Plant Growth Hormones

Many factors can cause and affect cell growth in the plant such as external (environmental) and internal factors; one of the most important internal factors is plant growth hormones. Many hormones required for cell growth, such as auxins, gibberellins, brassinosteroids, ethylene, jasmonates, salicylic acid, strigolactones and cytokinins which able to accelerate or promote growth, but, some hormone-like abscisic acid has an adverse effect on growth which increases seed dormancy by inhibiting cell growth. Also, plant hormones are able to breakdowns dormancy for many plants and can alleviate abiotic stress (salinity, extreme temperatures and, drought,…) which led to enhance germination and improve growth for many plants, whether naturally occurring in the plant or by adding it to the plant in its artificially formed or in the form of bio- or nano-fertilization in order to increase the productivity and improve its efficiency under extreme conditions. Therefore, this chapter will highlight and will provide data for the positive or/and negative effect of these hormones on many plants to achieve a rapid germination method. It will also shed light on the relationship of these hormones to some enzymes to accelerate growth

Mucin1 expression and gustatory function in postmenopausal females : a case-control observational study

Investigating possible relationship between Mucin1 expression levels in saliva, gustatory function, and taste perception in postmenopausal females. Using whole mouth taste test, twenty-five post-menopausal females (51.35 ± 5.22 years) and twenty-five p

Role of Proangiogenic Tyrosine Kinase with Immunoglobulin and Endothelial Growth Factor Homology Domains 2 Expressing Monocytes in Chronic Lymphocytic Leukemia

Background: Globally, highest hematologic malignancy in prevalence is considered chronic lymphocytic leukemia (CLL). The expression of angiopoietin-2 (Ang2) and tyrosine kinase with immunoglobulin and endothelial growth factor homology domains (Tie1), two critical components of the Ang-Tie2 pro-angiogenic pathway, in CLL cells has been demonstrated. Objective: Clarification of Tie2-expressing monocytes’ (TEMs) involvement in the pathophysiology of CLL is the goal of this study. Patients and Methods: The study was case control, which was performed on 21 CLL patients; their age ranged from 46 to 71 with a mean of 58.2 ± 6.9, in addition to 21 age and sex matched healthy control subjects. Full medical histories, clinical examinations, and laboratory tests were conducted on all individuals. The percentage of TEMs in peripheral blood was determined by flow cytometry and their phenotypic characteristics defined as CD14+/CD16+/Tie-2+ cells. Results: Compared to the control group, there was a statistically significant increase in TEMs in the cases group. Among the cases group there was a statistical significant increase in LDH, uric acid, WBCs, reticulocyte, CD 38 β2 microglobulin and TEMS and statistical significant decrease in Hb with increase Binet stage. There was a statistical significant +ve correlation between TEMs and LDH, WBCs, reticulocytes, CD38 and β2 microglobulin. Also, there was a statistical significant negative correlation between TEMs and Hb and platelets count among the cases group. TEMs percentage had sensitivity, specificity and accuracy (100%) in diagnosis of leukemia at cut off > 20.95%. Conclusion: TEMs could be a part of CLL pathogenesis which can be a predictor of disease progression alongside with other prognostic indicators

Effect of An Educational Intervention About Occupational Safety on Knowledge and Practices of Male Students in Technical Mechanical Secondary Schools in El-Behira Governorate

Background. Occupational health and safety is one of the most important aspects of human concern. The Aim of this study is to evaluate the effect of educational intervention about occupational safety on knowledge and practice of male students in technical mechanical secondary schools in El-Behira governorate. Hypothesis: Technical Mechanical secondary school male students who engage in occupational safety intervention will demonstrate higher level of knowledge and practice than those who are not . Material and Methods: Quasi-experimental pre/post–test research design. Settings: the study was conducted in four technical mechanical secondary schools in El-Behira governorate. Subjects: the study was carried on 280 students (140 were cases and 140 were control).Data collection tools: data were collected using three tools: structured self-administered questionnaire, Students' knowledge regarding occupational safety and observation check list regarding safety measures practices in the training workshops.Results: conveyed that less than half (46.4%, 47.9%) of both the study and the control group respectively were aged between   16 to less than 17 years. All the study group and the control one had poor knowledge regarding occupational health and safety before conduction of the educational intervention, whereas after implementation of the educational intervention, more than three quarters of the study group (85.7%) had good knowledge whereas the vast majority of the control group (99.3%) still had poor knowledge  . There was a statistically significant relation between the department and the total knowledge score of the study group (X2= 14.150 , P=0.007*).Conclusion: The educational program is successful in attaining its aim of positively improving knowledge, and practice of the study group   about Occupational Health and Safety.Recommendations: this study recommend the necessity of provision of personal protective equipment to the students in the school workshops and integrating occupational safety topics in their curriculum. Keywords: Educational intervention, occupational health, Knowledge, Technical secondary schools. DOI: 10.7176/JHMN/80-05 Publication date:September 30th 202

Intervention Study to Upgrade Patient Safety Practices in Pediatric Intensive Care Units of Cairo University Children Hospital

BACKGROUND: The World Health Organization calls patient safety “an endemic concern.†Keeping patients safe is viewed as a global public health problem and a human rights issue. An environment where safety culture prevails is considered the biggest obstacle to improve patient safety. Proactive efforts to identify, prevent, and eliminate errors have the potential to significantly improve safety. Pediatric intensive care unit (PICU) is high-hazard and -risk environments. AIM: The aim of this study is to enhance compliance to patient safety practices within the general PICUs in Cairo University Children’s Hospital. METHODS: This is a pretest-posttest interventional study. A tailored intervention after the baseline assessment was designed and implemented followed by reassessment. All physicians and nurses present in the general PICUs who were available and consented participated in the study. A questionnaire for knowledge and attitude and a checklist for practice assessment of the participants were used. RESULTS: The median age of the participants was 30 years and interquartile range (28–40). There was a statistically significant difference between those who received patient safety training and those who did not in patient safety knowledge. The median knowledge score increased significantly after the intervention. Regarding the attitude of the studied personnel toward their perception of patient safety culture’s dimensions before and after the intervention, there was no statistically significant difference in some dimensions and a statistically significant improvement in some others. CONCLUSION: The strategies based on patient safety awareness-raising among health-care providers together with commitment and enthusiasm among senior leadership in the hospital can potentially improve compliance with practice and consequently lead to better patient safety

Sero-prevalence and risk factors associated with toxoplasma gondii infection among pregnant women in Alexandria, Egypt

Background: Toxoplasma gondii infection during pregnancy can result in fetal death, neonatal death or various congenital defects. This study aimed to estimate the seroprevalence of toxoplasma gondii infection using two different diagnostic tests, Enzyme-Linked Immunosorbent Assay (ELISA) versus Immunochromatographic assay (ICA) and to study the potential risk factors for acquiring infection in pregnant women attending antenatal care clinics in Alexandria, Egypt.Methods: A cross sectional study, conducted between May 2015 and June 2016. The study was done in antenatal care centers of most districts of Alexandria Governorate, Egypt. 382 pregnant women, of a gestational age between 8-40 weeks were included in the study and were given pretested structured questionnaire to assess risk factors, which included: demographic, socio-economic data, kitchen hygiene and behavioral variables. Blood samples were taken and sera were divided into two parts; the first part was examined for anti-T.gondii IgG and IgM antibodies using rapid diagnostic test RDT kit, the other part tested by ELISA.Results: The overall seroprevalence of T.gondii infection was (11.3%) detected by RDT, significantly increased to (57.9%) by ELISA test (X2= 5.3; p=0.001). RDT had the sensitivity of (15.8%), the specificity of (95%), PPV of (81.4%), NPV of (45.1%), with overall diagnostic efficiency of (49.2%). The association between T.gondii infection and the age of the pregnant women was found to be statistically significant (OR=2.84, 95%CI=1.251-6.455).Conclusions: The present study has documented a bad diagnostic performance of RDT in detection T.gondii in serum samples of infected pregnant women as compared to ELISA technique. Age is the only risk factor to be associated statistically with toxoplasma gondii infection

INFLUENCE OF PLANTING DATES AND SOME CHEMICAL SUBSTANCES ON ROOTING OF PHYTOLACCA DIOICA

The present study was carried out under plastic house conditions at the nursery of Zohria garden, Hort. Res. Inst., ARC, Cairo, Egypt throughout the two successive seasons of 2015 and 2016 to reveal the effect of planting dates (winter, spring, summer and autumn), some rooting promoters at different concentrations i.e. IBA, NAA, 2,4-D, catechol, cinnamic acid and tryptophan (alone or in combination) and their interactions on rooting of hard-to-root ornamental tree Phytolacca dioica.Results revealed thatplanting in spring increased rooting percentage (%) and root length (cm) in both seasons to the highest values. Treating the cuttings with IBA at 4000 ppm + NAA at 4000 ppm formulation resulted in the highest rooting percentage (%) in both seasons. Although there was no clear trend that could be observed from the obtained results, planting cuttings in either spring or autumn in addition to treating with IBA at 4000 ppm + NAA at 4000 ppm formulation increased rooting percentage (%) to the highest values.In conclusion, to achieve a successful vegetative propagation and to induce rooting on cuttings it is recommended to plant the cuttings in either spring or autumn in addition to treating with IBA at 4000 ppm + NAA at 4000 ppm formulation

Adenosine A2A Receptor Blockade Prevents Rotenone-Induced Motor Impairment in a Rat Model of Parkinsonism

Pharmacological studies implicate the blockade of adenosine receptorsas an effective strategy for reducing Parkinson’s disease (PD) symptoms. The objective of this study is to elucidate the possible protective effects of ZM241385 and 8-cyclopentyl-1, 3-dipropylxanthine, two selective A2A and A1 receptor antagonists, on a rotenone rat model of PD. Rats were split into four groups: vehicle control (1 ml/kg/48 h), rotenone (1.5 mg/kg/48 h, s.c.), ZM241385 (3.3 mg/kg/day, i.p) and 8-cyclopentyl-1, 3-dipropylxanthine (5 mg/kg/day, i.p). After that, animals were subjected to behavioral (stride length and grid walking) and biochemical (measuring concentration of dopamine levels using high performance liquid chromatography, HPLC). In the rotenone group, rats displayed a reduced motor activity and disturbed movement coordination in the behavioral tests and a decreased dopamine concentration as foundby HPLC. The effect of rotenone was partially prevented in the ZM241385 group, but not with 8-cyclopentyl-1,3-dipropylxanthine administration. The administration of ZM241385 improved motor function and movement coordination (partial increase of stride length and partial decrease in the number of foot slips) and an increase in dopamine concentration in the rotenone-injected rats. However, the 8-cyclopentyl-1,3-dipropylxanthine and rotenone groups were not significantly different. These results indicate that selective A2A receptor blockade by ZM241385, but not A1 receptor blockadeby 8-cyclopentyl-1,3-dipropylxanthine, may treat PD motor symptoms. This reinforces the potential use of A2A receptor antagonists as a treatment strategy for PD patients

Spice Foods effects on Body Weight Reductions between Obese Animal Models

The aim of this study was determination and identification of phenolic and flavonoids fraction in addition to the antioxidant activities of used herbals (curcumin, black pepper and cumin) by HPLC in addition to evaluating the effects of such different spicy food consumptions on body weight reduction between obese animal models. Rats were randomly divided to ten groups fed; Black Papers, Cumin and Curcumin either alone or in different mixtures additionally to groups fed Orlistat (control body weight loss), Non-obese negative control group (C-ve) and Obese control positive group (C+ve). Blood glucose and body weight levels were measured at the beginning and end of the experimental in addition to rats’ lipid profiles (total cholesterol; triglycerides;, high dense lipoprotein cholesterol; low dense lipoprotein cholesterol; and very low dense lipoprotein cholesterol). Results presented that obese models received (Cumin)  Cu/( Curcumin ) Cur mixture have the biggest effective significant treatment (about -80% body weight reduction  ) followed by both groups fed mixtures of (Curcumin ) Cur/( Black Papers ) Bp  and (Curcumin) Cur/( Black Papers ) Bp/( Cumin ) Cu; decreased by -68.0 and -65.6g respectively. The study could be more valuable causing significant body weight reduction between obese models, however human studies are needed

RESPONSE OF ARTOCARPUS HETEROPHYLLUS LAM. TO SOME NATURAL EXTRACTS AT THE EARLY GROWTH STAGES 2- CHEMICAL CONSTITUENTS OF THE PLANTS

The experimental trial was consummated under saran house of 65% shading performed at the nursery of Horticulture Research Institute, Giza, Egypt during two successive seasons (2012/2013 and 2013/2014) with the aim of improving plant quality at the early growth stages of Artocarpus heterophyllus Lam. by studying the effect of treating plants with some natural botanical extracts (Moringa oleifera Lam., Thymus vulgaris L. and Majorana hortensis Moench) with different levels (0, 5 and 10%) besides, the combinations of moringa + marjoram, moringa + thyme and marjoram + thyme extracts at 2.5%. All of them were applied as a foliar spray commencing from November 20th in both seasons on transplants of Artocarpus hetrophyllus Lam. 14-15 cm height with 4-5 leaves till June 20th of the following year at 15 days interval. The plants were grown in sand + peatmoss mixture (1:1, v/v). The results emphasized that most plants which received the highest natural extract level (10%) died after about 6 times of spraying. So, the corresponding data of such treatments were excluded. Meanwhile, using either moringa extract at 5% or the combination of marjoram + thyme extracts at 2.5% proved their mastery in improving plant chemical constituents at the terminate of experiment (July,5th) as that treating plants with moringa extract at 5% followed by that of the combination of marjoram + thyme extracts at 2.5% were the best treatments used for improving all the components which were measured in this respect (chlorophyll a, b and carotenoids, total carbohydrates, N, P, K and protein in leaves). From the aforementioned results, it could be recommended to use either moringa extract at 5% or the combination of marjoram + thyme extras at 2.5% for improving chemical constituents of Artocarpus heterophyllus Lam. at the early growth stages of such plants besides, getting better plants without being forced to use chemical nutrients or synthetic growth regulators that may contaminate the environment with getting a safe clean product