420 research outputs found

    Perspectives of Suburban Public School Teachers on the Characteristics of Students At-Risk for Dropping out of School

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    This study focuses on a major problem facing today’s educators: high school dropouts. Numerous studies have been conducted to identify the reasons that students drop out of school and programs that may address the needs of students at-risk for dropping out of school. Literature in this area was reviewed to identify what can be learned from these studies. Research questions addressed differences in teacher perspectives of the characteristics of elementary, middle, and high school struggling students. Differences in teachers’ perspectives based on tenure and type of teaching assignment were examined. A sequential, mixed methods approach was taken. The researchers began with a quantitative survey of 108 teachers, followed by focus groups with 12 elementary and secondary teachers. The research was conducted in two suburban school districts. The analysis indicated that characteristics of at-risk students fall into four dimensions: Family Involvement, Behavior, Achievement, and Family Background. Significant differences were found for Achievement with secondary teachers reporting higher mean scores than elementary teachers. Additionally, significant differences were identified for elementary classroom teachers in regards to Achievement. Elementary classroom teachers reported higher mean scores than elementary non-classroom teachers for this dimension. The data gained from the study can be used to inform decisions regarding the identification of at-risk students. It also provides information related to support services aimed at assisting struggling students. Determining if differences in perspectives exist among the levels of teachers can be beneficial in identifying students before they become at-risk for dropping out of school. This study benefits students, parents, teachers, school administrators, central office administrators, and school committee members as these stakeholders look to address the dropout problem that plagues high schools across the nation

    Characteristics of At-Risk Students

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    This study focused on a major problem facing today’s educators: high school dropouts. Research questions addressed differences in teacher perspectives of the characteristics of struggling students. Differences in teachers’ perspectives based on teaching level (elementary & secondary) were examined. The researcher conducted focus groups with a total of 12 teachers. The research was conducted in two suburban districts. Focus group questions were designed following a survey administered to 108 suburban public school teachers. The survey responses reported previously identified four dimensions of characteristics of at-risk students: behavior, achievement, family involvement, and family background. The data from the focus groups can be used to inform decisions regarding the identification and support of at-risk students

    Characteristics of At-Risk Students: Opinions of Elementary and Secondary School Teachers

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    This study focused on a major problem facing today’s educators: high school dropouts. Research questions addressed differences in teacher perspectives of the characteristics of struggling students. Differences in teachers’ perspectives based on teaching level (elementary & secondary) were examined. The researcher conducted focus groups with a total of 12 teachers. The research was conducted in two suburban districts. Focus group questions were designed following a survey administered to 108 suburban public school teachers. The survey responses reported previously identified four dimensions of characteristics of at-risk students: behavior, achievement, family involvement, and family background. The data from the focus groups can be used to inform decisions regarding the identification and support of at-risk students

    Flow-volume curve analysis for predicting recurrence after endoscopic dilation of airway stenosis

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    The flow-volume curve is a simple test for diagnosing upper airway obstruction. We evaluated its use to predict recurrence in patients undergoing endoscopic dilation for treatment of benign upper airway stenosis

    A Survey on the Distribution of Ovothiol and ovoA Gene Expression in Different Tissues and Cells: A Comparative Analysis in Sea Urchins and Mussels

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    Ovothiols are histidine-derived thiols produced by a variety of marine invertebrates, protists and bacteria. These compounds, which are among the strongest natural antioxidants, are involved in controlling the cellular redox balance due to their redox exchange with glutathione. Although ovothiols were initially reported as protective agents against environmental stressors, new evidence suggests that they can also act as pheromones and participate in fundamental biological processes such as embryogenesis. To get further insight into the biological roles of ovothiols, we compared ovothiol biosynthesis in the sea urchin Paracentrotus lividus and in the mussel Mytilus galloprovincialis, the two species that represent the richest sources of these compounds among marine invertebrates. Ovothiol content was measured in different tissues and in the immune cells from both species and the expression levels of ovoA, the gene responsible for ovothiol biosynthesis, was inferred from publicly available transcriptomes. A comparative analysis of ovothiol biosynthesis in the two species allowed the identification of the tissues and cells synthesizing the metabolite and highlighted analogies and differences between sea urchins and mussels. By improving our knowledge on the biological roles of ovothiols and pointing out the existence of sustainable natural sources for their isolation, this study provides the basis for future biotechnological investigations on these valuable compounds

    Setting up of an experimental site for the continuous monitoring of water discharge, suspended sediment transport and groundwater levels in a mediterranean basin. Results of one year of activity

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    The study of suspended sediment transport requires continuous measurement of water discharge to better understand the sediment dynamics. Furthermore, a groundwater monitoring network can support the stream discharge measures, as it reveals how the interactions between surface water and groundwater may affect runoff and consequently sediment transport during flood events. An experimental site for the continuous monitoring of water discharge, suspended sediment transport and groundwater levels was set up in the Carapellotto basin (27.17 km2), which is located in Apulia, Southern Italy. Seven flood events that occurred in the operation timespan were covered with a full record of both water discharge and sediment concentration. Some monitoring problems, largely due to the clogging of the float by mud, suggested to improve the experimental set up. The results show high values of suspended sediments concentration which indicate the sub-basin’s key role in the sediment delivery to the whole river system, while counter-clockwise hysteresis loops are the most frequent due to the basin characteristics. The effects of the interaction between surface water and groundwater are related not only to the flood magnitude but also to the hydrogeological features in the hyporheic zone

    Atualidades no Diabetes gestacional: Updates on gestational Diabetes

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    Introdução - diabetes mellitus gestacional refere-se Ă  hiperglicemia diagnosticada durante o segundo ou terceiro trimestre da gravidez. Sua prevalĂŞncia varia de <1% a 28% dependendo do paĂ­s e dos critĂ©rios de diagnĂłstico.  Objetivos - revisĂŁo na literatura atualizando conceitos, diagnĂłstico e novas possibilidades terapĂŞuticas no diabetes gestacional. Metodologia - revisĂŁo bibliográfica, com descritores: diabetes e gestação, gestação de risco, prĂ©-natal, hipoglicemiantes orais e cuidados no puerpĂ©rio. Resultados -   aumento no consumo de açúcar Ă© paralelo ao aumento do excesso de peso, diabetes gestacional e diabetes mellitus tipo 2 nas Ăşltimas quatro dĂ©cadas. A triagem universal associada a mudanças de estilo de vida (dieta e exercĂ­cio) Ă© a principal abordagem durante gestação.  A metformina ganhou espaço definitivo, precedendo Ă  introdução da insulina. O telemonitoramento deve ser incentivado. Fundamental o controle pĂłs-parto, muito negligenciado, na triagem do diabetes tipo 2. Conclusões – Alguns pontos muito bem definidos: O rastreamento universal Ă© obrigatĂłrio, existindo ainda algumas divergĂŞncias na metodologia empregada (jejum ou teste com carga), as mudanças nos hábitos de vida e o exercĂ­cio fĂ­sico sĂŁo fundamentais no controle. Entretanto sĂŁo de difĂ­cil aderĂŞncia. A metformina Ă© uma realidade que deve estar em todos os protocolos, fundamental o acompanhamento no pĂłs-parto, devendo ser considerado a longo prazo, devido Ă  relação com o diabetes tipo 2 no futuro das pacientes. Considerar adequado o monitoramento Ă  distância com resultados promissores

    Characterization of anti-proliferative and anti-oxidant effects of nano-sized vesicles from Brassica oleracea L. (Broccoli)

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    In this in vitro study, we test our hypothesis that Broccoli-derived vesicles (BDVs), combining the anti-oxidant properties of their components and the advantages of their structure, can influence the metabolic activity of different cancer cell lines. BDVs were isolated from homogenized fresh broccoli (Brassica oleracea L.) using a sucrose gradient ultracentrifugation method and were characterized in terms of physical properties, such as particle size, morphology, and surface charge by transmission electron microscopy (TEM) and laser doppler electrophoresis (LDE). Glucosinolates content was assessed by RPLC–ESI–MS analysis. Three different human cancer cell lines (colorectal adenocarcinoma Caco-2, lung adenocarcinoma NCI-H441 and neuroblastoma SHSY5Y) were evaluated for metabolic activity by the MTT assay, uptake by fluorescence and confocal microscopy, and anti-oxidant activity by a fluorimetric assay detecting intracellular reactive oxygen species (ROS). Three bands were obtained with average size measured by TEM based size distribution analysis of 52 nm (Band 1), 70 nm (Band 2), and 82 nm (Band 3). Glucobrassicin, glucoraphanin and neoglucobrassicin were found mostly concentrated in Band 1. BDVs affected the metabolic activity of different cancer cell lines in a dose dependent manner compared with untreated cells. Overall, Band 2 and 3 were more toxic than Band 1 irrespective of the cell lines. BDVs were taken up by cells in a dose- and time-dependent manner. Pre-incubation of cells with BDVs resulted in a significant decrease in ROS production in Caco-2 and NCI-H441 stimulated with hydrogen peroxide and SHSY5Y treated with 6-hydroxydopamine, with all three Bands. Our findings open to the possibility to find a novel “green” approach for cancer treatment, focused on using vesicles from broccoli, although a more in-depth characterization of bioactive molecules is warranted

    Does Myasthenia Gravis Affect Long-Term Survival in Thymic Carcinomas? An ESTS Database Analysis

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    Background: Thymic carcinoma is a rare and highly malignant tumor with a dismal prognosis, which occasionally coexists with myasthenia gravis (MG). This study aims to investigate the MG incidence on a surgical cohort of patients with thymic carcinoma and to explore its influence on long-term survival. Methods: the prospectively collected data from the ESTS database on thymic epithelial tumors were reviewed. Clinical, pathological, and survival information on thymic carcinoma were analyzed. Results: the analysis was conducted on 203 patients, with an equal gender distribution (96 males and 107 females). MG was detected in 22 (10.8%) patients, more frequently elderly (>60 years, p = 0.048) and male (p = 0.003). Induction therapy was performed in 22 (10.8%) cases. After surgery, 120 (59.1%) patients had a Masaoka stage II-III while complete resection (R0) was achieved in 158 (77.8%). Adjuvant therapy was performed in 68 cases. Mean follow-up was 60 (SD = 14) months. The 3-year, 5-year and 10-year survival rates were 79%, 75% and 63%, respectively. MG did not seem to influence long-term survival (5-year survival in non-MG-TCs 78% vs. 50% in MG-TCs, p = ns) as age < 60 years, female gender, early Masaoka stage, and postoperative radiotherapy did, conversely. Conclusions: myasthenia occurred in about 10% of thymic carcinomas and it did not seem to affect significantly the long-term prognosis in surgically treated thymic carcinoma-patients

    Spatial Variations of Heavy Metals in the Soils of Vegetable-Growing Land along Urban-Rural Gradient of Nanjing, China

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    China has experienced rapid urbanization in recent years. The acceleration of urbanization has created wealth and opportunity as well as intensified ecological and environmental problems, especially soil pollution. Our study concentrated on the variation of heavy metal content due to urbanization in the vegetable-growing soil. Laws and other causes of the spatial-temporal variation in heavy metal content of vegetable-growing soils were analyzed for the period of urbanization in Nanjing (the capital of Jiangsu province in China). The levels of Cu, Zn, Pb, Cd and Hg in samples of vegetable-growing soil were detected. The transverse, vertical spatio-temporal variation of heavy metals in soil was analyzed on the base of field investigations and laboratory analysis. The results show that: (1) in soil used for vegetable production, the levels of heavy metals decreased gradually from urban to rural areas; the levels of the main heavy metals in urban areas are significantly higher than suburban and rural areas; (2) the means of the levels of heavy metals, calculated by subtracting the sublayer (15–30 cm) from the toplayer (0–15 cm), are all above zero and large in absolute value in urban areas, but in suburban and rural areas, the means are all above or below zero and small in absolute value. The causes of spatial and temporal variation were analyzed as follows: one cause was associated with mellowness of the soil and the length of time the soil had been used for vegetable production; the other cause was associated with population density and industrial intensity decreasing along the urban to rural gradient (i.e., urbanization levels can explain the distribution of heavy metals in soil to some extent). Land uses should be planned on the basis of heavy metal pollution in soil, especially in urban and suburban regions. Heavily polluted soils have to be expected from food production. Further investigation should be done to determine whether and what kind of agricultural production could be established near urban centers
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