LEADERSHIP EMPOWERMENT BEHAVIOUR, WORK ENGAGEMENT AND TURNOVER INTENTION: THE ROLE OF PSYCHOLOGICAL EMPOWERMENT

Research purpose: The purpose of this study was to investigate the relationship between leadership empowerment behavior, psychological empowerment, work engagement and turnover intention. The study further investigated whether psychological empowerment mediates the relationship between leadership empowerment behavior and turnover intention and work engagement respectively.Research design, approach and method: A cross-sectional survey design was used with a convenience sample (N = 322). Confirmatory factor analysis was used to test whether the measures of the constructs were consistent with the understanding of the nature of the constructs and to test whether the data fitted the hypothesized measurement model. Structural Equation Modeling (SEM) was used to examine the structural relationships between the constructs.Measuring instruments: The Leader Empowering Behavior Questionnaire, Measuring Empowerment, Work Engagement and Turnover Intention scales were administered.Main findings: The results showed significant positive relationships between leadership empowerment behavior, psychological empowerment, work engagement and a negative correlation with turnover intention. Leadership empowerment behavior affected work engagement through psychological empowerment.Practical implications: It is recommended that leadership discussions, training programs and individual coaching about leadership empowering behavior takes place

Neuropathic itch

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Brachioradial pruritus: a trigger for generalization of itch

Brachioradial pruritus (BRP) is a form of neuropathic itch characterized by localized itching, burning, stinging, and tingling sensations on the dorsolateral aspect of the forearm and upper arms. Herein we present a case series of 8 patients with BRP-triggered generalized pruritus

Multifocal White Matter Lesions Associated with the D313Y Mutation of the α-Galactosidase A Gene

<div><p>White matter lesions (WML) are clinically relevant since they are associated with strokes, cognitive decline, depression, or epilepsy, but the underlying etiology in young adults without classical risk factors still remains elusive. Our aim was to elucidate the possible clinical diagnosis and mechanisms leading to WML in patients carrying the D313Y mutation in the α-galactosidase A (GLA) gene, a mutation that was formerly described as nonpathogenic. Pathogenic GLA mutations cause Fabry disease, a vascular endothelial glycosphingolipid storage disease typically presenting with a symptom complex of renal, cardiac, and cerebrovascular manifestations. We performed in-depths clinical, biochemical and genetic examinations as well as advanced magnetic resonance imaging analyses in a pedigree with the genetically determined GLA mutation D313Y. We detected exclusive neurologic manifestations of the central nervous system of the “pseudo”-deficient D313Y mutation leading to manifest WML in 7 affected adult family members. Furthermore, two family members that do not carry the mutation showed no WML. The D313Y mutation resulted in a normal GLA enzyme activity in leukocytes and severely decreased activities in plasma. In conclusion, our results provide evidence that GLA D313Y is potentially involved in neural damage with significant WML, demonstrating the necessity of evaluating patients carrying D313Y more thoroughly. D313Y might broaden the spectrum of hereditary small artery diseases of the brain, which preferably occur in young adults without classical risk factors. In view of the existing causal therapy regime, D313Y should be more specifically taken into account in these patients.</p> </div

The Effect of Crisaborole Ointment, 2%, on Pruritus in Patients with Atopic Dermatitis: An Extended Analysis

Abstract Not Available</jats:p