4,318 research outputs found
Femtosecond x-ray absorption spectroscopy of spin and orbital angular momentum in photoexcited Ni films during ultrafast demagnetization
We follow for the first time the evolution of the spin and orbital angular
momentum of a thin Ni film during ultrafast demagnetization, by means of x-ray
magnetic circular dichroism. Both components decrease with a 130 +/- 40 fs time
constant upon excitation with a femtosecond laser pulse. Additional x-ray
absorption measurements reveal an increase in the spin-orbit interaction by 6
+/- 2 % during this process. This is the experimental demonstration quantifying
the importance of spin-orbit mediated processes during the demagnetization
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Levothyroxine effects on depressive symptoms and limbic glucose metabolism in bipolar disorder: a randomized, placebo-controlled positron emission tomography study.
Adding supraphysiologic doses of levothyroxine (L-T4) to standard treatment for bipolar depression shows promise, but the mechanisms underlying clinical improvement are unknown. In a previous pilot study, L-T4 treatment reduced depression scores and activity within the anterior limbic network. Here we extended this work in a randomized, double-blind, placebo-controlled study of patients with bipolar depression. Cerebral glucose metabolism was assessed with positron emission tomography and [F-18]fluorodeoxyglucose before and after 6 weeks of treatment with L-T4 (n=15) or placebo (n=10) in 12 volumes of interest (VOIs): the bilateral thalamus, amygdala, hippocampus, dorsal striatum and ventral striatum, and midline cerebellar vermis and subgenual cingulate cortex. Radioactivity in the VOIs, normalized to whole-brain radioactivity was taken as a surrogate index of glucose metabolism, and markers of thyroid function were assayed. Changes in brain activity and their association with clinical response were assessed using statistical parametric mapping. Adjunctive L-T4 treatment produced a significant decline in depression scores during the 6-week treatment. In patients treated with L-T4, we found a significant decrease in regional activity at P<0.05 after Bonferroni correction in the left thalamus, right amygdala, right hippocampus, left ventral striatum and the right dorsal striatum. Decreases in the left thalamus, left dorsal striatum and the subgenual cingulate were correlated with a reduction in depression scores (P<0.05 after Bonferroni correction). Placebo treatment was associated with a significant decrease in activity only in the right amygdala, and no region had a change in activity that was correlated with change in depression scores. The groups differed significantly in the relationship between the changes in depression scores and in activity in the thalamus bilaterally and the left ventral striatum. The findings provide evidence that administration of supraphysiologic thyroid hormone improves depressive symptoms in patients with bipolar disorder by modulating function in components of the anterior limbic network
Solar System Objects in the ISOPHOT 170 micron Serendipity Survey
The ISOPHOT Serendipity Survey (ISOSS) covered approximately 15 % of the sky
at a wavelength of 170 micron while the ISO satellite was slewing from one
target to the next. By chance ISOSS slews went over many solar system objects
(SSOs). We identified the comets, asteroids and planets in the slews through a
fast and effective search procedure based on N-body ephemeris and flux
estimates. The detections were analysed from a calibration and scientific point
of view. Through the measurements of the well-known asteroids Ceres, Pallas,
Juno and Vesta and the planets Uranus and Neptune it was possible to improve
the photometric calibration of ISOSS and to extend it to higher flux regimes.
We were also able to establish calibration schemes for the important slew end
data. For the other asteroids we derived radiometric diameters and albedos
through a recent thermophysical model. The scientific results are discussed in
the context of our current knowledge of size, shape and albedos, derived from
IRAS observations, occultation measurements and lightcurve inversion
techniques. In all cases where IRAS observations were available we confirm the
derived diameters and albedos. For the five asteroids without IRAS detections
only one was clearly detected and the radiometric results agreed with sizes
given by occultation and HST observations. Four different comets have clearly
been detected at 170 micron and two have marginal detections. The observational
results are presented to be used by thermal comet models in the future. The
nine ISOSS slews over Hale-Bopp revealed extended and asymmetric structures
related to the dust tail. We attribute the enhanced emission in post-perihelion
observations to large particles around the nucleus. The signal patterns are
indicative of a concentration of the particles in trail direction.Comment: 15 pages, 6 figures, 6 tables; Accepted for publication in Astronomy
and Astrophysic
The effect of e-learning on the quality of orthodontic appliances
Purpose: The effect of e-learning on practical skills in medicine has not yet been thoroughly investigated. Today’s multimedia learning environment and access to e-books provide students with more knowledge than ever before. The aim of this study is to evaluate the effect of online demonstrations concerning the quality of orthodontic appliances manufactured by undergraduate dental students. Materials and methods: The study design was a parallel-group randomized clinical trial. Fifty-four participants were randomly assigned to one of the three groups: 1) conventional lectures, 2) conventional lectures plus written online material, and 3) access to resources of groups one and two plus access to online video material. Three orthodontic appliances (Schwarz Plate, U-Bow Activator, and Fränkel Regulator) were manufactured during the course and scored by two independent raters blinded to the participants. A 15-point scale index was used to evaluate the outcome quality of the appliances. Results: In general, no significant differences were found between the groups. Concerning the appliances, the Schwarz Plate obtained the highest scores, whereas the Fränkel Regulator had the lowest scores; however, these results were independent of the groups. Females showed better outcome scores than males in groups two and three, but the difference was insignificant. Age of the participants also had no significant effect. Conclusion: The offer that students could use additional time and course-independent e-learning resources did not increase the outcome quality of the orthodontic appliances. The advantages of e-learning observed in the theoretical fields of medicine were not achieved in the educational procedures for manual skills. Factors other than e-learning may have a higher impact on manual skills, and this should be investigated in further studies
The relevance of ERTS-1 data to the state of Ohio
There are no author-identified significant results in this report
Imperfect Homoclinic Bifurcations
Experimental observations of an almost symmetric electronic circuit show
complicated sequences of bifurcations. These results are discussed in the light
of a theory of imperfect global bifurcations. It is shown that much of the
dynamics observed in the circuit can be understood by reference to imperfect
homoclinic bifurcations without constructing an explicit mathematical model of
the system.Comment: 8 pages, 11 figures, submitted to PR
Insights on Water Interaction at the Interface of Nitrogen Functionalized Hydrothermal Carbons
Hydrothermal carbon (HTC) derived from biomass is a class of cost-efficient, eco-friendly functional carbon materials with various potential applications. In this work, solid-state nuclear magnetic resonance (NMR), longitudinal (T1) relaxation time and diffusion NMR were employed to investigate the structure and water dynamics for HTC and nitrogen-functionalized hydrothermal carbon (N-HTC) samples ((N)-HTC). Results showed that the presence of N-functional groups influences the water interaction with (N)-HTC more strongly than surface area, pore size distribution or oxygenated functional groups. Furthermore, the degree of water interaction can be tuned by adjusting the synthesis temperature and the precursor ratio. Water motion was more strongly inhibited in N-HTC than in N-free HTC, thereby suggesting the existence of a differently structured hydration shell around N-HTC particles. In addition, the diffusion data of water in the N-HTC material shows two components that do not exchange on the time scale of the experiment (tens of milliseconds), indicating a significant fraction of slow mobile water that exists inside the structure of N-HTC. 1H–2H isotope exchange and cross-polarization NMR results show this internal water only in a near-surface layer of the N-HTC particles. Based on these findings, a model for water interaction with (N)-HTC particles is proposed
Early treatment of posterior crossbite - a randomised clinical trial
Background: The aim of this randomised clinical trial was to assess the effect of early orthodontic treatment in contrast to normal growth effects for functional unilateral posterior crossbite in the late deciduous and early mixed dentition by means of three-dimensional digital model analysis.
Methods: This randomised clinical trial was assessed to analyse the orthodontic treatment effects for patients with functional unilateral posterior crossbite in the late deciduous and early mixed dentition using a two-step procedure: initial maxillary expansion followed by a U-bow activator therapy. In the treatment group 31 patients and in the control group 35 patients with a mean age of 7.3 years (SD 2.1) were monitored. The time between the initial assessment (T1) and the follow-up (T2) was one year. The orthodontic analysis was done by a three-dimensional digital model analysis. Using the ‘Digimodel’ software, the orthodontic measurements in the maxilla and mandible and for the midline deviation, the overjet and overbite were recorded.
Results: Significant differences between the control and the therapy group at T2 were detected for the anterior, median and posterior transversal dimensions of the maxilla, the palatal depth, the palatal base arch length, the maxillary arch length and inclination, the midline deviation, the overjet and the overbite.
Conclusions: Orthodontic treatment of a functional unilateral posterior crossbite with a bonded maxillary expansion device followed by U-bow activator therapy in the late deciduous and early mixed dentition is an effective therapeutic method, as evidenced by the results of this RCT. It leads to three-dimensional therapeutically induced maxillary growth effects. Dental occlusion is significantly improved, and the prognosis for normal craniofacial growth is enhanced
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