 3 figure

The Reach of CERN LEP2 and Fermilab Tevatron Upgrades for Higgs Bosons in Supersymmetric Models

Luminosity upgrades of the Fermilab Tevatron pbar-p collider have been shown to allow experimental detection of a Standard Model (SM) Higgs boson up to $m_{H_{SM}}\sim 120$ GeV via $WH_{SM} \to \ell\nu b\bar{b}$ events. This limit nearly saturates the parameter space for many models of weak scale supersymmetry (SUSY) with a minimal particle content. It is therefore interesting to examine the SUSY Higgs reach of future Tevatron experiments. Contours are presented of Higgs boson reach for CERN LEP2 and Tevatron luminosity upgrades for three models of weak scale SUSY: the Minimal Supersymmetric Standard Model (MSSM), the minimal Supergravity model (mSUGRA) and a simple Gauge Mediated SUSY Breaking Model (GMSB). In each case we find a substantial gain in reach at the Tevatron with integrated luminosity increasing from 10 fb^{-1} to 25-30 fb^{-1}. With the larger integrated luminosity, a Higgs search at the Tevatron should be able to probe essentially the entire parameter space of these models. While a discovery would be very exciting, a negative result would severely constrain our ideas about how weak scale supersymmetry is realized.Comment: 12 pages + 7 figures. Uses REVTEX and epsf macros. Several references added, stated value of A-parameters corrected, note added reguarding sgn(mu) dependence in MSSM case. To appear in Physical Review