Abcès pulmonaires à Salmonella enteritidis chez un patient infecté par le virus de l’immunodéficience humaine

Les pathologies respiratoires infectieuses restent la complication la plus fréquente de l’infection par le virus de l’immunodéficience humaine (VIH) quelle que soit l’importance de l’immunodépression. Les salmonelloses de l’adulte surviennent rarement chez le sujet sain dans les pays industrialisés. Les infections extradigestives dues aux Salmonelles mineures sont rares. Ces formes surviennent chez des malades immunodéprimés. La localisation pulmonaire des abcès à Salmonella enteritidis est rare ainsi que sa survenue au cours de l’infection à VIH. Cette observation rapporte un cas d’abcès pulmonaires à Salmonella avec bactériémie chez un homme ayant une infection à VIH1 en arrêt du traitement antirétroviral (ARV). Le patient a été traité par les bêtalactamines pendant trois semaines. L’évolution a été marquée par une amélioration clinique et radiologique

Blood culture: Profi le of bacterial infections of newborns admitted from maternity

Blood culture provides an undeniable ideal aid in the diagnosis of neonatal infection, its result is reliable. The aim of our work was to evaluate the bacteriological profi le of bacteraemias, newborns admitted from the hospital maternity IBN TOFAIL.A retrospective study on the cases of newborns hospitalized in the neonatal care unit, Mohamed VI University Hospital, Marrakech, originating from the delivery room of the IBN TOFAIL Gynecology and Obstetrics Department, during a period of 6 months From June to November 2016.125 blood cultures were collected, 43 were positive, representing an overall positivity rate of 34.4%. Positive blood cultures by coagulase-negative staphylococcal were 27. The other bacteremias were 16, represented by multiresistant germs, with the predominance of Klebsiella pneumoniae (5 cases), Acenitobacter Baumanii (4 cases) and Serratia marcescens in 3 cases.Bacteremia on admission; especially to multidrug-resistant germs, presents a major problem of therapeutic management. We insist on the need to improve the conditions of delivery in our context and to develop new diagnostic and therapeutic strategies.</p

Comparative study of the variability of chemical composition and antibacterial activity between two Moroccan endemic species essential oils: Origanum grosii Pau & Font Quer and Origanum elongatum (Bonnet) Emberger & Maire

Nowadays, plants have become one of the promising sources of chemical compounds that are used in several applications especially in the medicinal. This study aims to illustrate the variability of the chemical composition and the antibacterial activity essential oils of two endemic species in Morocco: Origanum grosii Pau &amp; Font Quer and Origanum elongatum (Bonnet) Emberger &amp; Maire. Each species was collected from two different altitudes in the same region “Taounate” (Morocco). The chemical composition as well as the antibacterial activity of essential oils extracted from dried plants via hydrodistillation was evaluated. Gas chromatography-Mass spectrometry (GC-MS) results showed that the essential oils contain forty-three components, representing around 99% of the total oil for all the tested samples. Carvacrol and Thymol are major compounds for both species. Staphylococcus aureus had a higher sensitivity for the first altitude in both species (MIC=MBC=1.3mg/mL), while Pseudomonas aeruginosa and Acinetobacter baumannii were the higher sensitive for the second altitude with (MIC=MBC=2.5mg/mL). In the light of these findings, Knowledge of the chemical composition and antibacterial activity of essential oils with environmental factors (altitude, edaphic, climatic and genetic factors…) is a very important quality criterion for their marketing and contributes to their valorization as a source of antibiotics after testing its toxicity on human

Clinical and immunological status of a newly diagnosed HIV positive population, in Marrakech, Morocco

Objective: To evaluate the clinical and the immune status of newly HIV diagnosed patients, in Marrakech city and its neighboring area, in Morocco. Methods: We performed a retrospective study on 235 patients who have been previously confirmed for HIV infection, and underwent a CD4 T cells using flow cytometry (FacsCount, Becton Dickinson®). Results: The mean age of patients was 34,3 ± 8,4 years (range: 14-55), with a male predominance (sex-ratio M/F=1.4). On basis of clinical data of the patients, 62% (n=146) of them were categorized as "category C", 18.4% (n=43) as "category B", and 19.6% (n=46) as "category A" according to CDC (Center for Disease Control) HIV classification. Among all of them, 60.4% (n=142) had less than 200 CD4T cells, 26% (n=61) had between 200 and 499 CD4T cells, and only 13.6% (n=32) showed a number of CD4T cells less or equal to 500/mm3. Conclusion: The results of this study reflect a significant delay in the diagnosis of HIV infected patients. Therefore, this delay may compromise timely management of HIV infected individuals and enhances propagation of the epidemic in our country. These data confirm the need for intensifying prevention efforts among high-risk population. Moreover, continuing education in HIV/AIDS among healthcare providers should be reinforced