Salivary Alterations in Rats with Experimental Chronic Kidney Disease

Objective This study aimed to analyze changes in saliva composition and salivary secretion process of rats with chronic kidney disease induced by 5/6 nephrectomy to set the foundation for salivary studies related to CKD. Methods CKD was induced in Wistar rats via 5/6 nephrectomy. Blood and saliva samples were collected from Control, Sham and CKD groups at 8 and 12 weeks after the surgery. Salivation was stimulated via intraperitoneal injections of pilocarpine (1.0 mg/Kg body weight) or isoproterenol (5.0 mg/Kg body weight). Saliva was collected and immediately stored at -80 degrees C until analysis. The salivary flow rate, total protein, amylase and peroxidase activities, and urea concentrations were measured. The blood urea nitrogen (BUN) and serum creatinine concentrations were also evaluated. Results Increases in BUN and serum creatinine concentrations were observed in the CKD groups. Amylase activity was significantly reduced in response to both stimuli in the CKD groups at 8 weeks and increased in the CKD groups at 12 weeks in response to isoproterenol stimulus. The peroxidase activities of the CKD groups were significantly reduced in response to isoproterenol stimulation and were increased at 12 weeks in response to pilocarpine stimulation. Salivary urea was significantly increased in the CKD groups at 8 weeks in response to the isoproterenol stimuli and at 12 weeks in response to both salivary agonists. Conclusions The pattern of alterations observed in this experimental model is similar to those observed in patients and clearly demonstrates the viability of 5/6 nephrectomy as an experimental model in future studies to understand the alterations in salivary compositions and in salivary glands that are elicited by CKD.FAPESP (the Research Council for the State of Sao Paulo)Univ Sao Paulo, Dept Biomat & Biol Oral, Fac Odontol, Sao Paulo, BrazilEscola Paulista Med UNIFESP, Dept Fisiol, Sao Paulo, BrazilEscola Paulista Med UNIFESP, Dept Fisiol, Sao Paulo, BrazilFAPESP: 2013-18609-1Web of Scienc

INFLUÊNCIA DOS FATORES SOCIOECONÔMICOS NO DESENVOLVIMENTO DO PESO EM ESCOLARES DE FEIRA DE SANTANA-BA

Nas últimas décadas, importantes mudanças econômicas, sociais e tecnológicas propiciaram alterações no perfil epidemiológico das doenças nas sociedades modernas. Nesse cenário, variações nos indicadores nutricionais favoreceram um aumento significativo da obesidade, observado tanto em adultos quanto em crianças. Dados recentes do NCD Risk Factor Collaboration mostram que essa condição afeta cerca de 671 milhões de adultos no mundo, o que representa aproximadamente 10% da população mundial (NCD-RISC, 2017)

Tracing the Use of Communication Technology in Higher Education: a literature review

Communication Technologies are used in Higher Education Institutions worldwide, producing changes in the design of teaching and learning practices, giving rise to learning paradigms such as e-learning, b-learning, m-learning and cloud learning. Research embraces different perspectives, emphasizing that Internet and Communication Technologies use is not potentiating innovation or disruptiveness of more traditional forms of education, while another perspective argues that there is disruptiveness that is becoming ever more powerful, promoting changes in the roles and way teachers and students work. The present review suggests that web 2.0 technologies has promoted new forms of communication, interaction and sharing between users and content in formal education settings. Furthermore, the realization of how vast and disperse the body of literature is, concerning the use of Communication Technologies in HE, revealed as significant the main goals of the project “Portuguese Public Higher Education Use of Communication Technologies”, that aims to characterize Portuguese higher education institutions according to their use and best practices, disseminating the information obtained through an online visualization information tool. The ultimate goal of the project is to contribute towards making valuable and up-to-date information available to Higher Education Institutions and users, facilitating and potentiating research in the area

Development and validation of a stability indicating HPLC method to determine diltiazem hydrochloride in tablets and compounded capsules

A stability indicating HPLC method to determine diltiazem hydrochloride (DTZ) in tablets and compounded capsules was developed and validated according to Brazilian and the International Conference on Harmonization (ICH) guidelines. The separation was carried out on a Purospher Star® C18 (150 x 4.6 mm i.d., 5 µm particle size, Merck Millipore) analytical column. The mobile phase consisted of a 0.05% (v/v) trifluoroacetic acid aqueous solution and a 0.05% trifluoroacetic acid methanolic solution (44:56, v/v). The flow rate was 1.0 mL.min-1 with a run time of 14 minutes. The detection of DTZ and degradation products (DP) was performed at 240 nm, using a diode array detector. The method proved to be linear, precise, accurate, selective, and robust, and was adequate for stability studies and routine quality control analyses of DTZ in tablets and compounded capsules

Proporcionando atualizações em nutrição para a comunidade - 53955031

Trabalho apresentado no 31º SEURS - Seminário de Extensão Universitária da Região Sul, realizado em Florianópolis, SC, no período de 04 a 07 de agosto de 2013 - Universidade Federal de Santa Catarina.A nutrição desportiva visa orientar para que a alimentação e a hidratação realizadas antes, durante e após as modalidades desportivas sejam de boas escolhas, favorecendo o bem-estar do indivíduo. Os escolares que apresentam melhor rendimento desportivo são aqueles que têm garantidos, em seus organismos, adequados suprimentos de energia, nutrientes e, de líquidos corporais, contribuindo para com o desenvolvimento de jogos escolares e as modalidades em aulas de educação física, que requerem esforço físico. É usual que muitas crianças e adolescentes não realizem o desjejum antes de irem à escola e, com isso, seu rendimento na atividade desportiva ficará aquém de seu potencial, caso não ingiram alimentos e tomem líquidos antes das aulas de educação física. O mesmo se aplica em situações de preparo de alunos para campeonatos estudantis, nos turnos inversos ao horário de aulas. A Nutrição se dedica a orientar para que as referidas escolhas alimentícias por escolares sejam saudáveis, apropriadas ao processo digestório do momento, promovam o aporte energético e de hidratação requeridos ao desporto, antes, durante e após a atividade física

Tracing the Emmerging Use of Communication Technologies in Higher Education

Communication Technologies being used in Higher Education Institutions worldwide are producing changes in the design of teaching and learning practices, giving rise to learning paradigms such as elearning, b-learning and m-learning. Research embraces different perspectives on how the use of Internet and Communication Technologies potentiate innovation and disruptiveness of more traditional forms of education, as well as promotion of changes in the way teachers and students work and in the roles they adopt. The present review suggests that web 2.0 technologies has promoted new forms of communication, interaction and sharing between users and content in formal education settings. Furthermore, the realization of how vast and disperse the body of literature is, revealed as significant the main goals of the project “Portuguese Public Higher Education Use of Communication Technologies”, that aims to characterize Portuguese higher education institutions according to their use and best practices, disseminating the information obtained through an online information visualization tool. The ultimate goal of the project is to contribute towards making valuable and up-to-date information available to Higher Education Institutions and users, facilitating and potentiating research in the area

Sustainable citizen decision-making:Impact of the cost-of-living crisis on the energy and circular economy transitions in urban Scotland

The present report is the outcome of a research project commissioned by Zero Waste Scotland and carried out by the Just Transition Hub (JTH), University of Dundee, with the objective of understanding the ways in which the cost-of-living crisis has affected the attitudes and behaviours of individuals and communities towards a transition to a low-carbon economy in Scotland. We define the transition as encompassing both energy transition and the transition to a circular economy, so in this report the word “transition(s)” means both the referred transitions. We define the scope of “justice” to cover three dimensions – distributive, recognition and procedural. Briefly, distributive justice concerns the ideal of a fair share of the benefits and costs of the transition among different communities and stakeholders. Recognition justice respects the proper acknowledgement of marginalised individuals and communities who may be living in deprived urban areas. Procedural justice respects inclusion and effective participation of all, including marginalised actors, in public debate and decision-making. The study involved a literature review in narrative form (chapter 2) and a smallscale exploratory study (chapters 3 and 4), using a multi-strategy approach that included seven individual semi-structured expert interviews, four semi-structured citizen/consumer focus groups and one semi-structured expert focus group. Both the literature review and the empirical research adopted a thematic analysis approach, with clear research objectives identified in a standardised analysis framework. The present research is part of a broader series of investigations commissioned by Zero Waste Scotland to understand circular economy perspectives and sustainable decision-making in times of crises to help inform Zero Waste Scotland’s communication, engagement and further research for a just transition. The present study is complemented by parallel research being conducted by the University of Highlands and Islands with a focus on rural communities

SOLAR ENERGY AND ITS GLOBAL INVESTMENTS

Este trabalho teve por objetivo analisar as pesquisas de energia solar em escala global nos últimos cinco anos a fim de identificar as formas de aplicação dessa fonte de energia e quais países estão participando das pesquisas na área solar. Neste contexto Foram analisadas as publicações sobre energia solar dos últimos cinco anos (2010 – 2015) de revistas científicas voltadas a temática de energias renováveis, sendo adotado o Fator de Impacto (FI) como critério de seleção. Os artigos foram analisados a nível de resumo para um universo amostral de mais de 350 publicações, das quais o índice do FI variou de 3 a 15. Os resultados mostram que os países com maior número de publicações na área de energia solar no mundo foram Índia, China, Espanha, Malásia e Estados Unidos, totalizando mais da metade das pesquisas mundiais. A energia solar térmica teve maior participação nas pesquisas e o ano de 2014 o maior número de publicações em relação a energia solar no mundo