Investigations of the Mars Upper Atmosphere with ExoMars Trace Gas Orbiter

The Martian mesosphere and thermosphere, the region above about 60 km, is not the primary target of the ExoMars 2016 mission but its Trace Gas Orbiter (TGO) can explore it and address many interesting issues, either in-situ during the aerobraking period or remotely during the regular mission. In the aerobraking phase TGO peeks into thermospheric densities and temperatures, in a broad range of latitudes and during a long continuous period. TGO carries two instruments designed for the detection of trace species, NOMAD and ACS, which will use the solar occultation technique. Their regular sounding at the terminator up to very high altitudes in many different molecular bands will represent the first time that an extensive and precise dataset of densities and hopefully temperatures are obtained at those altitudes and local times on Mars. But there are additional capabilities in TGO for studying the upper atmosphere of Mars, and we review them briefly. Our simulations suggest that airglow emissions from the UV to the IR might be observed outside the terminator. If eventually confirmed from orbit, they would supply new information about atmospheric dynamics and variability. However, their optimal exploitation requires a special spacecraft pointing, currently not considered in the regular operations but feasible in our opinion. We discuss the synergy between the TGO instruments, specially the wide spectral range achieved by combining them. We also encourage coordinated operations with other Mars-observing missions capable of supplying simultaneous measurements of its upper atmosphere

The Fresnel interferometric imager

International audienceThe Fresnel interferometric imager is a new kind of high angular resolution space instrument for the UV domain, and the related astrophysical targets. This optical concept is meant to allow larger and lighter apertures in space than solid state optics. It yields high dynamic range images and same resolution as that of a solid aperture of the same size. The long focal lengths of the Fresnel imager (a few kilometers) require operation by two-vessel formation flying in space. The first vessel holds a large and thin opaque foil punched with thousands of holes: the interferometric array, the second vessel holds the focal instrumentation. This Fresnel imager has been designed for mapping high contrast stellar environments: dust disks, close companions and (we hope) exoplanets. Compact objects such as large stellar photospheres may be imaged with array sizes of a few meters in the UV. Larger and more complex fields can also be imaged, although with a lesser dynamic range, such as small fields on galactic clouds or extragalactic fields, or in an other domain: small solar system bodies. We present the first images obtained on artificial sources with an 8 cm laboratory testbed array having 26680 apertures, the measured dynamic range of these images and their diffraction limited angular resolution. A 3 m class probatory space mission will be studied and follow a validation path, It has been submitted as a proposal to the ESA Cosmic Vision program

Interference between nanoparticles and metal homeostasis

International audienceThe TiO2 nanoparticles (NPs) are now produced abundantly and widely used in a variety of consumer products. Due to the important increase in the production of TiO2-NPs, potential widespread exposure of humans and environment may occur during both the manufacturing process and final use. Therefore, the potential toxicity of TiO2-NPs on human health and environment has attracted particular attention. Unfortunately, the results of the large number of studies on the toxicity of TiO2-NPs differ significantly, mainly due to an incomplete characterization of the used nanomaterials in terms of size, shape and crystalline structure and to their unknown state of agglomeration/aggregation. The purpose of our project entitled NanoBioMet is to investigate if interferences between nanoparticles and metal homeostasis could be observed and to study the toxicity mechanisms of TiO2-NPs with well-characterized physicochemical parameters, using proteomic and molecular approaches. A perturbation of metal homeostasis will be evaluated upon TiO2-NPs exposure which could generate reactive oxygen species (ROS) production. Moreover, oxidative stress consequences such as DNA damage and lipid peroxidation will be studied. The toxicity of TiO2-NPs of different sizes and crystalline structures will be evaluated both in prokaryotic (E. coli) and eukaryotic cells (A549 human pneumocytes, macrophages, and hepatocytes). First results of the project will be presented concerning the dispersion of TiO2-NPs in bacterial medium, proteomic studies on total extracts of macrophages and genotoxicity on pneumocytes