Factors Affecting Environmental Concern in Bloomington-Normal Residents

This study focuses on what actions residents of Bloomington and Normal Illinois are taking to lessen their impact on the environment. These actions demonstrate their concern for the environment. Finding out what influences environmentally friendly actions is a difficult process because of the complexity and the number of factors that contribute to these decisions. Not only are the factors numerous, but they also vary in intensity. This study uncovers a few of the contributing factors to environmental concern of Bloomington-Normal residents

Ethnobotanical molluscicides

Molluscan are always responsible for human threat direct or indirect ways. A large number of molluscan serve as intermediate host for fasciolosis and schistosomiasis. These both diseases has great outbreak over exploiting the human health and economy. Their prevalence has been increasing worldwide due in large part to programme of water resource development, and poor hygienic conditions. The freshwater gastropods (snails) are the intermediate host for the larval stages of these two trematodes worms where they completed asexual phases of different development stages. Large numbers of treatment are available to tackle the problem of these two neglected tropical disease (NTDs). One of the easiest methods to break the transmission of these diseases is to de-link the intermediate host from helminths life cycle by the use of molluscicides. Currently there is an increased interest to identified the plant and explore their therapeutic potential as a molluscicides. Since the biomolluscicide are the safest, eco-friendly, fast biodegradability and cost effective method for molluscan control as compared to other synthetic counterparts, that are high imported cost, toxicity in non-target biota’s, and developing resistance in molluscan. This review is generally concerned with the efforts being made to concise the resources based on the ethnobotanical molluscicides to control the pest population and provide the data source of new researcher to explore the most promising candidates of nature i.e. plant molluscicides, as they are very effective tool for integrated vector management programme yet harmless to other non-target aquatic biota’s. DOI: http://dx.doi.org/10.5281/zenodo.551562

Large vaginal varicosities in the pregnancy without any known systemic disease: a rare case report

Vaginal varices during pregnancy is a rare condition. Only a few cases have been reported in the literature. Most vaginal varices are asymptomatic, but some are associated with a sense of local mass, or severe discomfort and spontaneous vaginal bleeding. A 26-year-old woman was admitted for spontaneous vaginal bleeding at 38 weeks’ gestation. Upon pelvic inspection, we observed dilated vascular structure on the sub-urethral vaginal wall, and the trans-labial ultrasound imaging revealed a blood flow along the vaginal area, confirming the presence of a vaginal varicosity (Figure 3). We concluded that the mass was large vaginal varicosities as there was no discernible etiolgy. Instead of a normal delivery, we performed a cesarean section to prevent the potential risk of the profuse vaginal bleeding. For long-term management, close observation in postpartum period was recommended. Spontaneous resolution is a potential outcome and this is what our patient experienced

Atmospheric Aerosols Monitoring: Ground and Satellite-Based Instruments

Aerosols are submicron particles suspended in the atmosphere which affect Earth’s energy balance directly by scattering and absorbing the of solar radiation. In addition, they can indirectly affect radiation balance by changing the micro-physical and optical properties of the cloud. The difficulties in accessing the contribution of aerosols to radiative balance are caused partly due to incomplete knowledge of spatiotemporal variabilities in physicochemical and optical properties of aerosols on regional to global scale. Several state-of-the-art instrumentation techniques for ground-based measurements and satellite remote sensing technologies have been developed in past three decades to monitor physicochemical and optical properties of aerosols for a better understanding of radiative balance and feedback mechanisms. Satellite retrievals of moderate resolution imaging spectroradiometer (MODIS), ozone monitoring instrument (OMI), multi-angle imaging spectroradiometer (MISR) are used for this purpose. Ground-based measurements of aerosol properties provide a basis for validation of atmospheric correction procedures and can be used for validation of aerosol models used in atmospheric correction algorithms. This chapter describes in details about the widely used ground- and satellite-based remote sensing instruments for aerosol monitoring

NOVEL TOPICAL ANTI-AGING HERBAL COMPOSITION

Objective: Anti-aging formulations are among the premier skin care products in the global market that are in huge demand. Different treatments are available to slow down skin aging, but are very expensive and are often found to produce adverse reactions to the skin in prolong use. Hence, present study has been designed to formulate poly herbal anti-aging skin care products and their evaluation thereon. Methods: Anti-aging herbal skin care cream, gel and serum were prepared using two medicinal plants Hippophae salicifolia and Celosia argentea along with three bioactives caffeine, rutin and bakuchiol. The formulations were evaluated for physicochemical parameters like pH, texture analysis, acid value, short-term stability study, etc. Phenolics and flavanoid content were determined. Anti-aging potential was gauged by in silico studies using the glide tool of ‘Schrodinger’. Results: Cream, gel and serum showed good physical appearance and were free from gritty particles and with smooth texture. Accelerated stability studies indicated insignificant changes in physicochemical parameters of the formulations. Based on the docking score and interaction with amino acid, compounds present in the plant extracts and bioactive showed good anti-aging activity. Conclusion: The prepared herbal anti-aging formulations were found to be stable and exhibited good potential as an anti-aging combination. So, they can be used as an effective combination to protect skin from aging

Optimizing Antibiotic Prescriptions and Infectious Disease Management in Hospitals using Neural Networks

This study introduces an innovative approach to antibiotic optimization and improved infectious disease management in healthcare facilities. Antibiotic stewardship and patient-specific outcomes are prioritized in the suggested strategy that uses neural networks to increase the precision and utility of antibiotic prescriptions. There are three primary algorithms at the heart of the technique. When it comes to identifying infectious illnesses from a picture, Algorithm 1 uses a Convolutional Neural Network (CNN). In order to provide educated antibiotic recommendations, Algorithm 2 uses a Recurrent Neural Network (RNN) containing Long Short-Term Memory (LSTM) cells. The third algorithm integrates reinforcement learning to automatically modify therapies based on patient results and antibiotic use. The outcomes prove that the suggested strategy is better than the status quo. The F1 score, recall, and precision all increase dramatically, and the overall diagnostic accuracy is much higher. Antibiotic stewardship also improves noticeably, leading to fewer antibiotic prescriptions, more effective measures against antibiotic resistance, better health outcomes for patients, and lower overall healthcare expenditures. Addressing the difficulties of fluctuating patient states and changing disease patterns, the suggested methodology provides a comprehensive strategy for managing infectious diseases. Using this method, antibiotic prescriptions may be optimized while still meeting all legal and ethical requirements. The ethical use of AI in healthcare is further ensured by constant monitoring and flexibility

Local Anesthetic Systemic Toxicity

Local anesthetics are used very often in medicine and dentistry. They have few adverse effects, but the increased use of these drugs has resulted in a higher incidence of local and systemic anesthetic toxicity (LAST). From the initial symptoms to the deleterious effects on cardiac and the central nervous system, LAST is an important consequence of which we should be aware. LAST is known since the introduction and use of local anesthetics; it was originally associated with seizures and respiratory failure. However, in the 1970s, side effects on the heart were also identified, as the fatal cardiac toxicity associated with bupivacaine was discovered in healthy patients. Prevention and safe administration of regional anesthesia remains primary factors in the avoidance of the toxicity of these drugs. When a patient has LAST, treatment should be started immediately to reduce seizures. If there is cardiac arrest, follow ACLS guidelines. Intravenous lipids improve cardiac conduction, contractility and coronary perfusion by removing liposoluble local anesthetic from cardiac tissue

Strengthening fruit and vegetable supply-chain policies and programmes in India

India currently has one of the highest numbers of malnourished children in the world – 8% stunted, 43% underweight, and 20% overweight and obese. This distressing public health scenario is further exacerbated by a high prevalence of multiple micronutrient deficiencies among these children – such as iron deficiency anaemia and Vitamin A deficiency. Evidence shows linkages between early life malnourishment (either underweight or overweight-obesity) and predisposition to developing chronic diseases in adult life. Consuming 400g/day of fresh fruits and vegetables can help prevent micronutrient deficiencies while promoting overall growth and development. However, national averages indicate that children do not consume even 40% of the daily recommended amounts. Public Health Foundation of India (PHFI) undertook a study titled ‘Leveraging fruit and vegetable supply policies to tackle the dual burden of malnutrition in India’ supported by the Leveraging Agriculture for Nutrition in South Asia (LANSA) consortium at the M S Swaminathan Research Foundation (MSSRF). The study, discussed in this Brief aimed to analyse the policy environment related with fruit and vegetable (FV) supply in India to identify opportunities for policy to increase access to, and thus intakes of FV, especially among children.Department for International Development (DFID)UKAI

Pharmacological Activities of Aminophenoxazinones

Aminophenoxazinones are degradation products resulting from the metabolism of different plant species, which comprise a family of natural products well known for their pharmacological activities. This review provides an overview of the pharmacological properties and applications proved by these compounds and their structural derivatives during 2000-2021. The bibliography was selected according to our purpose from the references obtained in a SciFinder database search for the Phx-3 structure (the base molecule of the aminophenoxazinones). Compounds Phx-1 and Phx-3 are among the most studied, especially as anticancer drugs for the treatment of gastric and colon cancer, glioblastoma and melanoma, among others types of relevant cancers. The main information available in the literature about their mechanisms is also described. Similarly, antibacterial, antifungal, antiviral and antiparasitic activities are presented, including species related directly or indirectly to significant diseases. Therefore, we present diverse compounds based on aminophenoxazinones with high potential as drugs, considering their levels of activity and few adverse effects