O neo-humanismo chinês: um novo paradigma internacional e jurídico nas relações internacionais China-América Latina

In this article we propose the concept of Chinese neohumanism to interpret the current Chinese internal reform process and China's international positioning. Although similar currents and ideas had already emerged in the history of China, the analysis will focus on the innovative aspects of the current Chinese reformist trajectory. In fact, it is argued that elements of “neo-humanist” thought in China have revealed their influence on international law and relations. The drafting of the new Civil Code of the People's Republic of China, approved in May 2020, and the construction of new theories and practices of international relations, especially the adoption of the concept of “Community of Shared Future for Mankind”, offer many contents to interpret through a circular thought the construction of a system that stands as a people-centered approach (“people-centrism”), generating a new humanism. Likewise, the analysis aims to find the elements of the Chinese humanist process in international relations with Latin America.  En este artículo proponemos el concepto de neohumanismo chino para interpretar el actual proceso de reformas internas y el posicionamiento internacional de China. Aunque ya habían surgido corrientes similares a esta idea en la historia de China, el análisis se centrará en los aspectos innovadores de la actual trayectoria reformista china. De hecho, se sostiene que los elementos del pensamiento “neo-humanista” en China  han desvelado su influencia en el derecho y las relaciones internacionales. La redacción del nuevo Código Civil de la República Popular China, aprobado en mayo 2020, y la construcción de nuevas teorías y prácticas de las relaciones internacionales, sobretodo la adopción del concepto de “comunidad de destino compartido para la humanidad”, ofrecen muchas ideas para interpretar a través de un pensamiento circular la construcción de un sistema que se erige como un enfoque centrado en las personas (“pueblo-centrismo”), generando un nuevo humanismo. Asimismo, el análisis busca encontrar los elementos del proceso humanista chino en las relaciones internacionales con América Latina.Neste artigo propomos o conceito de neo-humanismo chinês para interpretar o processo atual de reformas internas e o posicionamento internacional da China.  Embora já tivessem surgido correntes similares a esta ideia na história da China, a análise será centrada nos aspectos inovadores da atual trajetória reformista chinesa. De fato, se sustem que os elementos do pensamento “neo-humanista” na China tem revelado sua influência no direito e nas relações internacionais. A redação do novo Código Civil da República Popular da China, aprovado em maio de 2020, e a construção de novas teorias e práticas de relações internacionais, sobretudo com a adoção do conceito de “comunidade de destino compartilhado para a humanidade”, oferecem muitas ideias para se interpretar, através de um pensamento circular, a construção de um sistema  que emerge centrado nas pessoas (“povo-centrismo”), gerando um novo humanismo. Desta forma, a análise busca encontrar os elementos do processo humanista chinês nas relações internacionais com a América Latina

La respuesta italiana frente al COVID-19 y la necesidad de la cooperación internacional

The article proposes a first approximation to the international cooperation response against the novel coronavirus disease 2019 (COVID-19) pandemic. In particular, the paper aims to analyze the two fundamental strategies against the virus, with a focus on the Italian reaction and its consequences on European cooperation. The pandemic has accelerated some conflicts and claimed deeper international cooperation on health and the attempt to create a "community of shared health" for mankind.El artículo propone una primera aproximación a la respuesta de cooperación internacional contra la nueva pandemia de la enfermedad por coronavirus 2019 (COVID-19). En particular, el documento tiene como objetivo analizar las dos estrategias fundamentales contra el virus, con un enfoque en la reacción italiana y sus consecuencias en la cooperación europea. La pandemia ha acelerado algunos conflictos y ha reclamado una cooperación internacional más profunda en materia de salud y el intento de crear una "comunidad de salud compartida" para la humanidad

La construcción de una Comunidad de destino compartido para la humanidad: análisis multidimensional de un nuevo paradigma internacional

El presente trabajo se propone reconstruir e interpretar la noción de Comunidad de destino compartido para la humanidad (人类命运共同体) presentada por Xi Jinping en 2011. Este concepto ha adquirido gran protagonismo en los documentos y discursos oficiales del gobierno chino, vinculándose con la propuesta de configurar relaciones internacionales de nuevo tipo, una mirada de la comunidad internacional desde un nuevo humanismo, la recuperación del Espíritu de Bandung y la reivindicación de la Cooperación Sur-Sur. La noción de “Comunidad de destino” se enmarca en un debate más general sobre la reestructuración de las relaciones de poder mundial, expresada en un creciente protagonismo del Asia Pacífico y de la RP China. Este proceso trae aparejado la posibilidad del rediseño de las instituciones de gobernanza global y de los principios y valores que deberían regir las instituciones mundiales. Comprender la idea de “Comunidad de destino compartido” nos permite interpretar la propuesta china para el nuevo ordenamiento mundial que se está gestando en la actualidad.Fil: Schulz, Juan Sebastián. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones en Humanidades y Ciencias Sociales. Universidad Nacional de La Plata. Facultad de Humanidades y Ciencias de la Educación. Instituto de Investigaciones en Humanidades y Ciencias Sociales; ArgentinaFil: Staiano, Maria Francesca. Universidad Nacional de La Plata. Facultad de Ciencias Jurídicas y Sociales. Instituto de Relaciones Internacionales; Argentin

Selected papers from the 15th and 16th international conference on Computational Intelligence Methods for Bioinformatics and Biostatistics

Funding Information: CIBB 2019 was held at the Department of Human and Social Sciences of the University of Bergamo, Italy, from the 4th to the 6th of September 2019 []. The organization of this edition of CIBB was supported by the Department of Informatics, Systems and Communication of the University of Milano-Bicocca, Italy, and by the Institute of Biomedical Technologies of the National Research Council, Italy. Besides the papers focused on computational intelligence methods applied to open problems of bioinformatics and biostatistics, the works submitted to CIBB 2019 dealt with algebraic and computational methods to study RNA behaviour, intelligence methods for molecular characterization and dynamics in translational medicine, modeling and simulation methods for computational biology and systems medicine, and machine learning in healthcare informatics and medical biology. A supplement published in BMC Medical Informatics and Decision Making journal [] collected three revised and extended papers focused on the latter topic.publishersversionpublishe

Social media use to improve communication on children and adolescent’s health: the role of the Italian Paediatric Society influencers

Background Fake news on children’s and adolescent health are spreading. Internet availability and decreasing costs of media devices are contributing to an easy access to technology by families. Public health organizations are working to contrast misinformation and promote scientific communication. In this context, a new form of communication is emerging social media influencers. Aim of this study is to evaluate the role of paediatric influencers (PI) in communicating information about children and adolescents’ health. Materials and methods A group of PI was enrolled from December 2019 to January 2020 by a scientific commission nominated by the Italian Paediatric Society (SIP). PI were asked to share Facebook messages from the official page of the SIP to their own network. Social media tools have been evaluated across 12 months, from July 28, 2019, to July 11, 2020. For the purposes of clarity, we schematically divided the study period as follows: the period of PIs activity (January 6, 2020, to July 11, 2020) and the period when PIs were not yet active (July 28, 2019, to January 4, 2020). Information on Facebook page (lifetime total likes, daily new likes, daily page engaged, daily total reach) and on published post (lifetime post total reach, lifetime post organic reach, lifetime engaged users) were evaluated. Results A significant increase in Facebook daily new likes, page engagement and total reach, as well as in lifetime post total and organic reach was evidenced. As for PI, they reported a positive experience in most cases. Discussion In the digital era, communication strategies are becoming more important, so that the scientific community has to be actively involved in social media communication. Our pilot study demonstrated that the recruitment of paediatric influencers has increased communication and interaction of the SIP Facebook page. Conclusion Our study shows the potential role of influencers: spreading health messages via PI seems to be a successful strategy to promote correct communication about children’s and adolescents’ health

Amino acid transport in thermophiles: characterization of an arginine-binding protein in Thermotoga maritima. 2. Molecular organization and structural stability

ABC transport systems provide selective passage of metabolites across cell membranes and typically require the presence of a soluble binding protein with high specificity to a specific ligand. In addition to their primary role in nutrient gathering, the binding proteins associated with bacterial transport systems have been studied for their potential to serve as design scaffolds for the development of fluorescent protein biosensors. In this work, we used Fourier transform infrared spectroscopy and molecular dynamics simulations to investigate the physicochemical properties of a hyperthermophilic binding protein from Thermotoga maritima. We demonstrated preferential binding for the polar amino acid arginine and experimentally monitored the significant stabilization achieved upon binding of ligand to protein. The effect of temperature, pH, and detergent was also studied to provide a more complete picture of the protein dynamics. A protein structure model was obtained and molecular dynamic experiments were performed to investigate and couple the spectroscope observations with specific secondary structural elements. The data determined the presence of a buried ẞ-sheet providing significant stability to the protein under all conditions investigated. The specific amino acid residues responsible for arginine binding were also identified. Our data on dynamics and stability will contribute to our understanding bacterial binding protein family members and their potential biotechnological applications

Amino acid transport in thermophiles: characterization of an arginine-binding protein in Thermotoga maritima. 2. Molecular organization and structural stability

ABC transport systems provide selective passage of metabolites across cell membranes and typically require the presence of a soluble binding protein with high specificity to a specific ligand. In addition to their primary role in nutrient gathering, the binding proteins associated with bacterial transport systems have been studied for their potential to serve as design scaffolds for the development of fluorescent protein biosensors. In this work, we used Fourier transform infrared spectroscopy and molecular dynamics simulations to investigate the physicochemical properties of a hyperthermophilic binding protein from Thermotoga maritima. We demonstrated preferential binding for the polar amino acid arginine and experimentally monitored the significant stabilization achieved upon binding of ligand to protein. The effect of temperature, pH, and detergent was also studied to provide a more complete picture of the protein dynamics. A protein structure model was obtained and molecular dynamic experiments were performed to investigate and couple the spectroscope observations with specific secondary structural elements. The data determined the presence of a buried ẞ-sheet providing significant stability to the protein under all conditions investigated. The specific amino acid residues responsible for arginine binding were also identified. Our data on dynamics and stability will contribute to our understanding bacterial binding protein family members and their potential biotechnological applications

Association of USF1 and APOA5 polymorphisms with familial combined hyperlipidemia in an Italian population.

Familial combined hyperlipidemia (FCH) is a polygenic and multifactorial disease characterized by a variable phenotype showing increased levels of triglycerides and/or cholesterol. The aim of this study was to identify single nucleotides (SNPs) in lipid-related genes associated with FCH. METHODS AND RESULTS: Twenty SNPs in lipid-related genes were studied in 142 control subjects and 165 FCH patients after excluding patients with mutations in the LDLR gene and patients with the E2/E2 genotype of APOE. In particular, we studied the 9996G > A (rs2073658) and 11235C > T (rs3737787) variants in the Upstream Stimulatory Factor 1 gene (USF1), and the -1131T > C (rs662799) and S19W (rs3135506) variants in the Apolipoprotein A-V gene (APOA5). We found that the frequencies of these variants differed between patients and controls and that are associated with different lipid profiles. At multivariate logistic regression SNP S19W in APOA5 remained significantly associated with FCH independently of age, sex, BMI, cholesterol and triglycerides. CONCLUSIONS: Our results show that the USF1 and APOA5 polymorphisms are associated with FCH and that the S19W SNP in the APOA5 gene is associated to the disease independently of total cholesterol, triglycerides and BMI. However, more extensive studies including other SNPs such as rs2516839 in USF1, are required