366 research outputs found
Effect of broodstock holding environment on egg quality in farmed brown trout (Salmo trutta)
Brown trout (Salmo trutta) broodstock from a
single population were separated prior to spawning and
exposed to two different holding environments: a
‘raceway system’ and a ‘tank system’. Eggs were
stripped from females and 13 measures of egg quality
were collected, analysed individually, combined by
principle components analysis into an integrated egg
quality score which was validated against egg survival.
The multivariate egg quality score (PC1) differed for
fish held in the tank and raceway systems. Egg survival,
chorion breaking strength and chorion Se concentrations
were higher in eggs produced by broodstock held in the
tank system compared to those in the raceway system.
In contrast, chorion concentrations of P and K were
higher in eggs from fish held in the raceway system.
The results suggest that brown trout broodstock reared
in tank systems produced higher quality eggs compared
to trout reared in raceways. Finally, this study also
indicates that multivariate statistical analysis can be
used to determine egg quality from multiple egg
parameters
Finite-size scaling properties of random transverse-field Ising chains : Comparison between canonical and microcanonical ensembles for the disorder
The Random Transverse Field Ising Chain is the simplest disordered model
presenting a quantum phase transition at T=0. We compare analytically its
finite-size scaling properties in two different ensembles for the disorder (i)
the canonical ensemble, where the disorder variables are independent (ii) the
microcanonical ensemble, where there exists a global constraint on the disorder
variables. The observables under study are the surface magnetization, the
correlation of the two surface magnetizations, the gap and the end-to-end
spin-spin correlation for a chain of length . At criticality, each
observable decays typically as in both ensembles, but the
probability distributions of the rescaled variable are different in the two
ensembles, in particular in their asymptotic behaviors. As a consequence, the
dependence in of averaged observables differ in the two ensembles. For
instance, the correlation decays algebraically as 1/L in the canonical
ensemble, but sub-exponentially as in the microcanonical
ensemble. Off criticality, probability distributions of rescaled variables are
governed by the critical exponent in both ensembles, but the following
observables are governed by the exponent in the microcanonical
ensemble, instead of the exponent in the canonical ensemble (a) in the
disordered phase : the averaged surface magnetization, the averaged correlation
of the two surface magnetizations and the averaged end-to-end spin-spin
correlation (b) in the ordered phase : the averaged gap. In conclusion, the
measure of the rare events that dominate various averaged observables can be
very sensitive to the microcanonical constraint.Comment: 24 page
Improving tree mortality models by accounting for environmental influences
Tree-ring chronologies have been widely used in studies of tree mortality where variables of recent growth act as an indicator of tree physiological vigour. Comparing recent radial growth of live and dead trees thus allows estimating probabilities of tree mortality. Sampling of mature dead trees usually provides death-year distributions that may span over years or decades. Recent growth of dead trees (prior to death) is then computed during a number of periods, whereas recent growth (prior to sampling) for live trees is computed for identical periods. Because recent growth of live and dead trees is then computed for different periods, external factors such as disturbance or climate may influence growth rates and, thus, mortality probability estimations. To counteract this problem, we propose the truncating of live-growth series to obtain similar frequency distributions of the "last year of growth" for the populations of live and dead trees. In this paper, we use different growth scenarios from several tree species, from several geographic sources, and from trees with different growth patterns to evaluate the impact of truncating on predictor variables and their selection in logistic regression analysis. Also, we assess the ability of the resulting models to accurately predict the status of trees through internal and external validation. Our results suggest that the truncating of live-growth series helps decrease the influence of external factors on growth comparisons. By doing so, it reinforces the growth-vigour link of the mortality model and enhances the model's accuracy as well as its general applicability. Hence, if model parameters are to be integrated in simulation models of greater geographical extent, truncating may be used to increase model robustness
Demonstration of radon removal from SF6 using molecular sieves
The gas SF6 has become of interest as a negative ion drift gas for use in directional
dark matter searches. However, as for other targets in such searches, it is important that radon
contamination can be removed as this provides a source of unwanted background events. In this
work we demonstrate for the first time filtration of radon from SF6 gas by using a molecular
sieve. Four types of sieves from Sigma-Aldrich were investigated, namely 3Ã…, 4Ã…, 5Ã… and 13X.
A manufactured radon source was used for the tests. This was attached to a closed loop system in
which gas was flowed through the filters and a specially adapted Durridge RAD7 radon detector.
In these measurements, it was found that only the 5Ã… type was able to significantly reduce the
radon concentration without absorbing the SF6 gas. The sieve was able to reduce the initial radon
concentration of 3875 ± 13 Bqm−3
in SF6 gas by 87% when cooled with dry ice. The ability of
the cooled 5Ã… molecular sieve filter to significantly reduce radon concentration from SF6 provides
a promising foundation for the construction of a radon filtration setup for future ultra-sensitive SF6
gas rare-event physics experiments
Random walks and polymers in the presence of quenched disorder
After a general introduction to the field, we describe some recent results
concerning disorder effects on both `random walk models', where the random walk
is a dynamical process generated by local transition rules, and on `polymer
models', where each random walk trajectory representing the configuration of a
polymer chain is associated to a global Boltzmann weight. For random walk
models, we explain, on the specific examples of the Sinai model and of the trap
model, how disorder induces anomalous diffusion, aging behaviours and Golosov
localization, and how these properties can be understood via a strong disorder
renormalization approach. For polymer models, we discuss the critical
properties of various delocalization transitions involving random polymers. We
first summarize some recent progresses in the general theory of random critical
points : thermodynamic observables are not self-averaging at criticality
whenever disorder is relevant, and this lack of self-averaging is directly
related to the probability distribution of pseudo-critical temperatures
over the ensemble of samples of size . We describe the
results of this analysis for the bidimensional wetting and for the
Poland-Scheraga model of DNA denaturation.Comment: 17 pages, Conference Proceedings "Mathematics and Physics", I.H.E.S.,
France, November 200
Pinned Balseiro-Falicov Model of Tunneling and Photoemission in the Cuprates
The smooth evolution of the tunneling gap of Bi_2Sr_2CaCu_2O_8 with doping
from a pseudogap state in the underdoped cuprates to a superconducting state at
optimal and overdoping, has been interpreted as evidence that the pseudogap
must be due to precursor pairing. We suggest an alternative explanation, that
the smoothness reflects a hidden SO(N) symmetry near the (pi,0) points of the
Brillouin zone (with N = 3, 4, 5, or 6). Because of this symmetry, the
pseudogap could actually be due to any of a number of nesting instabilities,
including charge or spin density waves or more exotic phases. We present a
detailed analysis of this competition for one particular model: the pinned
Balseiro-Falicov model of competing charge density wave and (s-wave)
superconductivity. We show that most of the anomalous features of both
tunneling and photoemission follow naturally from the model, including the
smooth crossover, the general shape of the pseudogap phase diagram, the
shrinking Fermi surface of the pseudogap phase, and the asymmetry of the
tunneling gap away from optimal doping. Below T_c, the sharp peak at Delta_1
and the dip seen in the tunneling and photoemission near 2Delta_1 cannot be
described in detail by this model, but we suggest a simple generalization to
account for inhomogeneity, which does provide an adequate description. We show
that it should be possible, with a combination of photoemission and tunneling,
to demonstrate the extent of pinning of the Fermi level to the Van Hove
singularity. A preliminary analysis of the data suggests pinning in the
underdoped, but not in the overdoped regime.Comment: 18 pages LaTeX, 26 ps. figure
Drug-gene interactions of antihypertensive medications and risk of incident cardiovascular disease: A pharmacogenomics study from the CHARGE consortium
Background Hypertension is a major risk factor for a spectrum of cardiovascular diseases (CVD), including myocardial infarction, sudden death, and stroke. In the US, over 65 million people have high blood pressure and a large proportion of these individuals are prescribed antihypertensive medications. Although large long-term clinical trials conducted in the last several decades have identified a number of effective antihypertensive treatments that reduce the risk of future clinical complications, responses to therapy and protection from cardiovascular events vary among individuals. Methods Using a genome-wide association study among 21,267 participants with pharmaceutically treated hypertension, we explored the hypothesis that genetic variants might influence or modify the effectiveness of common antihypertensive therapies on the risk ofmajor cardiovascular outcomes. The classes of drug treatments included angiotensin-converting enzyme inhibitors, beta-blockers, calcium channel blockers, and diuretics. In the setting of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium, each study performed array-based genome-wide genotyping, imputed to HapMap Phase II reference panels, and used additive genetic models in proportional hazards or logistic regressionmodels to evaluate drug-gene interactions for each of four therapeutic drug classes. We used meta-analysis to combine study-specific interaction estimates for approximately 2 million single nucleotide polymorphisms (SNPs) in a discovery analysis among 15,375 European Ancestry participants (3,527 CVD cases) with targeted follow-up in a case-only study of 1,751 European Ancestry GenHAT participants as well as among 4,141 African-Americans (1,267 CVD cases). Results Although drug-SNP interactions were biologically plausible, exposures and outcomes were well measured, and power was sufficient to detect modest interactions, we did not identify any statistically significant interactions from the four antihypertensive therapy meta-analyses (Pinteraction > 5.0×10-8). Similarly, findings were null for meta-analyses restricted to 66 SNPs with significant main effects on coronary artery disease or blood pressure from large published genom
Size Doesn't Matter: Towards a More Inclusive Philosophy of Biology
notes: As the primary author, O’Malley drafted the paper, and gathered and analysed data (scientific papers and talks). Conceptual analysis was conducted by both authors.publication-status: Publishedtypes: ArticlePhilosophers of biology, along with everyone else, generally perceive life to fall into two broad categories, the microbes and macrobes, and then pay most of their attention to the latter. ‘Macrobe’ is the word we propose for larger life forms, and we use it as part of an argument for microbial equality. We suggest that taking more notice of microbes – the dominant life form on the planet, both now and throughout evolutionary history – will transform some of the philosophy of biology’s standard ideas on ontology, evolution, taxonomy and biodiversity. We set out a number of recent developments in microbiology – including biofilm formation, chemotaxis, quorum sensing and gene transfer – that highlight microbial capacities for cooperation and communication and break down conventional thinking that microbes are solely or primarily single-celled organisms. These insights also bring new perspectives to the levels of selection debate, as well as to discussions of the evolution and nature of multicellularity, and to neo-Darwinian understandings of evolutionary mechanisms. We show how these revisions lead to further complications for microbial classification and the philosophies of systematics and biodiversity. Incorporating microbial insights into the philosophy of biology will challenge many of its assumptions, but also give greater scope and depth to its investigations
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