305 research outputs found

    Drop Test Release Mechanism

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    Many boxes for shipping undergo drop tests by the manufacturer to ensure their durability. Certain constraints are necessary to successfully carry out these tests such as not damaging the box prior to the drop and maintaining consistency throughout every drop. Our team has designed a Drop Test Release Mechanism that addresses these constraints. It provides repetitive drops for different objects that vary in shape and size such as small electronics or parts. This device utilizes a soft-clamping mechanism that can release an object with minimal force applied onto it prior to drop. A frame made of 80/20 was designed to provide rigidity to the soft-clamping mechanism. The soft clamping mechanism supports the object between it by utilizing foam and a friction pad to induce a high friction force. The clamp can be adjusted for multiple sized objects by use of sliding rails that allow it to widen or tighten. Our design focuses on just the release of the test object. A test stand to introduce varying heights must be designed for a fully functional drop test measurement process. The final prototype was tested to analyze the effectiveness of our design. The tests involved verifying the repeatability of the drop mechanism by testing the object to see if it fell in the same orientation and with the same impact each time. The drop mechanism passed these tests but failed at a usability test and an electronic test. The report goes into detail about the design and testing of the prototype

    Relation between falciparum malaria and bacteraemia in Kenyan children: a population-based, case-control study and a longitudinal study.

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    BACKGROUND: Many investigators have suggested that malaria infection predisposes individuals to bacteraemia. We tested this hypothesis with mendelian randomisation studies of children with the malaria-protective phenotype of sickle-cell trait (HbAS). METHODS: This study was done in a defined area around Kilifi District Hospital, Kilifi, Kenya. We did a matched case-control study to identify risk factors for invasive bacterial disease, in which cases were children aged 3 months to 13 years who were admitted to hospital with bacteraemia between Sept 16, 1999, and July 31, 2002. We aimed to match two controls, by age, sex, location, and time of recruitment, for every case. We then did a longitudinal case-control study to assess the relation between HbAS and invasive bacterial disease as malaria incidence decreased. Cases were children aged 0-13 years who were admitted to hospital with bacteraemia between Jan 1, 1999, and Dec 31, 2007. Controls were born in the study area between Jan 1, 2006, and June 23, 2009. Finally, we modelled the annual incidence of bacteraemia against the community prevalence of malaria during 9 years with Poisson regression. RESULTS: In the matched case-control study, we recruited 292 cases-we recruited two controls for 236, and one for the remaining 56. Sickle-cell disease, HIV, leucocyte haemozoin pigment, and undernutrition were positively associated with bacteraemia and HbAS was strongly negatively associated with bacteraemia (odds ratio 0·36; 95% CI 0·20-0·65). In the longitudinal case-control study, we assessed data from 1454 cases and 10,749 controls. During the study period, the incidence of admission to hospital with malaria per 1000 child-years decreased from 28·5 to 3·45, with a reduction in protection afforded by HbAS against bacteraemia occurring in parallel (p=0·0008). The incidence of hospital admissions for bacteraemia per 1000 child-years also decreased from 2·59 to 1·45. The bacteraemia incidence rate ratio associated with malaria parasitaemia was 6·69 (95% CI 1·31-34·3) and, at a community parasite prevalence of 29% in 1999, 62% (8·2-91) of bacteraemia cases were attributable to malaria. INTERPRETATION: Malaria infection strongly predisposes individuals to bacteraemia and can account for more than half of all cases of bacteraemia in malaria-endemic areas. Interventions to control malaria will have a major additional benefit by reducing the burden of invasive bacterial disease. FUNDING: Wellcome Trust

    The Grizzly, October 13, 2011

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    UCARE Draws More Blood, Donors • Ursinus is Talking About Author Speaks on Novel • Annual Security and Fire Safety Report Released • Alcohol-Related Hospitalizations Rise, Confuse Administration • Berman Exhibit Honors Muhlenberg Family • Ursinus GSA Provides Genuine Acceptance for All • UC\u27s Dr. Clouser Lectures on Birds\u27 Habitats • Renaissance Band Takes Students Back in Time • Opinion: New Law in Alabama Intrudes on Citizens; Tips to Avoiding the Feared Freshman 15 • UC Water Polo Stresses Fun Over Seriousness • Men\u27s Soccer Gears Up for the Stretch Run • UC Rugby Making Bigger Commitmenthttps://digitalcommons.ursinus.edu/grizzlynews/1843/thumbnail.jp

    The role of religion in the longer-range future, April 6, 7, and 8, 2006

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    This repository item contains a single issue of the Pardee Conference Series, a publication series that began publishing in 2006 by the Boston University Frederick S. Pardee Center for the Study of the Longer-Range Future. This conference that took place during April 6, 7, and 8, 2006. Co-organized by David Fromkin, Director, Frederick S. Pardee Center for the Study of the Longer-Range Future, and Ray L. Hart, Dean ad interim Boston University School of TheologyThe conference brought together some 40 experts from various disciplines to ponder upon the “great dilemma” of how science, religion, and the human future interact. In particular, different panels looked at trends in what is happening to religion around the world, questions about how religion is impacting the current political and economic order, and how the social dynamics unleashed by science and by religion can be reconciled.Carnegie Council on Ethics and International Affair

    Travel- and Community-Based Transmission of Multidrug-Resistant Shigella sonnei Lineage among International Orthodox Jewish Communities

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    Shigellae are sensitive indicator species for studying trends in the international transmission of antimicrobial-resistant Enterobacteriaceae. Orthodox Jewish communities (OJCs) are a known risk group for shigellosis; Shigella sonnei is cyclically epidemic in OJCs in Israel, and sporadic outbreaks occur in OJCs elsewhere. We generated whole-genome sequences for 437 isolates of S. sonnei from OJCs and non-OJCs collected over 22 years in Europe (the United Kingdom, France, and Belgium), the United States, Canada, and Israel and analyzed these within a known global genomic context. Through phylogenetic and genomic analysis, we showed that strains from outbreaks in OJCs outside of Israel are distinct from strains in the general population and relate to a single multidrug-resistant sublineage of S. sonnei that prevails in Israel. Further Bayesian phylogenetic analysis showed that this strain emerged approximately 30 years ago, demonstrating the speed at which antimicrobial drug–resistant pathogens can spread widely through geographically dispersed, but internationally connected, communities

    Interpersonal communication about climate change:how messages change when communicated through simulated online social networks

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    Climate change communication research has mainly focused on how to communicate climate change effectively to the public. By contrast, how such information is then spread through interpersonal social networks has been neglected, despite being an essential component of cultural change. Using a Facebook-like format, we examined what types of climate change messages ‘survive’ when passed between individuals via communication network chains. We found that statements centred on conventional climate change topics (e.g., its impact on the natural world and human health) survived longer in communication chains than those with less conventional topics (e.g., its impact on societal competence, development, or communality). Moreover, statements about gains from mitigation (gain-frames) survived more than those about costs of non-mitigation (loss-frames) in initial communications, but loss-framed information survived more later in communication chains. In light of research showing that climate change messages focused on society and/or gain frames can motivate action, this research highlights a challenge by showing that these messages are less likely to be spread throughout society

    Cross-cultural variation in experiences of acceptance, camouflaging and mental health difficulties in autism:A registered report

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    Recent findings suggest that stigma and camouflaging contribute to mental health difficulties for autistic individuals, however, this evidence is largely based on UK samples. While studies have shown cross-cultural differences in levels of autism-related stigma, it is unclear whether camouflaging and mental health difficulties vary across cultures. Hence, the current study had two aims: (1) to determine whether significant relationships between autism acceptance, camouflaging, and mental health difficulties replicate in a cross-cultural sample of autistic adults, and (2) to compare these variables across cultures. To fulfil these aims, 306 autistic adults from eight countries (Australia, Belgium, Canada, Japan, New Zealand, South Africa, the United Kingdom, and the United States) completed a series of online questionnaires. We found that external acceptance and personal acceptance were associated with lower levels of depression but not camouflaging or stress. Higher camouflaging was associated with elevated levels of depression, anxiety, and stress. Significant differences were found across countries in external acceptance, personal acceptance, depression, anxiety, and stress, even after controlling for relevant covariates. Levels of camouflaging also differed across countries however this effect became non-significant after controlling for the covariates. These findings have significant implications, identifying priority regions for anti-stigma interventions, and highlighting countries where greater support for mental health difficulties is needed
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