139 research outputs found

    Des bibliothèques Gay Friendly ? Conférences sur les questions de genre en bibliothèque

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    Comprend des références bibliographique

    Bibliothèques Gay Friendly ? (Des)

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    Construit sur la base de conférences présentées à l’Ifla dans le cadre du groupe d’intérêt spécial « Publics LGBT », cet ouvrage a été conçu par la commission Légothèque qui a traduit les productions de nos collègues étrangers, convaincus que la bibliothèque peut être cet « endroit sûr au sein de la culture dominante ». Ces conférences sont présentées sous une forme éditorialisée, soulignant les problématiques professionnelles, présentant des outils pratiques et contextualisant, selon la zone géographique, le métier du bibliothécaire au service de toutes les communautés. Un éclairage inédit en France sur les pratiques des bibliothèques à destination et en faveur des minorités sexuelles et de genre

    Intense exercise training induces adaptation in expression and responsiveness of cardiac β-adrenoceptors in diabetic rats

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    <p>Abstract</p> <p>Background</p> <p>Informations about the effects of intense exercise training on diabetes-induced myocardial dysfunctions are lacking. We have examined the effects of intense exercise training on the cardiac function of diabetic rats, especially focusing on the Langendorff β-adrenergic responsiveness and on the β-adrenoceptors protein expression.</p> <p>Methods</p> <p>Control or Streptozotocin induced-diabetic male Wistar rats were randomly assigned to sedentary or trained groups. The training program consisted of 8 weeks running on a treadmill (10° incline, up to 25 m/min, 60 min/day) and was considered to be intense for diabetic rats.</p> <p>Results</p> <p>This intense exercise training amplified the <it>in vivo </it>diabetes-induced bradycardia. It had no effect on Langendorff basal cardiac contraction and relaxation performances in control and diabetic rats. In diabetic rats, it accentuated the Langendorff reduced responsiveness to β-adrenergic stimulation. It did not blunt the diabetes-induced decrease of β1-adrenoceptors protein expression, displayed a significant decrease in the β2-adrenoceptors protein expression and normalized the β3-adrenoceptors protein expression.</p> <p>Conclusions</p> <p>Intense exercise training accentuated the decrease in the myocardial responsiveness to β-adrenergic stimulation induced by diabetes. This defect stems principally from the β2-adrenoceptors protein expression reduction. Thus, these results demonstrate that intense exercise training induces specific effects on the β-adrenergic system in diabetes.</p

    Contribution of Fluorescence Techniques in Determining the Efficiency of the Non-thermal Plasma Treatment

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    We have recently developed a non-thermal plasma (NTP) equipment intended to sterilize fragile medical devices and maintain the sterile state of items downstream the treatment. With traditional counts on agar plate a six log reduction of Staphylococcus aureus viability was obtained within 120 min of O2, Ar, or N2 NTP treatments. However to determine the best NTP process, we studied the different physiological states of S. aureus by flow cytometry (FC) and confocal laser scanning microscopy (CLSM) focusing on the esterasic activity and membrane integrity of the bacteria. Two fluorochromes, 5-(and-6)-carboxy-2′,7′-dichlorofluorescein diacetate and propidium iodide were used in order to distinguish three sub-populations: metabolically active, permeabilized, and damaged bacteria that can be in the viable but nonculturable state. FC and CLSM highlight that O2 and Ar NTP treatments were the most attractive processes. Indeed, a 5 min of Ar NTP generated a high destruction of the structure of bacteria and a 120 min of O2 NTP treatment led to the higher decrease of the total damaged bacteria population. SEM observations showed that in presence of clusters, bacteria of upper layers are easily altered compared to bacteria in the deeper layers. In conclusion, the plate counting method is not sufficient by itself to determine the best NTP treatment. FC and CLSM represent attractive indicator techniques to select the most efficient gas NTP treatment generating the lowest proportion of viable bacteria and the most debris

    Positive and Negative Urgency as a single coherent construct: Evidence from a large‐scale network analysis in clinical and non‐clinical samples

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    Aims: Negative and positive urgency are emotion-related impulsivity traits that are thought to be transdiagnostic factors in psychopathology. However, it has recently been claimed that these two traits are closely related to each other and that considering them separately might have limited conceptual and methodological value. The present study aimed to examine whether positive and negative urgency constructs constitute separate impulsivity traits. Methods: In contrast to previous studies that have used latent variable approaches, this study employed an item-based network analysis conducted in two different samples: a large sample of non-clinical participants (N = 18,568) and a sample of clinical participants with psychiatric disorders (N = 385). Results: The network analysis demonstrated that items denoting both positive and negative urgency cohere as a single cluster of items termed “general urgency” in both clinical and non-clinical samples, thereby suggesting that differentiating positive and negative urgency as separate constructs is not necessary. Conclusion: These findings have important implications for the conceptualization and assessment of urgency and, more broadly, for future research on impulsivity, personality, and psychopathology

    Des bibliothèques Gay Friendly

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    Construit sur la base de conférences présentées à l’Ifla dans le cadre du groupe d’intérêt spécial « Publics LGBT », cet ouvrage a été conçu par la commission Légothèque qui a traduit les productions de nos collègues étrangers, convaincus que la bibliothèque peut être cet « endroit sûr au sein de la culture dominante ». Ces conférences sont présentées sous une forme éditorialisée, soulignant les problématiques professionnelles, présentant des outils pratiques et contextualisant, selon la zone géographique, le métier du bibliothécaire au service de toutes les communautés. Un éclairage inédit en France sur les pratiques des bibliothèques à destination et en faveur des minorités sexuelles et de genre

    Des bibliothèques gay friendly ?

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    Retour sur la publication d\u27un livre numérique autour de l\u27inclusion des publics LGBT dans les bibliothèques. Un travail collectif entre la commission Légothèque et les Presses de l\u27Enssib

    Une bibliothèque au Point éphémère !

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    Cet été, le Point Éphémère, un lieu emblématique de Paris, a accueilli une bibliothèque LGBT+, retour sur le projet avec sa créatrice, Albane Linyer
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